Labex Who am I, Canc erop^ ole Ile de France (ORFOCRISE PME-2015) and Fondation pour la Recherche M edicale (ING20160435205) ,
, acknowledges funding by Institut Pasteur, Institut National du Cancer (INCa 2015-135), Fondation pour la Recherche M edicale (Equipe FRM DEQ20150331762), and the Inception program (ANR Investissement d'Avenir
,
Genome stability: DNA repair and recombination. London: Garland Science, 2014. ,
Homology search and choice of homologous partner during mitotic recombination, Mol Cell Biol, vol.19, pp.4134-4176, 1999. ,
Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences, Mol Cell Biol, vol.8, pp.3918-3946, 1988. ,
Effect of nuclear architecture on the efficiency of double-strand break repair, Nat Cell Biol, vol.15, pp.694-699, 2013. ,
Finding a match: how do homologous sequences get together for recombination?, Nat Rev Genet, vol.9, pp.27-37, 2008. ,
The budding yeast nucleus, Cold Spring Harb Perspect Biol, vol.2, p.612, 2010. ,
Principles of chromosomal organization: lessons from yeast, J Cell Biol, vol.192, pp.723-733, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02079552
High-resolution statistical mapping reveals gene territories in live yeast, Nat Methods, vol.5, pp.1031-1037, 2008. ,
Systematic characterization of the conformation and dynamics of budding yeast chromosome XII, J Cell Biol, vol.202, pp.201-211, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01682609
Chromosome territories, Cold Spring Harb Perspect Biol, vol.2, p.3889, 2010. ,
Chromosome arm length and nuclear constraints determine the dynamic relationship of yeast subtelomeres, Proc Natl Acad Sci, vol.107, pp.2025-2055, 2010. ,
Systematic characterization of the conformation and dynamics of budding yeast chromosome XII, J Cell Biol, vol.202, pp.201-211, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01682609
, Rabl Cerng C ? uber Zellteilung. Morphol Jahrb, vol.10, pp.214-330, 1885.
Genetic and epigenetic control of the spatial organization of the genome, Mol Biol Cell, vol.28, pp.364-369, 2017. ,
Interphase chromosomes undergo constrained diffusional motion in living cells, Curr Biol, vol.7, issue.06, p.412, 1997. ,
, Chromosome Dynamics in the Yeast Interphase Nucleus. Science, vol.294, pp.2181-2186, 2001.
SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope, Nature, vol.441, pp.770-773, 2006. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00207343
High-throughput chromatin motion tracking in living yeast reveals the flexibility of the fiber throughout the genome, Genome Res, vol.23, pp.1829-1867, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01053149
Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage, Mol Biol Cell, 2017. ,
Correlations of three-dimensional motion of chromosomal loci in yeast revealed by the Double-Helix Point Spread Function microscope, Mol Biol Cell, vol.25, pp.3619-3629, 2014. ,
Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates, Nat Struct Mol Biol, vol.24, pp.99-107, 2017. ,
Chromatin stiffening underlies enhanced locus mobility after DNA damage in budding yeast, EMBO J, vol.36, pp.2595-2603, 2017. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02078756
Longrange directional movement of an interphase chromosome site, Curr Biol, vol.16, pp.825-831, 2006. ,
Interchromosomal homology searches drive directional ALT telomere movement and synapsis, Cell, vol.159, pp.108-121, 2014. ,
Centromere tethering confines chromosome domains, Mol Cell, vol.52, pp.819-850, 2013. ,
How to build a yeast nucleus, Nucleus, vol.4, issue.5, pp.361-366, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02079519
Bacterial Chromosomal Loci Move Subdiffusively through a Viscoelastic Cytoplasm, Phys Rev Lett, vol.104, p.238102, 2010. ,
The positioning and dynamics of origins of replication in the budding yeast nucleus, J Cell Biol, vol.152, pp.385-400, 2001. ,
Nonthermal ATPdependent fluctuations contribute to the in vivo motion of chromosomal loci, Proc Natl Acad Sci U S A, vol.109, pp.7338-7381, 2012. ,
