Defects in trafficking bridge Parkinson's disease pathology and genetics, Nature, vol.111, issue.7628, pp.207-216, 2016. ,
DOI : 10.1073/pnas.1405752111
Wiring through tunneling nanotubes - from electrical signals to organelle transfer, Journal of Cell Science, vol.125, issue.5, pp.1089-1098, 2012. ,
DOI : 10.1242/jcs.083279
URL : https://hal.archives-ouvertes.fr/pasteur-00716392
,
, EMBO J, vol.35, pp.2120-2138
Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases, Prion, vol.528, issue.7580, pp.344-351, 2016. ,
DOI : 10.1182/blood-2015-03-634238
Cell Biology of Prions and Prionoids: A Status Report, Trends in Cell Biology, vol.26, issue.1, pp.40-51, 2016. ,
DOI : 10.1016/j.tcb.2015.08.007
Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission, Neurobiology of Disease, vol.42, issue.3, pp.360-367, 2011. ,
DOI : 10.1016/j.nbd.2011.01.029
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo, PLoS ONE, vol.389, issue.6, p.39465 ,
DOI : 10.1371/journal.pone.0039465.s004
Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-?? secretion via deregulated lysosomal exocytosis, Nature Communications, vol.365, issue.1, p.2734, 2013. ,
DOI : 10.1056/NEJMoa1108046
Prion strains are differentially released through the exosomal pathway, Cellular and Molecular Life Sciences, vol.6, issue.12, pp.1185-1196, 2015. ,
DOI : 10.1371/journal.ppat.1000859
URL : https://hal.archives-ouvertes.fr/hal-02132263
Transcellular spreading of huntingtin aggregates in the Drosophila brain, Proc. Natl. Acad. Sci. USA, pp.5427-5433, 2015. ,
Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and ??-synuclein aggregation, Experimental & Molecular Medicine, vol.23, issue.3, p.153, 2015. ,
DOI : 10.1093/hmg/ddu105
Axonal transport and secretion of fibrillar forms of ??-synuclein, A??42 peptide and HTTExon 1, Acta Neuropathologica, vol.288, issue.Suppl 3, pp.539-548, 2016. ,
DOI : 10.1074/jbc.M112.394528
Prion-like transmission of protein aggregates in neurodegenerative diseases, Nature Reviews Molecular Cell Biology, vol.4, issue.4, pp.301-307, 2010. ,
DOI : 10.1038/ncb1901
URL : https://hal.archives-ouvertes.fr/hal-01183206
Oxidative Stress and Lysosomes: CNS-Related Consequences and Implications for Lysosomal Enhancement Strategies and Induction of Autophagy, Antioxidants & Redox Signaling, vol.8, issue.1-2, pp.185-196, 2006. ,
DOI : 10.1089/ars.2006.8.185
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation, Cell Reports, vol.11, issue.8, pp.1176-1183, 2015. ,
DOI : 10.1016/j.celrep.2015.04.043
Constitutive secretion of tau protein by an unconventional mechanism, Neurobiology of Disease, vol.48, issue.3, pp.356-366, 2012. ,
DOI : 10.1016/j.nbd.2012.05.021
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid ? (A?) production in the trans-Golgi network, Proc. Natl. Acad. Sci. USA, pp.2077-2082, 2012. ,
Transmission and spreading of tauopathy in transgenic mouse brain, Nature Cell Biology, vol.8, issue.7, pp.909-913, 2009. ,
DOI : 10.1038/labinvest.3780257
Intercellular transfer of tau aggregates and spreading of tau pathology: Implications for therapeutic strategies, Neuropharmacology, vol.76, pp.9-15, 2014. ,
DOI : 10.1016/j.neuropharm.2013.08.037
Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage, Neurochemistry International, vol.62, issue.1, pp.1-7, 2013. ,
DOI : 10.1016/j.neuint.2012.10.010
URL : https://doi.org/10.1016/j.neuint.2012.10.010
