8IMVA - U1184 - Immunologie des Maladies Virales et Autoimmunes (Site de l'Hôpital de Bicêtre - Faculté de Médecine Paris Sud - 63 rue Gabriel Péri 94276 Le Kremlin-Bicêtre Cedex.
Site du CEA de Fontenay-aux-Roses - 10, route du Panorama - BP 6 - 92265 Fontenay-aux-Roses. - France)
Abstract : Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class and virulence mechanisms of the pathogen, the stage of the disease, and the pathology associated with the infection. This work compiles evidence supported by functional assays on the roles of different subsets of MDSCs in acute and chronic infections, including pathogen-associated malignancies, and discusses strategies to modulate MDSC dynamics to benefit the host.
https://hal-pasteur.archives-ouvertes.fr/pasteur-01969805 Contributor : Brigitte BIDAULTConnect in order to contact the contributor Submitted on : Friday, January 4, 2019 - 3:12:59 PM Last modification on : Sunday, June 26, 2022 - 12:10:35 PM Long-term archiving on: : Friday, April 5, 2019 - 2:21:11 PM