A. Shih, R. Misra, and M. G. Rush, Detection of multiple, novel reverse transcriptase coding sequences in human nucleic acids: Relation to primate retrovirus, J Virol, vol.63, pp.64-75, 1989.

M. Lindeskog, P. Medstrand, and J. Blomberg, Sequence variation of human endogenous retrovirus ERV9-related elements in an env region corresponding to an immunosuppressive peptide: Transcription in normal and neoplastic cells, J Virol, vol.67, pp.1122-1126, 1993.

D. H. Mack and J. J. Sninsky, A sensitive method for the identification of uncharacterized viruses related to known virus groups: Hepadnavirus model system, Proc Nati Acad Sei, vol.85, pp.6997-6981, 1988.

L. A. Donehower, R. C. Bohannon, R. J. Ford, and R. A. Gibbs, The use of primers from highly conserved pol regions to identify uncharacterized retroviruses by polymerase chain reaction, J Virol Methods, vol.28, pp.33-39, 1990.

P. Medstrand and J. Blomberg, Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: Differential transcription in normal human tissues, J Virol, vol.67, pp.6778-6787, 1993.

S. J. Greenberg, G. D. Ehrlich, M. A. Abbott, B. J. Hurwitz, T. A. Waldmann et al., Detection of sequences homologous to human retroviral DNA in multiple sclerosis by gene amplification, Proc Nati Acad Sei, vol.86, pp.2878-2882, 1989.

H. Koprowski, E. C. Defreitas, M. E. Harper, M. Sandberg-wollheim, W. A. Sheremata et al.,

F. Wong-staal and R. C. Gallo, Multiple sclerosis and human T-cell lymphotropic retroviruses, Nature (London), vol.318, pp.154-160, 1985.

H. Perron, C. Geny, A. Laurent, C. Mouriquand, J. Pellat et al., Leptomeningeal cell line from multiple sclerosis with reverse transcriptase activity and viral particles, Res Virol, vol.140, pp.551-561, 1989.

H. B. Rasmussen, H. Perron, and J. Clausen, Do endogenous retroviruses have etiological implications in inflammatory and degenerative nervous system diseases?, Acta Neurol Scand, vol.88, pp.190-198, 1993.

E. P. Reddy, M. Sandberg-wollheim, R. V. Mettus, P. E. Ray, D. Freitas et al., Amplification and molecular cloning of HTLV-I sequences from DNA of multiple sclerosis patients, Science, vol.243, pp.529-533, 1989.

F. Rozenberg, S. Lefebvre, C. Lubetzki, P. Lebon, O. Lyon-caen et al., Analysis of retroviral sequences in the spinal form of multiple sclerosis, Ann Neurol, vol.29, pp.333-336, 1991.

C. Bangham, S. Nightingale, J. K. Cruickshank, and S. Daenke, PCR analysis of DNA from multiple sclerosis patients for the presence of HTLV-I, Science, vol.246, p.821, 1989.

J. H. Richardson, K. W. Wucherpfennig, N. Endo, P. Rudge, A. G. Dalgleish et al., PCR analysis of DNA from multiple sclerosis patients for the presence of HTLV-I, Science, vol.246, pp.821-823, 1989.

G. B. Ehrlich, J. B. Glaser, V. Bryz-gornia, J. Maese, T. A. Waldmann et al., Multiple sclerosis, retroviruses, and PCR, vol.41, pp.335-343, 1991.

D. French, S. Mammarella, M. C. Curia, A. M. Porrini, A. Giampietro et al., Amplifications of multiple regions of the HTLV-I genome from DNA of an Italian spastic paraparesis patient but not from DNA of multiple sclerosis patients, J Neurol Sei, vol.103, pp.82-89, 1991.

N. Prayoonwiwat, L. R. Pease, and M. Rodriguez, Human T-cell lymphotropic virus type I sequences detected by nested polymerase chain reactions are not associated with multiple sclerosis, Mayo Clin Proc, vol.66, pp.665-679, 1991.

