Skip to Main content Skip to Navigation
New interface
Journal articles

Reduction of Aedes aegypti vector competence for dengue virus under large temperature fluctuations

Abstract : Diurnal temperature fluctuations can fundamentally alter mosquito biology and mosquito-virus interactions in ways that impact pathogen transmission. We investigated the effect of two daily fluctuating temperature profiles on Aedes aegypti vector competence for dengue virus (DENV) serotype-1. A large diurnal temperature range of 18.6°C around a 26°C mean, corresponding with the low DENV transmission season in northwestern Thailand, reduced midgut infection rates and tended to extend the virus extrinsic incubation period. Dissemination was first observed at day 7 under small fluctuations (7.6°C; corresponding with high DENV transmission) and constant control temperature, but not until Day 11 for the large diurnal temperature range. Results indicate that female Ae. aegypti in northwest Thailand are less likely to transmit DENV during the low than high transmission season because of reduced DENV susceptibility and extended virus extrinsic incubation period. Better understanding of DENV transmission dynamics will come with improved knowledge of temperature effects on mosquito-virus interactions.
Document type :
Journal articles
Complete list of metadata

Cited literature [1 references]  Display  Hide  Download
Contributor : Fanny SEBIRE Connect in order to contact the contributor
Submitted on : Friday, February 8, 2019 - 2:25:13 PM
Last modification on : Tuesday, November 29, 2022 - 11:56:14 AM
Long-term archiving on: : Thursday, May 9, 2019 - 2:29:01 PM


Files produced by the author(s)


Distributed under a Creative Commons Attribution 4.0 International License




Lauren B. Carrington, Stephanie N. Seifert, M. Veronica Armijos, Louis A Lambrechts, Thomas W. Scott. Reduction of Aedes aegypti vector competence for dengue virus under large temperature fluctuations. American Journal of Tropical Medicine and Hygiene, 2013, 88 (4), pp.689-697. ⟨10.4269/ajtmh.12-0488⟩. ⟨pasteur-02011020⟩



Record views


Files downloads