Prion-infected cells regulate the release of exosomes with distinct ultrastructural features, The FASEB Journal, vol.263, issue.10, pp.4160-417311, 2012. ,
DOI : 10.1038/nature03989
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles, Annual Review of Cell and Developmental Biology, vol.30, issue.1, 2014. ,
DOI : 10.1146/annurev-cellbio-101512-122326
, Annu. Rev. Cell Dev. Biol, vol.30, pp.255-289
The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration, Biochemical Journal, vol.452, issue.1, pp.1-17, 2013. ,
DOI : 10.1042/BJ20121898
URL : https://hal.archives-ouvertes.fr/pasteur-00874678
Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes, Journal of Cell Science, vol.126, issue.16, pp.3678-3685, 2013. ,
DOI : 10.1242/jcs.126086
URL : https://hal.archives-ouvertes.fr/pasteur-00874692
Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death, Proc. Natl. Acad, 2004. ,
DOI : 10.1002/ana.410110406
, , pp.12271-12276
Endogenous prion protein conversion is required for prion-induced neuritic alterations and neuronal death, The FASEB Journal, vol.68, issue.9, pp.3854-386111, 2012. ,
DOI : 10.1016/j.molcel.2007.04.001
URL : https://hal.archives-ouvertes.fr/hal-01542871
Impaired Degradation of Mutant ??-Synuclein by Chaperone-Mediated Autophagy, Science, vol.305, issue.5688, pp.1292-1295, 2004. ,
DOI : 10.1126/science.1101738
Different Species of ??-Synuclein Oligomers Induce Calcium Influx and Seeding, Journal of Neuroscience, vol.27, issue.34, pp.9220-9232, 2007. ,
DOI : 10.1523/JNEUROSCI.2617-07.2007
Exosomal cell-to-cell transmission of alpha synuclein oligomers, Molecular Neurodegeneration, vol.7, issue.1, pp.421750-1326, 2012. ,
DOI : 10.1247/csf.23.33
Stabilization of ??-Synuclein Secondary Structure upon Binding to Synthetic Membranes, Journal of Biological Chemistry, vol.268, issue.16, pp.9443-9449, 1998. ,
DOI : 10.1021/bi00772a015
TFEB-mediated autophagy rescues midbrain dopamine neurons from ??-synuclein toxicity, Proc. Natl. Acad. Sci. USA, pp.1817-1826, 2013. ,
DOI : 10.1016/j.jneumeth.2011.06.012
Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes, Scientific Reports, vol.5, issue.1, p.39632, 2016. ,
DOI : 10.1016/j.stem.2009.08.017
URL : https://hal.archives-ouvertes.fr/pasteur-01511571
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of ??-synuclein, Proc. Natl. Acad. Sci. USA, pp.13010-13015, 2009. ,
DOI : 10.1074/jbc.M105326200
The Cellular Phase of Alzheimer???s Disease, Cell, vol.164, issue.4, pp.603-615, 2016. ,
DOI : 10.1016/j.cell.2015.12.056
Exposure to ALS-FTD-CSF generates TDP-43 aggregates in glioblastoma cells through exosomes and TNTslike structure, Oncotarget, vol.6, pp.24178-24191, 2015. ,
Lysosomal Membrane Damage in Soluble A??-Mediated Cell Death in Alzheimer's Disease, Neurobiology of Disease, vol.8, issue.1, pp.19-310364, 2000. ,
DOI : 10.1006/nbdi.2000.0364
Spreading of amyloid-?? peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance, Neurobiology of Disease, vol.65, pp.82-92, 2014. ,
DOI : 10.1016/j.nbd.2013.12.019
ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-?? accumulation, Journal of Cell Science, vol.64, issue.14, pp.2520-2528, 2015. ,
DOI : 10.1083/jcb.200505082
URL : http://jcs.biologists.org/content/joces/128/14/2520.full.pdf
Impact of lysosome status on extracellular vesicle content and release, Ageing Research Reviews, vol.32, pp.65-74, 2016. ,
