S. Jablonska, S. Majewski, S. Obalek, and G. Orth, Cutaneous warts, Clin Dermatol, vol.15, pp.309-319, 1997.

G. Orth, Genetics of epidermodysplasia verruciformis: Insights into host defense against papillomaviruses, Semin Immunol, vol.18, pp.362-374, 2006.

S. Majewski and S. Jablonska, Epidermodysplasia verruciformis as a model of human papillomavirus-induced genetic cancers: the role of local immunosurveillance, Am J Med Sci, vol.304, pp.174-179, 1992.

S. Majewski, S. Jablonska, and G. Orth, Epidermodysplasia verruciformis. Immunological and nonimmunological surveillance mechanisms: role in tumor progression, Clin Dermatol, vol.15, pp.321-334, 1997.

N. Ramoz, L. A. Rueda, B. Bouadjar, L. S. Montoya, and G. Orth, Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis, Nat Genet, vol.32, pp.579-581, 2002.
URL : https://hal.archives-ouvertes.fr/pasteur-00174726

A. I. Su, T. Wiltshire, S. Batalov, H. Lapp, and K. A. Ching, A gene atlas of the mouse and human protein-encoding transcriptomes, Proc Natl Acad Sci U S A, vol.101, pp.6062-6067, 2004.

M. Lazarczyk, C. Pons, J. A. Mendoza, P. Cassonnet, and Y. Jacob, Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses, J Exp Med, vol.205, pp.35-42, 2008.

M. Karin, Nuclear factor-kappaB in cancer development and progression, Nature, vol.441, pp.431-436, 2006.

N. D. Perkins and T. D. Gilmore, Good cop, bad cop: the different faces of NFkappaB, Cell Death Differ, vol.13, pp.759-772, 2006.

M. Van-hogerlinden, G. Auer, and R. Toftgard, Inhibition of Rel/Nuclear Factor-kappaB signaling in skin results in defective DNA damage-induced cell cycle arrest and Ha-ras-and p53-independent tumor development, Oncogene, vol.21, pp.4969-4977, 2002.

M. Dajee, M. Lazarov, J. Y. Zhang, T. Cai, and C. L. Green, NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia, Nature, vol.421, pp.639-643, 2003.

F. Colotta, P. Allavena, A. Sica, C. Garlanda, and A. Mantovani, Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability, Carcinogenesis, vol.30, pp.1073-1081, 2009.

G. Gaud, D. Guillemot, Y. Jacob, M. Favre, and F. Vuillier, EVER2 protein binds TRADD to promote TNF-alpha-induced apoptosis, Cell Death Dis, vol.4, p.499, 2013.

M. S. Hayden and S. Ghosh, Signaling to NF-kappaB, Genes Dev, vol.18, pp.2195-2224, 2004.

B. Liu, E. Park, F. Zhu, T. Bustos, and J. Liu, A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas, Proc Natl Acad Sci U S A, vol.103, pp.17202-17207, 2006.

E. Park, F. Zhu, B. Liu, X. Xia, and J. Shen, Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas, Cancer Res, vol.67, pp.9158-9168, 2007.

A. Page, M. Navarro, M. Garin, P. Perez, and M. L. Casanova, IKKbeta leads to an inflammatory skin disease resembling interface dermatitis, J Invest Dermatol, vol.130, pp.1598-1610, 2010.

B. Liu, J. Willette-brown, S. Liu, X. Chen, and S. M. Fischer, IKKalpha represses a network of inflammation and proliferation pathways and elevates cMyc antagonists and differentiation in a dose-dependent manner in the skin, Cell Death Differ, vol.18, pp.1854-1864, 2011.

U. Senftleben, Y. Cao, G. Xiao, F. R. Greten, and G. Krahn, Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway, Science, vol.293, pp.1495-1499, 2001.

