The chlamydial developmental cycle, FEMS Microbiol. Rev, vol.29, pp.949-959, 2005. ,
PHENIX: a comprehensive Python-based system for macromolecular structure solution, Acta Crystallogr. Sec. D Biol. Crystallogr, vol.66, pp.213-221, 2010. ,
PHENIX: building new software for automated crystallographic structure determination, Acta Crystallogr. Sec. D Biol. Crystallogr, vol.58, pp.1948-1954, 2002. ,
Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome, Nucleic Acids Res, vol.38, pp.868-877, 2010. ,
MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins, Mol. Microbiol, vol.7, pp.59-68, 1993. ,
Hypothetical protein CT398 (CdsZ) interacts with sigma(54) (RpoN)-holoenzyme and the type III secretion export apparatus in Chlamydia trachomatis, Protein Sci, vol.24, pp.1617-1632, 2015. ,
Expression and targeting of secreted proteins from Chlamydia trachomatis, J. Bacteriol, vol.196, pp.1325-1334, 2014. ,
Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis, Proc. Natl. Acad. Sci. U.S.A, vol.100, pp.8478-8483, 2003. ,
Chlamydia trachomatis serovar L2 induces protein tyrosine phosphorylation during uptake by HeLa cells, Infect. Immun, vol.62, pp.4900-4908, 1994. ,
Chaperone-assisted production of active human Rab8A GTPase in Escherichia coli, Protein Expr. Purif, vol.65, pp.190-195, 2009. ,
Chlamydia trachomatis Slc1 is a type III secretion chaperone that enhances the translocation of its invasion effector substrate TARP, Mol. Microbiol, vol.82, pp.131-144, 2011. ,
Immunology of Chlamydia infection: Implications for a Chlamydia trachomatis vaccine, Nat. Rev. Immunol, vol.5, pp.149-161, 2005. ,
Scalable web services for the PSIPRED protein analysis workbench, Nucleic Acids Res, vol.41, pp.349-357, 2013. ,
The effector TepP mediates recruitment and activation of phosphoinositide 3-kinase on early Chlamydia trachomatis vacuoles, vol.2, pp.207-224, 2017. ,
The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling, PLoS Pathog, vol.10, p.1003954, 2014. ,
, , 2004.
, A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin, Proc. Natl. Acad. Sci. U.S.A, vol.101, pp.10166-10171
, The CCP4 suite: programs for protein crystallography, Acta Crystallogr. D. Biol. Crystallogr, vol.50, pp.760-763, 1994.
One face of Chlamydia trachomatis: the infectious elementary body, Curr. Top. Microbiol. Immunol, 2016. ,
Identification of type III secretion substrates of Chlamydia trachomatis using Yersinia enterocolitica as a heterologous system, BMC Microbiol, vol.14, p.40, 2014. ,
Production of selenomethionyl proteins in prokaryotic and eukaryotic expression systems, Methods Mol. Biol, vol.363, pp.91-108, 2007. ,
Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids, J. Am. Chem. Soc, vol.128, pp.2822-2835, 2006. ,
Coot: model-building tools for molecular graphics, Acta Crystallogr. D. Biol. Crystallogr, vol.60, pp.2126-2132, 2004. ,
Features and development of Coot, Acta Crystallogr. D. Biol. Crystallogr, vol.66, pp.486-501, 2010. ,
Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity, J. Bacteriol, vol.195, pp.506-519, 2013. ,
An introduction to data reduction: space-group determination, scaling and intensity statistics, Acta Crystallogr. D. Biol. Crystallogr, vol.67, pp.282-292, 2011. ,
Infection with Chlamydia trachomatis alters the tyrosine phosphorylation and/or localization of several host cell proteins including cortactin, Infect. Immun, vol.65, pp.5301-5308, 1997. ,
A working model for the type III secretion mechanism in Chlamydia. Microbes Infect, vol.18, pp.84-92, 2016. ,
CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis, Proc. Natl. Acad. Sci. U.S.A, vol.98, pp.1160-1165, 2001. ,
DOI : 10.1073/pnas.98.3.1160
URL : http://www.pnas.org/content/98/3/1160.full.pdf
Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells, Annu. Rev. Microbiol, vol.68, pp.415-438, 2014. ,
Sequestration of host metabolism by an intracellular pathogen, Elife, vol.5, p.12552, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01397781
An optimized system for expression and purification of secreted bacterial proteins, Protein Expr. Purif, vol.46, pp.23-32, 2006. ,
DOI : 10.1016/j.pep.2005.09.003
Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1, Microbiology, vol.157, pp.1134-1144, 2011. ,
ESPript: analysis of multiple sequence alignments in PostScript, Bioinformatics, vol.15, pp.305-308, 1999. ,
URL : https://hal.archives-ouvertes.fr/hal-00314288
Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing, Nat. Genet, vol.44, pp.413-419, 2012. ,
DOI : 10.1038/ng.2214
URL : http://researchonline.lshtm.ac.uk/26747/1/ng.2214.pdf
Using Dali for structural comparison of proteins, Curr. Protoc. Bioinformatics, vol.5, 2006. ,
DOI : 10.1002/0471250953.bi0505s14
Dali server: conservation mapping in 3D, Nucleic Acids Res, vol.38, pp.545-549, 2010. ,
DOI : 10.1093/nar/gkq366
URL : https://academic.oup.com/nar/article-pdf/38/suppl_2/W545/16772546/gkq366.pdf
Site-Specific, insertional inactivation of incA in Chlamydia trachomatis using a group II intron, PLoS ONE, vol.8, p.83989, 2013. ,
, XDS. Acta Crystallogr. D. Biol. Crystallogr, vol.66, pp.125-132, 2010.
Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations, J. Infect. Dis, vol.197, pp.449-456, 2008. ,
Chain elongation in the isoprenoid biosynthetic pathway, Curr. Opin. Chem. Biol, vol.1, pp.570-578, 1997. ,
Use of aminoglycoside 3' adenyltransferase as a selection marker for Chlamydia trachomatis intron-mutagenesis and in vivo intron stability, BMC Res. Notes, vol.8, p.570, 2015. ,
Phylogenetic analysis of Chlamydia trachomatis Tarp and correlation with clinical phenotype, Infect. Immun, vol.78, pp.3678-3688, 2010. ,
Fluorescencereported allelic exchange mutagenesis reveals a role for Chlamydia trachomatis TmeA in invasion that is independent of host AHNAK, Infect. Immun, vol.85, pp.640-657, 2017. ,
Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells, J. Bacteriol, vol.175, pp.5899-5906, 1993. ,
Application of ?-lactamase reporter fusions as an indicator of effector protein secretion during infections with the obligate intracellular pathogen Chlamydia trachomatis, PLoS ONE, vol.10, 2015. ,
Identification of a family of type III secreted effectors conserved in pathogenic Chlamydiae, Infect. Immun, vol.79, pp.571-580, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00568001
Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor, Proc. Natl. Acad. Sci. U.S.A, vol.109, pp.5621-5626, 2012. ,
Optimal description of a protein structure in terms of multiple groups undergoing TLS motion, Acta Crystallogr. D. Biol. Crystallogr, vol.62, pp.439-450, 2006. ,
Identification of novel type III secretion chaperone-substrate complexes of Chlamydia trachomatis, PLoS ONE, vol.8, p.56292, 2013. ,
A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneri, Mol. Microbiol, vol.56, pp.1627-1635, 2005. ,
The various and varying roles of specific chaperones in type III secretion systems, Curr. Opin. Microbiol, vol.6, pp.7-14, 2003. ,
Chlamydial protease-like activity factor and type III secreted effectors cooperate in inhibition of p65 nuclear translocation, vol.7, pp.1427-1443, 2016. ,
Rapid grid-based construction of the molecular surface and the use of induced surface charge to calculate reaction field energies: applications to the molecular systems and geometric objects, J. Comput. Chem, vol.23, pp.128-137, 2002. ,
Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms, Mol. Microbiol, vol.82, pp.1185-1203, 2011. ,
Cultivation and laboratory maintenance of Chlamydia trachomatis, Curr. Protoc. Microbiol. 11A, vol.1, 2005. ,
New surface contacts formed upon reductive lysine methylation: improving the probability of protein crystallization, Protein Sci, vol.19, pp.1395-1404, 2010. ,
The Chlamydia type III secretion system C-ring engages a chaperone-effector protein complex, PLoS Pathog, vol.5, p.1000579, 2009. ,
A directed screen for chlamydial proteins secreted by a type III mechanism identifies a translocated protein and numerous other new candidates, Mol. Microbiol, vol.56, pp.1636-1647, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00021366
Secretion of predicted Inc proteins of Chlamydia pneumoniae by a heterologous type III machinery, Mol. Microbiol, vol.39, pp.792-800, 2001. ,
, Trachoma. Lancet, vol.384, pp.2142-2152, 2014.
Expanded roles for multicargo and class 1B effector chaperones in type III secretion, J. Bacteriol, vol.194, pp.3767-3773, 2012. ,
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice, Nucleic Acids Res, vol.22, pp.4673-4680, 1994. ,
Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates, Genome Res, vol.18, pp.161-171, 2008. ,
New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition, Cell. Mol. Life Sci, vol.66, pp.3685-3695, 2009. ,
Quantitative monitoring of the Chlamydia trachomatis developmental cycle using GFP-expressing bacteria, microscopy and flow cytometry, PLoS ONE, vol.9, p.99197, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01448137
Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily, Proc. Natl. Acad. Sci. U.S.A, vol.110, 2013. ,
, , 2006.
, Lysine methylation as a routine rescue strategy for protein crystallization, Structure, vol.14, pp.1617-1622
Development of a transformation system for Chlamydia trachomatis: restoration of glycogen biosynthesis by acquisition of a plasmid shuttle vector, PLoS Pathog, vol.7, p.1002258, 2011. ,
Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes, Nat. Chem. Biol, vol.6, pp.534-540, 2010. ,
DOI : 10.1038/nchembio.386
LGA: a method for finding 3D similarities in protein structures, Nucleic Acids Res, vol.31, pp.3370-3374, 2003. ,
DOI : 10.1093/nar/gkg571
URL : https://academic.oup.com/nar/article-pdf/31/13/3370/9487387/gkg571.pdf
Identification of antigen-specific antibody responses associated with upper genital tract pathology in mice infected with Chlamydia muridarum, Infect. Immun, vol.80, pp.1098-1106, 2012. ,