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G. Eberl, M. Colonna, D. Santo, J. P. Mckenzie, and A. , Innate lymphoid cells: a new paradigm in immunology, Science, vol.348, p.6566, 2015.
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D. Artis and H. Spits, The biology of innate lymphoid cells, Nature, vol.517, pp.293-301, 2015.

G. F. Sonnenberg and D. Artis, Innate lymphoid cells in the initiation, regulation and resolution of inflammation, Nat Med, vol.21, pp.698-708, 2015.

A. Diefenbach, Innate lymphoid cells in the defense against infections, Eur J Microbiol Immunol, vol.3, pp.143-151, 2013.

N. Serafini, C. Vosshenrich, D. Santo, and J. P. , Transcriptional regulation of innate lymphoid cell fate, Nat. Rev. Immunol, vol.15, pp.415-428, 2015.
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C. Klose, M. Flach, L. Möhle, L. Rogell, T. Hoyler et al., Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages, Cell, vol.157, pp.340-356, 2014.

M. G. Constantinides, B. D. Mcdonald, P. A. Verhoef, and A. Bendelac, A committed precursor to innate lymphoid cells, Nature, vol.508, pp.397-401, 2014.

*. *. Yang, Q. Li, F. Harly, C. Xing, S. Ye et al., TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow, Nat. Immunol, vol.16, pp.1044-1050, 2015.

, This report describes EILP that are multipotent ILCP for NK cells and all ILC subsets

C. R. Seehus, P. Aliahmad, B. De-la-torre, I. D. Iliev, L. Spurka et al., The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor, Nat. Immunol, vol.16, pp.599-608, 2015.

W. Xu, R. G. Domingues, D. Fonseca-pereira, M. Ferreira, H. Ribeiro et al., NFIL3 orchestrates the emergence of common helper innate lymphoid cell precursors, Cell Rep, vol.10, pp.2043-2054, 2015.
URL : https://hal.archives-ouvertes.fr/pasteur-01138721

M. Cherrier, S. Sawa, and G. Eberl, Notch, Id2, and ROR?t sequentially orchestrate the fetal development of lymphoid tissue inducer cells, J. Exp. Med, vol.209, pp.729-740, 2012.

J. S. Lee, M. Cella, K. G. Mcdonald, C. Garlanda, G. D. Kennedy et al., AHR drives the development of gut specified progenitors of group 3 ROR?t(+) innate lymphoid cells, Immunity, vol.41, pp.988-1000, 2014.

*. *. Scoville, S. D. Mundy-bosse, B. L. Zhang, M. H. Chen, L. Zhang et al., A Progenitor Cell Expressing Transcription Factor ROR?t Generates All Human Innate Lymphoid Cell Subsets, Immunity, vol.44, pp.1140-1150, 2016.

, This report identifies RORgT + ILC precursors in human secondary lymphoid tissues that have capacity to develop into NK cells and ILC subsets in vitro

*. *. Ter-horst, R. Jaeger, M. Smeekens, S. P. Oosting, M. Swertz et al., Host and Environmental Factors Influencing Individual Human Cytokine Responses, Cell, vol.167, pp.1111-1124, 2016.

*. Duffy, D. Rouilly, V. Libri, V. Hasan, M. Beitz et al., Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli, Immunity, vol.40, pp.436-450, 2014.
URL : https://hal.archives-ouvertes.fr/pasteur-01384537

, With 25**, a set of resource papers describing the genetic control of whole blood immune responses in normal individuals

S. I. Samson, O. Richard, M. Tavian, T. Ranson, C. Vosshenrich et al., GATA-3 promotes maturation, IFN-gamma production, and liver-specific homing of NK cells, Immunity, vol.19, pp.701-711, 2003.

R. Yagi, C. Zhong, D. L. Northrup, F. Yu, N. Bouladoux et al., The transcription factor GATA3 is critical for the development of all IL-7R?-expressing innate lymphoid cells, Immunity, vol.40, pp.378-388, 2014.

N. Serafini, R. Klein-wolterink, N. Satoh-takayama, W. Xu, C. Vosshenrich et al., Gata3 drives development of ROR?t+ group 3 innate lymphoid cells, J. Exp. Med, vol.211, pp.199-208, 2014.

