Lineage specification in the mouse preimplantation embryo, DEVELOPMENT, vol.143, issue.7, pp.1063-1074, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01923150
Anatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo, GENESIS, vol.51, issue.4, pp.219-233, 2013. ,
The Genetic Regulation of Cell Fate During Preimplantation Mouse Development, CURR. TOP. DEV. BIOL, vol.120, pp.173-202, 2016. ,
A close look at the mammalian blastocyst: epiblast and primitive endoderm formation, CELL. MOL. LIFE SCI, vol.71, issue.17, pp.3327-3338, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01923166
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst, DEVELOPMENT, vol.135, issue.18, pp.3081-3091, 2008. ,
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway, DEV. CELL, vol.10, issue.5, pp.615-624, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-01923174
Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst, DEVELOPMENTAL BIOLOGY, vol.313, issue.2, pp.594-602, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00352675
Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst, DEVELOPMENTAL BIOLOGY, vol.331, issue.2, pp.210-221, 2009. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01572044
Cell death in the mammalian blastocyst, MOLECULAR HUMAN REPRODUCTION, vol.3, issue.10, pp.919-925, 1997. ,
Mechanism of programmed cell death in the blastocyst, PROC. NATL. ACAD. SCI. U.S.A, vol.86, issue.10, pp.3654-3658, 1989. ,
FGF4 is required for lineage restriction and saltand-pepper distribution of primitive endoderm factors but not their initial expression in the mouse, DEVELOPMENT, vol.140, issue.2, pp.267-279, 2013. ,
FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst, DEVELOPMENTAL BIOLOGY, vol.384, issue.1, pp.65-71, 2013. ,
Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2, DEV. CELL, vol.41, issue.5, pp.496-510, 2017. ,
Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency, DEV. CELL, vol.41, issue.5, pp.511-526, 2017. ,
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo, DEVELOPMENT, vol.136, pp.3215-3222, 2009. ,
FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst, DEVELOPMENT, vol.137, issue.5, pp.715-724, 2010. ,
Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst, NATURE COMMUNICATIONS, vol.7, p.13463, 2016. ,
ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation, SCI. REP, vol.7, issue.1, p.12285, 2017. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02075462
A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst, DEVELOPMENT, vol.137, issue.20, pp.3361-3372, 2010. ,
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst, STEM CELLS, vol.31, issue.9, pp.1932-1941, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02075472
Oncogenes and signal transduction, CELL, vol.64, issue.2, pp.281-302, 1991. ,
Role of platelet-derived growth factors in physiology and medicine, GENES & DEVELOPMENT, vol.22, issue.10, pp.1276-1312, 2008. ,
Spatial and temporal patterns of c-kitexpressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos, DEVELOPMENT, vol.122, issue.10, pp.3023-3033, 1996. ,
The potential role of stem cell factor and its receptor c-kit in the mouse blastocyst implantation, MOLECULAR HUMAN REPRODUCTION, vol.5, issue.9, pp.874-879, 1999. ,
Tumor spectrum analysis in p53-mutant mice, CURRENT BIOLOGY, vol.4, issue.1, pp.1-7, 1994. ,
Evolutionary divergence of plateletderived growth factor alpha receptor signaling mechanisms, MOL. CELL. BIOL, vol.23, issue.11, pp.4013-4025, 2003. ,
Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes, GENESIS, vol.26, issue.2, pp.110-112, 2000. ,
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth, DEVELOPMENT, vol.130, issue.13, pp.3063-3074, 2003. ,
LIF supports primitive endoderm expansion during preimplantation development, DEVELOPMENT, vol.142, issue.20, pp.3488-3499, 2015. ,
Impaired Mitotic Progression and Preimplantation Lethality in Mice Lacking OMCG1, a New Evolutionarily Conserved Nuclear Protein, MOL. CELL. BIOL, vol.25, issue.14, pp.6289-6302, 2005. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02075522
A novel model to study the dorsolateral migration of melanoblasts, MECH. DEV, vol.89, issue.1-2, pp.3-14, 1999. ,
The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway, JOURNAL OF CELL SCIENCE, vol.119, pp.3039-3046, 2006. ,
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors, J. PHARMACOL. EXP. THER, vol.295, issue.1, pp.139-145, 2000. ,
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells, NATURE MEDICINE, vol.2, issue.5, pp.561-566, 1996. ,
Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst, DEV. CELL, vol.18, issue.4, pp.675-685, 2010. ,
Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages, NATURE CELL BIOLOGY, vol.16, issue.1, pp.27-37, 2014. ,
PI3K-mediated PDGFR? signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways, GENES & DEVELOPMENT, vol.28, issue.9, pp.1005-1017, 2014. ,
Conditional inactivation of PDCD2 induces p53 activation and cell cycle arrest, BIOL OPEN, vol.3, issue.9, pp.821-831, 2014. ,
p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression, NATURE CELL BIOLOGY, vol.7, issue.2, pp.165-171, 2005. ,
Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination, DEVELOPMENT, vol.143, issue.17, pp.3050-3060, 2016. ,
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast, SCIENCE, vol.253, issue.5022, pp.905-909, 1991. ,
Abstract B148: INK128 is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity, MOL CANCER THER, vol.8, pp.148-148, 2009. ,
Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins, MOL. CELL. BIOL, vol.16, issue.4, pp.1759-1769, 1996. ,
Cell-surface proteomics identifies lineagespecific markers of embryo-derived stem cells, DEV. CELL, vol.22, issue.4, pp.887-901, 2012. ,
Distinct mechanisms for PDGF and FGF signaling in primitive endoderm development, DEVELOPMENTAL BIOLOGY, vol.442, issue.1, pp.155-161, 2018. ,
Transformation-related protein 53 expression in the early mouse embryo compromises preimplantation embryonic development by preventing the formation of a proliferating inner cell mass, BIOLOGY OF REPRODUCTION, vol.83, issue.6, pp.958-964, 2010. ,
Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells, MOLECULAR CELL, vol.46, issue.1, pp.30-42, 2012. ,
Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase, MAMM GENOME, vol.13, issue.3, pp.169-172, 2002. ,
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells, MOL. CELL. BIOL, vol.24, issue.15, pp.6710-6718, 2004. ,
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development, MOL. CELL. BIOL, vol.24, issue.21, pp.9508-9516, 2004. ,
URL : https://hal.archives-ouvertes.fr/hal-02126925
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1, DEV. CELL, vol.11, issue.6, pp.859-871, 2006. ,
Inhibition of mTOR induces a paused pluripotent state, NATURE, vol.540, issue.7631, pp.119-123, 2016. ,