Skip to Main content Skip to Navigation
Journal articles

Laboratory evaluation of a rapid diagnostic test for Neisseria meningitidis serogroup A.

Aude Terrade 1 Jean-Marc Collard 2 Farida Nato 3 Muhamed-Kheir Taha 1, *
* Corresponding author
1 CC-OMS - WHO-CC - Centre Collaborateur de l'OMS pour les méningites bactériennes - WHO Collaborating Center Bacterial Meningitis
2 CERMES - Centre de Recherche Médicale et Sanitaire (Niamey, Niger)
3 Production de Protéines Recombinantes et d'Anticorps (Plate-Forme)
Abstract : BACKGROUND: Epidemics of meningococcal meningitis occur periodically in the African 'meningitis belt' and are mainly, but not only, due to serogroup A. METHODS: We tested a dipstick as a rapid detection test (RDT) to detect serogroup A using 401 cerebrospinal fluid (CSF) samples. RESULTS: The detection limits were 10(5) CFU/ml with sensitivity and specificity for detecting serogroup A in CSF samples of 88% and 99%, respectively. CONCLUSIONS: The new RDT can be used in field surveillance of meningococcal meningitis to help characterize meningitis cases particularly after introduction of the conjugate vaccine against serogroup A.
Keywords : Diagnosis Meningitis Neisseria meningitidis Rapid test Serogroup A
Document type :
Journal articles
Complete list of metadata
https://hal-pasteur.archives-ouvertes.fr/pasteur-02088923
Contributor : Marie Martin Connect in order to contact the contributor
Submitted on : Wednesday, April 3, 2019 - 12:09:45 PM
Last modification on : Friday, November 5, 2021 - 5:32:01 PM

Identifiers

Collections

PASTEUR | RIIP_CERMES | RIIP

Citation

Aude Terrade, Jean-Marc Collard, Farida Nato, Muhamed-Kheir Taha. Laboratory evaluation of a rapid diagnostic test for Neisseria meningitidis serogroup A.. Transactions of The Royal Society of Tropical Medicine and Hygiene, Oxford University Press (OUP), 2013, 107 (7), pp.460-461. ⟨10.1093/trstmh/trt041⟩. ⟨pasteur-02088923⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Les métriques sont temporairement indisponibles