M. M. Chaturvedi, B. Sung, V. R. Yadav, R. Kannappan, and B. B. Aggarwal, NFkappaB addiction and its role in cancer: 'one size does not fit all, Oncogene, vol.30, pp.1615-1630, 2011.

H. Y. Song, C. H. Regnier, C. J. Kirschning, D. V. Goeddel, and M. Rothe, Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factorkappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptorassociated factor 2, Proc Natl Acad Sci U S A, vol.94, pp.9792-9796, 1997.

M. Karin and E. Gallagher, TNFR signaling: ubiquitin-conjugated TRAFfic signals control stop-and-go for MAPK signaling complexes, Immunol Rev, vol.228, pp.225-240, 2009.

J. Y. Chung, Y. C. Park, H. Ye, and H. Wu, All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction, J Cell Sci, vol.115, pp.679-688, 2002.

S. Li, L. Wang, and M. E. Dorf, PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination, Mol Cell, vol.33, pp.30-42, 2009.

M. S. Hayden and S. Ghosh, Shared principles in NF-kappaB signaling, Cell, vol.132, pp.344-362, 2008.

V. Baud, Z. G. Liu, B. Bennett, N. Suzuki, and Y. Xia, Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain, Genes Dev, vol.13, pp.1297-1308, 1999.

H. Habelhah, S. Takahashi, S. G. Cho, T. Kadoya, and T. Watanabe, Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB, EMBO J, vol.23, pp.322-332, 2004.

J. R. Arron, Y. Pewzner-jung, M. C. Walsh, T. Kobayashi, and Y. Choi, Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling, J Exp Med, vol.196, pp.923-934, 2002.

I. Carpentier and R. Beyaert, TRAF1 is a TNF inducible regulator of NFkappaB activation, FEBS Lett, vol.460, pp.246-250, 1999.

C. Wang, A. J. Mcpherson, R. B. Jones, K. S. Kawamura, and G. H. Lin, Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection, J Exp Med, 2011.

E. Leo, Q. L. Deveraux, C. Buchholtz, K. Welsh, and S. Matsuzawa, TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis, J Biol Chem, vol.276, pp.8087-8093, 2001.

A. Wicovsky, F. Henkler, S. Salzmann, P. Scheurich, and C. Kneitz, Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation, Oncogene, vol.28, pp.1769-1781, 2009.

W. Xiong, J. E. Ferrell, and J. , A positive-feedback-based bistable 'memory module' that governs a cell fate decision, Nature, vol.426, pp.460-465, 2003.

J. J. Li, J. S. Rhim, R. Schlegel, K. H. Vousden, and N. H. Colburn, Expression of dominant negative Jun inhibits elevated AP-1 and NF-kappaB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes, Oncogene, vol.16, pp.2711-2721, 1998.

A. Limat and F. K. Noser, Serial cultivation of single keratinocytes from the outer root sheath of human scalp hair follicles, J Invest Dermatol, vol.87, pp.485-488, 1986.

J. G. Rheinwald and H. Green, Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells, Cell, vol.6, pp.331-343, 1975.

P. Y. Lozach, A. A. Bartosch, B. Virelizier, J. L. Arenzana-seisdedos, and F. , C-type lectins L-SIGN and DC-SIGN capture and transmit infectious hepatitis C virus pseudotype particles, J Biol Chem, vol.279, pp.32035-32045, 2004.

P. Cassonnet, C. Rolloy, G. Neveu, P. O. Vidalain, and T. Chantier, Benchmarking a luciferase complementation assay for detecting protein complexes, Nat Methods, vol.8, pp.990-992, 2011.
URL : https://hal.archives-ouvertes.fr/pasteur-01971619

I. E. Wertz and V. M. Dixit, Regulation of death receptor signaling by the ubiquitin system, Cell Death Differ, vol.17, pp.14-24, 2010.

S. C. Sun, Non-canonical NF-kappaB signaling pathway, Cell Res, vol.21, pp.71-85, 2011.