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Journal articles
Protein-protein interactions leading to recruitment of the host DNA sliding clamp by the hyperthermophilic Sulfolobus islandicus rod-shaped virus 2
Abstract : Viruses infecting hyperthermophilic archaea typically do not encode DNA polymerases, raising questions regarding their genome replication. Here, using a yeast two-hybrid approach, we have assessed interactions between proteins of Sulfolobus islandicus rod-shaped virus 2 (SIRV2) and the host-encoded proliferating cell nuclear antigen (PCNA), a key DNA replication protein in archaea. Five SIRV2 proteins were found to interact with PCNA, providing insights into the recruitment of host replisome for viral DNA replication.
Cited literature [35 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01977399
Contributor : Floran Bidault <>
Submitted on : Thursday, January 10, 2019 - 4:55:51 PM
Last modification on : Tuesday, October 20, 2020 - 1:04:02 PM
Long-term archiving on: : Thursday, April 11, 2019 - 5:42:59 PM
Contributor : Floran Bidault <>
Submitted on : Thursday, January 10, 2019 - 4:55:51 PM
Last modification on : Tuesday, October 20, 2020 - 1:04:02 PM
Long-term archiving on: : Thursday, April 11, 2019 - 5:42:59 PM