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DNA Synthesis by Primer Exchange Reaction Cascades

Abstract : Swap and extend: The autonomous synthesis of single-stranded DNA molecules of arbitrary size and sequence composition can easily be achieved by primer exchange reaction (PER) cascades, in which the sequential polymerase-mediated extension of DNA primers is guided by catalytic hairpins. This highlight illustrates the potential of this method for applications in DNA nanotechnology.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-02012260
Contributor : Marcel Hollenstein <>
Submitted on : Friday, February 8, 2019 - 3:52:50 PM
Last modification on : Monday, January 13, 2020 - 5:08:19 PM

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Marcel Hollenstein. DNA Synthesis by Primer Exchange Reaction Cascades. ChemBioChem, Wiley-VCH Verlag, 2018, 19 (5), pp.422-424. ⟨10.1002/cbic.201700639⟩. ⟨pasteur-02012260⟩

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