R. Klein-wolterink, N. Serafini, M. Van-nimwegen, C. Vosshenrich, M. De-bruijn et al., Essential, dosedependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells, Proc. Natl. Acad. Sci. U.S.A, vol.110, pp.10240-10245, 2013.
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C. Vosshenrich, M. E. García-ojeda, S. I. Samson-villéger, V. Pasqualetto, L. Enault et al., A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127, Nat. Immunol, vol.7, pp.1217-1224, 2006.
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D. K. Sojka, B. Plougastel-douglas, L. Yang, M. A. Pak-wittel, M. N. Artyomov et al., Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells, vol.3, p.1659, 2014.
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S. M. Gordon, J. Chaix, L. J. Rupp, J. Wu, S. Madera et al., The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation, Immunity, vol.36, pp.55-67, 2012.

*. *. Gasteiger, G. , F. X. Dikiy, S. Lee, S. Y. Rudensky et al., Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs, Science, vol.350, pp.981-985, 2015.

, A report demonstrating that ILC are tissue-resident immune effector cells that represent innate versions of tissue memory T cells

J. M. Schenkel and D. Masopust, Tissue-Resident Memory T Cells. Immunity, vol.41, pp.886-897, 2014.

H. Spits and J. H. Bernink, Lanier L: NK cells and type 1 innate lymphoid cells: partners in host defense, Nat Immunol, vol.17, pp.758-764, 2016.
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K. Takeda, E. Cretney, Y. Hayakawa, T. Ota, H. Akiba et al., TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver, Blood, vol.105, pp.2082-2091, 2005.
DOI : 10.1182/blood-2004-08-3262
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C. Daussy, F. Faure, K. Mayol, S. Viel, G. Gasteiger et al., T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow, J. Exp. Med, vol.211, pp.563-77, 2014.
URL : https://hal.archives-ouvertes.fr/hal-00972070

D. K. Sojka, Z. Tian, and W. M. Yokoyama, Tissue-Resident Natural Killer Cells and Their Potential Diversity, Semin Immunol, vol.26, pp.127-131, 2014.
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*. Pikovskaya, O. Chaix, J. Rothman, N. J. Collins, A. Chen et al., Cutting Edge: Eomesodermin Is Sufficient To Direct Type 1 Innate Lymphocyte Development into the Conventional NK Lineage, J. Immunol, vol.196, pp.1449-1454, 2016.
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URL : https://hal.archives-ouvertes.fr/hal-01438533

, Evidence that enforced Eomes expression can regulate ILC1 to NK cell plasticity

C. Harmon, M. W. Robinson, R. Fahey, S. Whelan, D. D. Houlihan et al., Tissue-resident Eomes(hi) T-bet(lo) CD56(bright) NK cells with reduced proinflammatory potential are enriched in the adult human liver, Eur. J. Immunol, vol.46, pp.2111-2120, 2016.

*. Stegmann, K. A. Robertson, F. Hansi, N. Gill, U. Pallant et al., CXCR6 marks a novel subset of Tbet(lo)Eomes(hi) natural killer cells residing in human liver, Sci Rep, vol.6, p.26157, 2016.

, With 41*, the identification of unusual EOMES + liver-resident ILC1 subsets in humans

*. *. Mackay, L. K. Minnich, M. Kragten, N. Liao, Y. Nota et al., Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes, Science, vol.352, pp.459-463, 2016.

*. *. Hombrink, P. Helbig, C. Backer, R. A. Piet, B. Oja et al., Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells, Nat. Immunol, 2016.

, With 43**, characterization of transcription factors and their targets that drive tissueresidency of mouse and human T cells

*. *. Cortez, V. S. Cervantes-barragan, L. Robinette, M. L. Bando, J. K. Wang et al., Transforming Growth Factor-? Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands, Immunity, vol.44, pp.1127-1139, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01438538

, A report identifying TGFb as a critical determinant of ILC1 phenotypes in non-lymphoid tissues

T. Halim, A. Maclaren, M. T. Romanish, M. J. Gold, K. M. Mcnagny et al., Retinoicacid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation, Immunity, vol.37, pp.463-474, 2012.