J. M. Chirgwin, A. E. Przybyla, R. J. Macdonald, and R. Wj, Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry, vol.18, pp.5294-5299, 1979.

R. Maniatis, E. F. Fritsch, and J. Sambrook, Molecular Cloning: A Laboratory Manual Cold Spring Harbor Laboratory, 1982.

D. G. Higgins, A. J. Bleasby, S. Fuchs, and . Clustal-v, Improved software for multiple sequence alignment, Comp Applic Biosci, vol.8, pp.189-191, 1992.

N. Saitou and M. Nei, The neighbor-joining method: A new method for reconstructing phylogenetic trees, Mol Biol Evol, vol.4, pp.406-425, 1987.

L. Mantia, G. Maglione, D. Pengue, G. , D. Cristofano et al., Identification and characterization of novel human endogenous retroviral sequences preferentially expressed in undifferentiated embryonal carcinoma cells, Nucleic Acids Res, vol.19, pp.1513-1520, 1991.

M. Ono, T. Yasunaga, T. Miyata, and H. Ushikubo, Nucleotide sequence of human endogenous retrovirus genome related to the mouse mammary tumor virus genome, J Virol, vol.60, pp.589-598, 1986.

S. Kato, K. Matsuo, N. Nishimura, N. Takahashi, and T. Takano, The entire nucleotide sequence of baboon endogenous virus DNA: A chimeric genome structure of murine type C and simian type D retroviruses, Jpn J Genet, vol.62, pp.127-137, 1987.

C. P. Van-beveren, F. Van-straaten, J. A. Galleshaw, and I. M. Verma, Nucleotide sequence of the genome of a murine sarcoma virus, Cell, vol.27, pp.97-108, 1981.

N. Sagata, T. Yasunaga, J. Tsuzuku-kawamura, K. Ohishi, Y. Ogawa et al., Complete nucleotide sequence of the genome of bovine leukemia virus: Its evolutionary relationship to other retroviruses, Proc Nati Acad Sei, vol.82, pp.677-681, 1985.

K. C. Deen and R. W. Sweet, Murine mammary tumor virus pol-related sequences in human DNA; characterization and sequence comparison with the complete murine mammary tumor virus pol gene, J Virol, vol.57, pp.422-432, 1986.

R. Moore, M. Dixon, R. Smith, G. Peters, and C. Dickson, Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: Two frameshift suppression events are required for translation of gag and pol, J Virol, vol.61, pp.480-490, 1987.

D. F. York, R. Vigne, D. W. Verwoerd, and G. Querat, Nucleotide sequence of the jagsiekte retrovirus, an exogenous and endogenous type D and B retrovirus of sheep and goats, J Virol, vol.66, pp.4930-4939, 1992.

R. M. Thayer, M. D. Power, M. L. Bryant, M. B. Gardner, P. J. Barr et al., Sequence relationships of type D retrovirus which cause simian acquired immunodeficiency syndrome, Virology, vol.157, pp.317-329, 1987.

A. J. Dorner, F. Bonneville, R. W. Kriz, K. Kelleher, K. Bean et al., Molecular cloning and characterization of a complete Chinese hamster provirus related to intracisternal A particle genomes, J Virol, vol.65, pp.4713-4719, 1991.

M. Ono, B. H. Toh, T. Miyata, and T. Awaya, Nucleotide sequence of the Syrian hamster intracisternal A-particle gene: Close evolutionary relationship of type A particle gene to types B and D oncovirus genes, J Virol, vol.55, pp.387-394, 1985.

S. Ymer, W. Tucker, H. D. Campbell, and Y. Ig, Nucleotide sequence of the intracisternal A-particle genome inserted 5' to the interleukin-3 gene of the leukemia cell line WEHI-3B, Nucleic Acids Res, vol.14, pp.5901-5918, 1986.

