Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties
Abstract
An original gram-scale synthesis of O-acetylated forms of coelenterazine, furimazine or hydroxy-bearing analogues of luciferins is described. The comparison over two hours of their bioluminescence, using the nanoKAZ/NanoLuc luciferase, provides remarkable insights useful for the selection of a substrate adapted for a given application.
Origin : Files produced by the author(s)
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