C. J. Spooner, J. Lesch, D. Yan, A. A. Khan, A. Abbas et al., Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1, Nat. Immunol, vol.14, pp.1229-1236, 2013.

I. Tindemans, N. Serafini, D. Santo, J. P. Hendriks, and R. W. , GATA-3 function in innate and adaptive immunity, Immunity, vol.41, pp.191-206, 2014.
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*. *. Antignano, F. Braam, M. Hughes, M. R. Chenery, A. L. Burrows et al., G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program, J. Exp. Med, vol.213, pp.1153-1162, 2016.

, First description of an epigenetic modifier that controls ILC development

M. Bonelli, H. Shih, K. Hirahara, K. Singelton, A. Laurence et al., Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes, Curr. Top. Microbiol. Immunol, vol.381, pp.279-326, 2014.

S. L. Gaffen, R. Jain, A. V. Garg, and D. J. Cua, The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing, Nat. Rev. Immunol, vol.14, pp.585-600, 2014.

C. Vonarbourg, A. Mortha, V. L. Bui, P. P. Hernandez, E. A. Kiss et al., Regulated expression of nuclear receptor ROR?t confers distinct functional fates to NK cell receptor-expressing ROR?t(+) innate lymphocytes, Immunity, vol.33, pp.736-751, 2010.

J. H. Bernink, C. P. Peters, M. Munneke, A. A. Te-velde, S. L. Meijer et al., Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues, Nat. Immunol, vol.14, pp.221-229, 2013.

J. H. Bernink, L. Krabbendam, K. Germar, J. E. De, K. Gronke et al.,

, Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria, Control Plasticity of CD127(+), vol.43, pp.146-160, 2015.

*. Verrier, T. Satoh-takayama, N. Serafini, N. , M. S. et al., Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group, vol.3
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, Innate Lymphoid Cells. J. Immunol, vol.196, pp.4731-4738, 2016.

*. Viant, C. Rankin, L. C. Girard-madoux, M. Seillet, C. Shi et al., Transforming growth factor-? and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells, Sci Signal, vol.9, p.46, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01438546

, With 55*, a description of phenotypic and functional plasticity in mouse intestinal ILC3 subsets that have lost NKp46 expression

S. M. Bal, J. H. Bernink, M. Nagasawa, J. Groot, M. M. Shikhagaie et al., IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs, Nat. Immunol, vol.17, pp.636-645, 2016.

, See also 58**, 59**, 60**

*. *. Silver, J. S. Kearley, J. Copenhaver, A. M. Sanden, C. Mori et al., Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs, Nat. Immunol, vol.17, pp.626-635, 2016.

, See also 57**, 59**, 60**

*. *. Ohne, Y. Silver, J. S. Thompson-snipes, L. Collet, M. A. Blanck et al., IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity, Nat. Immunol, vol.17, pp.646-655, 2016.

, See also 57**, 58**, 60**

*. *. Lim, A. I. Menegatti, S. Bustamante, J. , L. Bourhis et al., IL-12 drives functional plasticity of human group 2 innate lymphoid cells, J. Exp. Med, vol.213, pp.569-583, 2016.

, With 57**, 58** and 59**, a series of reports describing ILC2 plasticity in humans and mice characterized by a transition to ILC1-like phenotypes in inflamed tissues

*. *. Koues, O. I. Collins, P. L. Cella, M. Robinette, M. L. Porter et al., Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells, Cell, vol.165, pp.1134-1146, 2016.

, See also 62**, vol.63

H. Shih, G. Sciumè, Y. Mikami, L. Guo, H. Sun et al., Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality, vol.165, pp.1120-1133, 2016.

, See also 61**, vol.63

M. Gury-benari, C. A. Thaiss, N. Serafini, D. R. Winter, A. Giladi et al., The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome, Cell, vol.166, pp.1231-1246, 2016.

, With 61** and 62** a series of reports describing the regulomes and transcriptomes of human and mouse ILC subsets by ATACseq, histone ChIPseq and RNAseq approahes