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Journal articles
Mitotic bookmarking in development and stem cells
Abstract : The changes imposed on the nucleus, chromatin and its regulators during mitosis lead to the dismantlement of most gene regulatory processes. However, an increasing number of transcriptional regulators are being identified as capable of binding their genomic targets during mitosis. These so-called 'mitotic bookmarking factors' encompass transcription factors and chromatin modifiers that are believed to convey gene regulatory information from mother to daughter cells. In this Primer, we review mitotic bookmarking processes in development and stem cells and discuss the interest and potential importance of this concept with regard to epigenetic regulation and cell fate transitions involving cellular proliferation.
Cited literature [130 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-02024822
Contributor : Floran Bidault <>
Submitted on : Tuesday, February 19, 2019 - 1:23:15 PM
Last modification on : Tuesday, June 30, 2020 - 5:08:02 PM
Long-term archiving on: : Monday, May 20, 2019 - 4:18:31 PM
Contributor : Floran Bidault <>
Submitted on : Tuesday, February 19, 2019 - 1:23:15 PM
Last modification on : Tuesday, June 30, 2020 - 5:08:02 PM
Long-term archiving on: : Monday, May 20, 2019 - 4:18:31 PM
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