DOI : 10.1016/j.arr.2016.05.001
URL : http://europepmc.org/articles/pmc5154730?pdf=render
Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking, Cellular Immunology, vol.254, issue.2, pp.142-148, 2009. ,
DOI : 10.1016/j.cellimm.2008.08.005
TDP-43 is intercellularly transmitted across axon terminals, The Journal of Cell Biology, vol.2, issue.4, pp.897-911, 2015. ,
DOI : 10.1093/hmg/ddu409
URL : http://jcb.rupress.org/content/jcb/211/4/897.full.pdf
Cells release prions in association with exosomes, Proc. Natl. Acad. Sci. USA, pp.9683-9688, 2004. ,
DOI : 10.1247/csf.27.443
URL : http://www.pnas.org/content/101/26/9683.full.pdf
Brain Disorders Due to Lysosomal Dysfunction, Annual Review of Neuroscience, vol.39, issue.1, pp.277-295, 2016. ,
DOI : 10.1146/annurev-neuro-070815-014031
2013. ?-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis, PLoS One, vol.8 ,
Neuron-to-neuron transmission of ??-synuclein fibrils through axonal transport, Annals of Neurology, vol.69, issue.4, pp.517-524, 2012. ,
DOI : 10.1002/cm.21019
URL : https://hal.archives-ouvertes.fr/hal-01183063
Propagation of Tau Misfolding from the Outside to the Inside of a Cell, Journal of Biological Chemistry, vol.9, issue.19, pp.12845-12852, 2009. ,
DOI : 10.1074/jbc.M805627200
Lysosomal membrane permeabilization causes oxidative stress and ferritin induction in macrophages, FEBS Letters, vol.27, issue.4, pp.623-629, 2011. ,
DOI : 10.3109/10715769709065788
URL : http://onlinelibrary.wiley.com/doi/10.1016/j.febslet.2010.12.043/pdf
The role of lipid???protein interactions in amyloid-type protein fibril formation, Chemistry and Physics of Lipids, vol.141, issue.1-2, pp.72-82, 2006. ,
DOI : 10.1016/j.chemphyslip.2006.02.006
Prions hijack tunnelling nanotubes for intercellular spread, Nature Cell Biology, vol.177, issue.3, pp.328-336, 2009. ,
DOI : 10.1038/nprot.2006.356
URL : https://hal.archives-ouvertes.fr/pasteur-00368712
Myo10 is a key regulator of TNT formation in neuronal cells, Journal of Cell Science, vol.126, issue.19, pp.4424-4435, 2013. ,
DOI : 10.1242/jcs.129239
URL : https://hal.archives-ouvertes.fr/pasteur-00874699
Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases, Nature Medicine, vol.62, issue.2, pp.130-138, 2014. ,
DOI : 10.1016/j.celrep.2013.06.007
Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression, European Journal of Neuroscience, vol.64, issue.5, pp.1119-1130, 2008. ,
DOI : 10.1073/pnas.83.11.4040
??-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells, Journal of Clinical Investigation, vol.121, issue.2, pp.715-725, 2011. ,
DOI : 10.1172/JCI43366DS1
URL : http://www.jci.org/articles/view/43366/files/pdf
Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders, Pharmacology & Therapeutics, vol.172, pp.22-33, 2017. ,
DOI : 10.1016/j.pharmthera.2016.11.010
Translation of the Prion Protein mRNA Is Robust in Astrocytes but Does Not Amplify during Reactive Astrocytosis in the Mouse Brain, PLoS ONE, vol.12, issue.4, p.95958, 2014. ,
DOI : 10.1371/journal.pone.0095958.g005
Nonclassical exocytosis of ?-synuclein is sensitive to folding states and promoted under stress conditions, J. Neurochem, vol.113, pp.1263-1274, 2010. ,
DOI : 10.1111/j.1471-4159.2010.06695.x
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2010.06695.x/pdf
Visualization of prion-like transfer in Huntington's disease models, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1863, issue.3, pp.793-800, 2017. ,