Evidence for a dual role of actin in regulating chromosome organization and dynamics in yeast, J Cell Sci, vol.129, pp.681-692, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01419905
Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage, Mol Biol Cell, vol.28, pp.1701-1711, 2017. ,
A three-dimensional model of the yeast genome, Nature, vol.465, pp.363-367, 2010. ,
Filling annotation gaps in yeast genomes using genome-wide contact maps, Bioinformatics, vol.30, pp.2105-2113, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01488132
The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer, Cell Rep, vol.13, pp.1855-1867, 2015. ,
Computational Models of LargeScale Genome Architecture, International Review of Cell and Molecular Biology, vol.307, pp.275-349, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02079507
Bridging the resolution gap in structural modeling of 3D genome organization, PLoS Comput Biol, vol.7, 2011. ,
A Predictive Computational Model of the Dynamic 3D Interphase Yeast Nucleus, Curr Biol, vol.22, pp.1881-90, 2012. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01420017
Physical tethering and volume exclusion determine higher-order genome organization in budding yeast, Genome Res, vol.22, pp.1295-305, 2012. ,
Effect of chromosome tethering on nuclear organization in yeast, PLoS One, vol.9, p.102474, 2014. ,
Dynamical Modeling of Three-Dimensional Genome Organization in Interphase Budding Yeast, Biophys J, vol.102, pp.296-304, 2012. ,
Inferring the physical properties of yeast chromatin through Bayesian analysis of whole nucleus simulations, Genome Biol, vol.18, p.81, 2017. ,
URL : https://hal.archives-ouvertes.fr/inserm-01517883
Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo, Mol Biol Cell, vol.27, pp.3357-3368, 2016. ,
Chromosome position determines the success of double-strand break repair, Proc Natl Acad Sci U S A, vol.113, pp.146-54, 2016. ,
Recombination at subtelomeres is regulated by physical distance, doubleÀstrand break resection and chromatin status, EMBO J, vol.36, issue.17, pp.2609-2634, 2017. ,
Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex, Curr Biol, vol.14, pp.2107-2119, 2004. ,
DNA breaks promote genomic instability by impeding proper chromosome segregation, Curr Biol, vol.14, pp.2096-106, 2004. ,
Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae, PLOS Genet, vol.12, p.1005976, 2016. ,
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break, Curr Biol, vol.14, pp.1703-1711, 2004. ,
Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break, Nat Struct Mol Biol, vol.21, pp.103-109, 2013. ,
Monitoring Homology Search during DNA Double-Strand Break Repair In Vivo, Mol Cell, vol.50, pp.261-272, 2013. ,
Mapping in vivo chromatin interactions in yeast suggests an extended chromatin fiber with regional variation in compaction, J Biol Chem, vol.283, pp.34532-34572, 2008. ,
Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery, Nat Cell Biol, vol.14, pp.502-509, 2012. ,
Increased chromosome mobility facilitates homology search during recombination, Nat Cell Biol, vol.14, pp.510-517, 2012. ,
DNA damage signalling targets the kinetochore to promote chromatin mobility, Nat Cell Biol, vol.18, pp.281-290, 2016. ,
Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage, Mol Biol Cell, vol.28, pp.3323-3355, 2017. ,
DNA Dynamics during Early Double-Strand Break Processing Revealed by ,
URL : https://hal.archives-ouvertes.fr/hal-01117870
, Non-Intrusive Imaging of Living Cells, PLoS Genet, vol.10, p.1004187, 2014.
Remodelers move chromatin in response to DNA damage, Cell Cycle, vol.13, pp.877-885, 2014. ,
Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage, Mol Biol Cell, vol.28, pp.1701-1711, 2017. ,
DNA in motion during double-strand break repair, Trends Cell Biol, vol.23, pp.529-565, 2013. ,
Analysis of Single Locus Trajectories for Extracting In Vivo Chromatin Tethering Interactions, PLOS Comput Biol, vol.11, p.1004433, 2015. ,
Oxford University Press, 2003. ,