P. Sonigo, M. Alizon, K. A. Staskus, D. Klatzmann, S. Cole et al., Nucleotide sequence of the visna lentivirus: Relationship to the AIDS virus, Cell, vol.42, pp.369-382, 1985.

M. Guyader, M. Emerman, P. Sonigo, F. Clavel, L. Montagnier et al., Genome organization and transactivation of the human immunodeficiency virus type 2, Nature (London), vol.326, pp.662-669, 1987.

R. Buslei, P. L. Strissel, C. Henke, R. Schey, N. Lang et al., Activation and regulation of endogenous retroviral genes in the human pituitary gland and related endocrine tumours, Neuropathology and Applied Neurobiology, vol.41, issue.2, pp.180-200, 2015.

J. Lee, K. Ahn, Y. Kim, Y. Jung, and H. Kim, Radiation-Induced Human Endogenous Retrovirus (HERV)-R env Gene Expression by Epigenetic Control, Radiation Research, vol.178, issue.5, pp.379-384, 2012.

J. Lee and H. Kim, Radiation-induced retroelement-mediated genomic instability, Biotechnology and Bioprocess Engineering, vol.17, pp.439-445, 2012.

M. Mayne and . Johnston, Latent and Activated Brain Flora 363-395

D. Seilhean and J. Hauw, Neuropathologie der multiplen Sklerose 167-184

H. Kim, R. V. Wadekar, O. Takenaka, C. Winstanley, F. Mitsunaga et al., SINE-R.C2 (a Homo sapiens specific retroposon) is homologous to CDNA from postmortem brain in schizophrenia and to two loci in the Xq21.3/Yp block linked to handedness and psychosis, American Journal of Medical Genetics, vol.88, issue.5, pp.560-566, 1999.

H. Kim, R. V. Wadekar, O. Takenaka, C. Winstanley, F. Mitsunaga et al., SINE-R.C2 (a Homo sapiens specific retroposon) is homologous to CDNA from postmortem brain in schizophrenia and to two loci in the Xq21.3/Yp block linked to handedness and psychosis, American Journal of Medical Genetics, vol.88, issue.5, pp.560-566, 1999.

C. Hohenadl, H. Germaier, M. Walchner, M. Hagenhofer, M. Herrmann et al., Christine Leib-Mösch. 1999. Transcriptional Activation of Endogenous Retroviral Sequences in Human Epidermal Keratinocytes by UVB Irradiation, Journal of Investigative Dermatology, vol.113, pp.587-594

. Monteyne, Multiple sclerosis: a secretive disease, Biomedicine & Pharmacotherapy, vol.53, issue.8, pp.341-343, 1999.

J. E. Robert-s-fujinami and . Libbey, Endogenous retroviruses: are they the cause of multiple sclerosis?, Trends in Microbiology, vol.7, issue.7, pp.263-264, 1999.

P. Olsson, B. Ryberg, R. Awad, S. Ammoun, H. Yin et al., Retroviral RNA Related to ERV9/MSRV in a Human Serum: A New Sequence Variant, AIDS Research and Human Retroviruses, vol.15, issue.6, pp.591-593, 1999.

J. H-perron and . Seigneurin, Human retroviral sequences associated with extracellular particles in autoimmune diseases: epiphenomenon or possible role in aetiopathogenesis, Microbes and Infection, vol.1, issue.4, pp.309-322, 1999.

P. Monteyne, J. Bureau, and M. Brahic, Viruses and multiple sclerosis, Current Opinion in Neurology, vol.11, pp.287-291, 1998.

M. Brahic and J. Bureau, Multiple sclerosis and retroviruses, Annals of Neurology, vol.42, pp.984-985, 1997.

. Froussard, Is LM7 a new human retrovirus or a mycoplasma virion, Multiple Sclerosis Journal, vol.1, issue.2, pp.88-94, 1995.

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