Abstract : Releasing mosquitoes infected with the intracellular bacteria Wolbachia is a candidate strategy for dengue control that has recently advanced to field-testing. A critical next step is to evaluate the impact of this strategy on dengue epidemiology. A recent study by Ferguson and colleagues presents a mathematical framework to predict the likely effect of mosquitoes carrying Wolbachia on dengue virus transmission. Fitting the mathematical model to empirical data obtained with Wolbachia-infected mosquitoes experimentally challenged with viremic blood from dengue patients indicates that dengue virus transmission could be reduced by a degree that would have a significant impact on public health.
https://hal-pasteur.archives-ouvertes.fr/pasteur-02011023 Contributor : Fanny SEBIREConnect in order to contact the contributor Submitted on : Friday, February 8, 2019 - 2:02:37 PM Last modification on : Thursday, April 7, 2022 - 10:10:36 AM Long-term archiving on: : Thursday, May 9, 2019 - 2:22:39 PM
Louis A Lambrechts. Predicting Wolbachia potential to knock down dengue virus transmission. Annals of translational medicine, AME Publishing Company, 2015, 3 (19), pp.288. ⟨10.3978/j.issn.2305-5839.2015.09.33⟩. ⟨pasteur-02011023⟩