Human Adaptation of Ebola Virus during the West African Outbreak
Abstract
Graphical Abstract Highlights d EBOV adapted to humans during the West African outbreak d Amino acid substitutions in the EBOV glycoprotein increase human cell tropism d The same glycoprotein amino acid substitutions decrease tropism for bat cells In Brief The Ebola virus acquired amino acid substitutions in its glycoprotein that increased its tropism for human cells during the West African outbreak of 2013-2016.
Domains
Computer Science [cs] Bioinformatics [q-bio.QM] Life Sciences [q-bio] Quantitative Methods [q-bio.QM] Life Sciences [q-bio] Genetics Human genetics Life Sciences [q-bio] Genetics Populations and Evolution [q-bio.PE] Life Sciences [q-bio] Microbiology and Parasitology Virology Life Sciences [q-bio] Microbiology and Parasitology Parasitology Life Sciences [q-bio] Santé publique et épidémiologie
Origin : Publication funded by an institution
Loading...