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Journal articles
Homology between a 173-kb Region from Mouse Chromosome 10, Telomeric to the Ifng Locus, and Human Chromosome 12q15
Abstract : We sequenced a 173-kb region of mouse chromosome 10, telomeric to the Ifng locus, and compared it with the human homologous sequence located on chromosome 12q15 using various sequence analysis programs. This region has a low density of genes: one gene was detected in the mouse and the human sequences and a second gene was detected only in the human sequence. The mouse gene and its human orthologue, which are expressed in the immune system at a low level, produce a noncoding mRNA. Nonexpressed sequences show a higher degree of conservation than exons in this genomic region. At least three of these conserved sequences are also conserved in a third mammalian species (sheep or cow).
Cited literature [42 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-02097174
Contributor : Jean-François Bureau Connect in order to contact the contributor
Submitted on : Thursday, April 11, 2019 - 7:14:15 PM
Last modification on : Monday, December 13, 2021 - 9:16:09 AM
Contributor : Jean-François Bureau Connect in order to contact the contributor
Submitted on : Thursday, April 11, 2019 - 7:14:15 PM
Last modification on : Monday, December 13, 2021 - 9:16:09 AM
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