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Journal articles
A cryptic subgroup of Anopheles gambiae is highly susceptible to human malaria parasites
Michelle Riehle
1, 2
Wamdaogo Guelbéogo
3
Awa Gneme
3
Karin Eiglmeier
1
Inge Holm
1
Emmanuel Bischoff
1
Thierry Garnier
4
Gregory Snyder
2
Xuanzhong Li
5
Kyriacos Markianos
5
N'Fale Sagnon
3
Kenneth D Vernick
1, *
Xuanzhong Li 5
Author
Kyriacos Markianos 5
Author
N'Fale Sagnon 3
Author
Kenneth D Vernick 1
Correspondent author IdHAL : kenneth-vernick ORCID : https://orcid.org/0000-0003-4336-312X
1
Génétique et Génomique des Insectes vecteurs (Département Parasites et Insectes vecteurs, 25-28, rue du docteur Roux, 75724 Paris Cedex 15 - France)
- Institut Pasteur [Paris] (25-28, rue du docteur Roux, 75724 Paris cedex 15 - France)
- CNRS - Centre National de la Recherche Scientifique : URA3012 (France)
2
UMN - University of Minnesota [Twin Cities] (Minneapolis/St.Paul - United States)
- University of Minnesota System (United States)
3
CNRFP - Centre National de Recherche et de Formation sur le Paludisme [Ouagadougou, Burkina Faso] (BP 2208, Ouagadougou 01 - Burkina Faso)
4
Génétique Moléculaire Bactérienne (28 rue du Docteur Roux, 75724 Paris Cedex 15 - France)
- Institut Pasteur [Paris] (25-28, rue du docteur Roux, 75724 Paris cedex 15 - France)
5
HMS - Harvard Medical School [Boston] (25 Shattuck Street Boston, MA 02115 - United States)
Abstract : Population subgroups of the African malaria vector Anopheles gambiae have not been comprehensively characterized owing to the lack of unbiased sampling methods. In the arid savanna zone of West Africa, where potential oviposition sites are scarce, widespread collection from larval pools in the peridomestic human habitat yielded a comprehensive genetic survey of local A. gambiae population subgroups, independent of adult resting behavior and ecological preference. A previously unknown subgroup of exophilic A. gambiae is sympatric with the known endophilic A. gambiae in this region. The exophilic subgroup is abundant, lacks differentiation into M and S molecular forms, and is highly susceptible to infection with wild Plasmodium falciparum. These findings might have implications for the epidemiology of malaria transmission and control.
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Journal articles
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https://hal-pasteur.archives-ouvertes.fr/pasteur-01971785
Contributor : Kenneth Vernick <>
Submitted on : Monday, January 7, 2019 - 12:32:44 PM
Last modification on : Thursday, June 10, 2021 - 4:08:02 PM
Contributor : Kenneth Vernick <>
Submitted on : Monday, January 7, 2019 - 12:32:44 PM
Last modification on : Thursday, June 10, 2021 - 4:08:02 PM
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- HAL Id : pasteur-01971785, version 1
- DOI : 10.1126/science.1200801
- PUBMED : 21292978
- PUBMEDCENTRAL : PMC3065189
Citation
Michelle Riehle, Wamdaogo Guelbéogo, Awa Gneme, Karin Eiglmeier, Inge Holm, et al.. A cryptic subgroup of Anopheles gambiae is highly susceptible to human malaria parasites. Science, American Association for the Advancement of Science, 2011, 331 (6017), pp.593-596. ⟨10.1126/science.1200801⟩. ⟨pasteur-01971785⟩
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