Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest, Exp Hematol, vol.28, pp.537-540, 2000. ,
SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion, Trends Cell Biol, vol.18, pp.486-93, 2008. ,
Macrophages require Skap2 and Sirp? for integrinstimulated cytoskeletal rearrangement, J Cell Sci, vol.125, pp.5535-5580, 2012. ,
Macrophage colonystimulating factor receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin, Cell Signal, vol.17, pp.941-990, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00192861
SKAP2 Promotes Podosome Formation to Facilitate Tumor-Associated Macrophage Infiltration and Metastatic Progression, Cancer Res, vol.76, pp.358-69, 2016. ,
Regulation of the Src kinase-associated phosphoprotein 55 homologue by the protein tyrosine phosphatase PTP-PEST in the control of cell motility, J Biol Chem, vol.288, pp.25739-25787, 2013. ,
2014: mutations, PTMs and recalibrations, Nucleic Acids Res, vol.43, pp.512-532, 2015. ,
ELM-the database of eukaryotic linear motifs, Nucleic Acids Res, vol.40, pp.242-51, 2012. ,
RA70 is a src kinase-associated protein expressed ubiquitously, Biochem Biophys Res Commun, vol.252, pp.738-780, 1998. ,
SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55, FEBS Lett, vol.435, issue.98, pp.1040-1040, 1998. ,
The Skap-hom dimerization and PH domains comprise a 3?-phosphoinositide-gated molecular switch, Mol Cell, vol.32, pp.564-75, 2008. ,
HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion, PLoS One, vol.5, 2010. ,
Expression of SKAP-HOM in DCs is required for an optimal immune response in vivo, J Leukoc Biol, vol.86, pp.61-71, 2009. ,
Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM ,
, Mol Cell Biol, vol.25, pp.8052-8063, 2005.
SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages, Curr Biol, vol.9, pp.80401-80402, 1999. ,
FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells, Proc Natl Acad Sci USA, vol.95, pp.8779-84, 1998. ,
Identification and characterization of a novel Pyk2/ related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation, J Biol Chem, vol.278, pp.42225-42258, 2003. ,
Src kinase-associated phosphoprotein2 expression is associated with poor prognosis in non-small cell lung cancer, Anticancer Res, vol.35, pp.2411-2426, 2015. ,
SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell, J Cell Mol Med, vol.15, pp.783-95, 2011. ,
Src family kinases: regulation of their activities, levels and identification of new pathways, Biochim Biophys Acta, vol.1784, pp.56-65, 2008. ,
Myristoylation and membrane binding regulate c-Src stability and kinase activity, Mol Cell Biol, vol.30, pp.4094-107, 2010. ,
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain, J Cell Sci, vol.122, pp.965-75, 2009. ,
The Src, Syk, and Tec family kinases: distinct types of molecular switches, Cell Signal, vol.22, pp.1175-84, 2010. ,
Structure and dynamic regulation of Src-family kinases, Cell Mol Life Sci, vol.65, pp.3058-73, 2008. ,
Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors, Pharmacol Res, vol.94, pp.9-25, 2015. ,
Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation, Proc Natl Acad Sci USA, vol.85, pp.4232-4268, 1988. ,
Crystal structure of Hck in complex with a Src familyselective tyrosine kinase inhibitor, Mol Cell, vol.3, pp.80357-80360, 1999. ,
Crystal structure of the Src family tyrosine kinase Hck, Nature, vol.385, pp.602-611, 1997. ,
Multidomain assembled states of Hck tyrosine kinase in solution, Proc Natl Acad Sci USA, vol.107, pp.15757-62, 2010. ,
Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells, Oncotarget, vol.6, pp.15752-71, 2015. ,
Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis, Cell Res, vol.23, pp.524-560, 2013. ,
Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1, Mol Endocrinol, vol.18, pp.402-413, 2004. ,
Benchmarking a luciferase complementation assay for detecting protein complexes, Nat Methods, vol.8, pp.990-92, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01971619
Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant www.impactjournals.com/oncotarget activation mechanism, J Biol Chem, vol.285, pp.35455-61, 2010. ,
Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity, Structure, vol.24, pp.1947-1959, 2016. ,
Dynamics-Driven Allostery in Protein Kinases, Trends Biochem Sci, vol.40, pp.628-675, 2015. ,
DOI : 10.1016/j.tibs.2015.09.002
URL : http://europepmc.org/articles/pmc4630092?pdf=render
HaloTag: a novel protein labeling technology for cell imaging and protein analysis, ACS Chem Biol, vol.3, pp.373-82, 2008. ,
DOI : 10.1021/cb800025k
URL : http://www.qub.ac.uk/mlpage/courses/level3/meb/halotagcb800025k.pdf
Solution structure of the SH3 domain of Src and identification of its ligand-binding site, Science, vol.258, pp.1665-68, 1992. ,
Analysis of Phosphorylation-dependent Protein Interactions of Adhesion and Degranulation Promoting Adaptor Protein (ADAP) Reveals Novel Interaction Partners Required for Chemokine-directed T cell Migration, Mol Cell Proteomics, vol.14, pp.2961-72, 2015. ,
The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation, Oncogene, vol.5, pp.1455-62, 1990. ,
A proteomescale map of the human interactome network, Cell, vol.159, pp.1212-1238, 2014. ,
Src kinase activation by direct interaction with the integrin beta cytoplasmic domain, Proc Natl Acad Sci USA, vol.100, pp.13298-302, 2003. ,
DOI : 10.1073/pnas.2336149100
URL : http://www.pnas.org/content/100/23/13298.full.pdf
COSMIC: somatic cancer genetics at high-resolution, Nucleic Acids Res, vol.45, pp.777-783, 2017. ,
DOI : 10.1093/nar/gkw1121
URL : https://academic.oup.com/nar/article-pdf/45/D1/D777/8846917/gkw1121.pdf
Structural Basis for the Non-catalytic Functions of Protein Kinases, Structure, vol.24, pp.7-24, 2016. ,
, R: A Language and Environment for Statistical Computing, the R Foundation for Statistical Computing, 2011.
Cytoscape: a software environment for integrated models of biomolecular interaction networks, Genome Res, vol.13, pp.2498-504, 2003. ,