Skip to Main content Skip to Navigation
Journal articles

Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties

Abstract : An original gram-scale synthesis of O-acetylated forms of coelenterazine, furimazine or hydroxy-bearing analogues of luciferins is described. The comparison over two hours of their bioluminescence, using the nanoKAZ/NanoLuc luciferase, provides remarkable insights useful for the selection of a substrate adapted for a given application.
Document type :
Journal articles
Complete list of metadatas

Cited literature [57 references]  Display  Hide  Download

https://hal-pasteur.archives-ouvertes.fr/pasteur-02072739
Contributor : Yves Janin <>
Submitted on : Wednesday, October 23, 2019 - 11:21:53 AM
Last modification on : Saturday, April 11, 2020 - 2:15:08 AM
Long-term archiving on: : Friday, January 24, 2020 - 3:39:24 PM

File

OBC pour Hall 2019 (1).pdf
Files produced by the author(s)

Identifiers

Citation

Eloi Coutant, Sophie Goyard, Vincent Hervin, Glwadys Gagnot, Racha Baatallah, et al.. Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2019, 15, ⟨10.1039/c9ob00459a⟩. ⟨pasteur-02072739⟩

Share

Metrics

Record views

324

Files downloads

774