Invasive serogroup w meningococcal disease in children: a national survey from 2001 to 2008 in France.

Jean Gaschignard (1, 2, 3) , Corinne Levy (3, 4) , Ala-Eddine Deghmane (5) , Francois Dubos (3, 6) , Mathias Muszlak (7) , Robert Cohen (3, 4) , Edouard Bingen (3, 1, 2) , Albert Faye (3, 1, 2) , Muhamed-Kheir Taha (5)

1 AP-HP Hôpital universitaire Robert-Debré [Paris]
2 UPD7 - Université Paris Diderot - Paris 7
3 GPIP - Groupe de Pathologie Infectieuse Pédiatrique [Paris]
4 ACTIV - Association Clinique et Thérapeutique Infantile du Val de Marne
5 CNR - Centre National de Référence des Méningocoques et Haemophilus influenzae - National Reference Center Meningococci and Haemophilus influenzae
6 CHRU Lille - Centre Hospitalier Régional Universitaire [Lille]
7 Centre Hospitalier de Mayotte

From 2001 to 2008, 119 pediatric cases of meningococcal disease caused by serogroup W were reported in France. They cases represented 4% of all meningococcal disease cases in children and were mostly in infants (54%). Meningitis occurred in 78 (66%) patients but differed by isolate. Isolates of the clonal complex sequence type-22 were associated with nonmeningeal presentation. Further investigations of clinical tropism of meningococcal W isolates are warranted.

Domains: Life Sciences [q-bio]; Santé publique et épidémiologie

Jean Gaschignard, Corinne Levy, Ala-Eddine Deghmane, Francois Dubos, Mathias Muszlak, et al.. Invasive serogroup w meningococcal disease in children: a national survey from 2001 to 2008 in France.. Pediatric Infectious Disease Journal, 2013, 32 (7), pp.798-800. ⟨10.1097/INF.0b013e31828e9e91⟩. ⟨pasteur-02095661⟩