A. G. Smith, Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides, Nature, vol.336, pp.688-690, 1988.

J. Kim, J. Chu, X. Shen, J. Wang, and S. H. Orkin, An extended transcriptional network for pluripotency of embryonic stem cells, Cell, vol.132, pp.1049-1061, 2008.

X. Chen, Integration of external signaling pathways with the core transcriptional network in embryonic stem cells, Cell, vol.133, pp.1106-1117, 2008.

I. Chambers, Nanog safeguards pluripotency and mediates germline development, Nature, vol.450, pp.1230-1234, 2007.
DOI : 10.1038/nature06403

J. Nichols, Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4, Cell, vol.95, pp.379-391, 1998.

H. Niwa, J. Miyazaki, and A. G. Smith, Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells, Nature genetics, vol.24, pp.372-376, 2000.

S. Masui, Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells, Nat Cell Biol, vol.9, pp.625-635, 2007.

N. Festuccia, Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells, Cell stem cell, vol.11, pp.477-490, 2012.

G. Martello, Esrrb is a pivotal target of the gsk3/tcf3 axis regulating embryonic stem cell self-renewal, Cell Stem Cell, vol.11, pp.491-504, 2012.

J. L. Kopp, B. D. Ormsbee, M. Desler, and A. Rizzino, Small increases in the level of Sox2 trigger the differentiation of mouse embryonic stem cells, Stem Cells, vol.26, pp.903-911, 2008.

I. Chambers, Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells, Cell, vol.113, pp.643-655, 2003.

E. Stead, Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities, Oncogene, vol.21, pp.8320-8333, 2002.

J. White, Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation, Mol Biol Cell, vol.16, pp.2018-2027, 2005.

R. Faast, Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a), Oncogene, vol.23, pp.491-502, 2004.

S. Dalton, Linking the Cell Cycle to Cell Fate Decisions, Trends Cell Biol, vol.25, pp.592-600, 2015.

M. A. Martinez-balbas, A. Dey, S. K. Rabindran, K. Ozato, and C. Wu, Displacement of sequence-specific transcription factors from mitotic chromatin, Cell, vol.83, pp.29-38, 1995.

A. Tsumura, Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b, Genes Cells, vol.11, pp.805-814, 2006.

M. Leeb, Polycomb complexes act redundantly to repress genomic repeats and genes, Genes Dev, vol.24, pp.265-276, 2010.
DOI : 10.1101/gad.544410
URL : http://genesdev.cshlp.org/content/24/3/265.full.pdf

B. Lehnertz, Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin, Curr Biol, vol.13, pp.1192-1200, 2003.
DOI : 10.1016/s0960-9822(03)00432-9
URL : https://doi.org/10.1016/s0960-9822(03)00432-9

M. Tachibana, G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis, Genes Dev, vol.16, pp.1779-1791, 2002.

A. De-los and A. , Hallmarks of pluripotency, Nature, vol.525, pp.469-478, 2015.

E. F. Michelotti, S. Sanford, and D. Levens, Marking of active genes on mitotic chromosomes, Nature, vol.388, pp.895-899, 1997.

H. Xing, N. L. Vanderford, and K. D. Sarge, The TBP-PP2A mitotic complex bookmarks genes by preventing condensin action, Nature cell biology, vol.10, pp.1318-1323, 2008.

M. D. Gearhart, S. M. Holmbeck, R. M. Evans, H. J. Dyson, and P. E. Wright, Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition, J Mol Biol, vol.327, pp.819-832, 2003.

F. Mueller, T. S. Karpova, D. Mazza, and J. G. Mcnally, Monitoring dynamic binding of chromatin proteins in vivo by fluorescence recovery after photobleaching, Methods Mol Biol, vol.833, pp.153-176, 2012.

D. L. Van-den-berg, Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression, Mol Cell Biol, vol.28, pp.5986-5995, 2008.

F. Halbritter, H. J. Vaidya, and S. R. Tomlinson, GeneProf: analysis of high-throughput sequencing experiments, Nat Methods, vol.9, pp.7-8, 2012.

C. Y. Mclean, GREAT improves functional interpretation of cis-regulatory regions, Nat Biotechnol, vol.28, pp.495-501, 2010.

A. Medina-rivera, Regulatory Sequence Analysis Tools, vol.43, pp.50-56, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01624291

J. G. Madsen, iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data, Nucleic Acids Res, vol.43, p.40, 2015.