DOI : 10.1016/j.bbadis.2016.12.015
Transfer of Scrapie Prion Infectivity by Cell Contact in Culture, Current Biology, vol.12, issue.7, pp.523-530, 2002. ,
DOI : 10.1016/S0960-9822(02)00722-4
Trans-cellular Propagation of Tau Aggregation by Fibrillar Species, Journal of Biological Chemistry, vol.11, issue.23, 2012. ,
DOI : 10.1016/j.neuron.2005.05.010
The Role of Oxidative Stress in Neurodegenerative Diseases, Experimental Neurobiology, vol.24, issue.4, pp.325-340, 2015. ,
DOI : 10.5607/en.2015.24.4.325
Highly infectious CJD particles lack prion protein but contain many viral-linked peptides by LC-MS/MS, Journal of Cellular Biochemistry, vol.115, pp.2012-2021, 2014. ,
DOI : 10.1002/jcb.24873
Lewy body???like pathology in long-term embryonic nigral transplants in Parkinson's disease, Nature Medicine, vol.3, issue.5, pp.504-506, 2008. ,
DOI : 10.1038/nm1747
Clearance and deposition of extracellular ??-synuclein aggregates in microglia, Biochemical and Biophysical Research Communications, vol.372, issue.3, pp.423-428, 2008. ,
DOI : 10.1016/j.bbrc.2008.05.045
Direct Transfer of ??-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies, Journal of Biological Chemistry, vol.9, issue.12, pp.9262-9272, 2010. ,
DOI : 10.1074/jbc.M807482200
Autophagic failure promotes the exocytosis and intercellular transfer of ??-synuclein, Experimental & Molecular Medicine, vol.3, issue.5, p.22, 2013. ,
DOI : 10.1083/jcb.201003122
Amyloid-?? peptide induces oligodendrocyte death by activating the neutral sphingomyelinase???ceramide pathway, The Journal of Cell Biology, vol.21, issue.1, pp.123-131, 2004. ,
DOI : 10.1073/pnas.96.7.4089
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease, Movement Disorders, vol.24, issue.8, pp.1091-1096, 2010. ,
DOI : 10.1093/jnen/60.8.741
Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide, Molecular Neurodegeneration, vol.8, issue.1, pp.271750-1326, 2013. ,
DOI : 10.1083/jcb.201002100
The lysosome as a command-and-control center for cellular metabolism, The Journal of Cell Biology, vol.14, issue.6, pp.653-664, 2016. ,
DOI : 10.1038/nrm3025
Calcium Homeostasis and Mitochondrial Dysfunction in Striatal Neurons of Huntington Disease, Journal of Biological Chemistry, vol.64, issue.9, pp.5780-5789, 2008. ,
DOI : 10.1016/S0143-4160(03)00145-3
Trans-Synaptic Spread of Tau Pathology In Vivo, PLoS ONE, vol.25, issue.2, 2012. ,
DOI : 10.1371/journal.pone.0031302.g008
2017. ?-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading, Acta Neuropathol ,
Exogenous ??-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells, Proc. Natl. Acad. Sci. USA, pp.20051-20056, 2009. ,
DOI : 10.1038/ncb1901
Intracerebral inoculation of pathological ??-synuclein initiates a rapidly progressive neurodegenerative ??-synucleinopathy in mice, The Journal of Experimental Medicine, vol.52, issue.Suppl, pp.975-986, 2012. ,
DOI : 10.1074/jbc.274.28.19509
Pathological ??-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice, Science, vol.67, issue.5, pp.949-953, 2012. ,
DOI : 10.1097/NEN.0b013e3186fc995
Neurons and Astrocytes Respond to Prion Infection by Inducing Microglia Recruitment, Journal of Neuroscience, vol.24, issue.3, pp.620-627, 2004. ,
DOI : 10.1523/JNEUROSCI.4303-03.2004
URL : https://hal.archives-ouvertes.fr/hal-00091368
Identification of an Intracellular Site of Prion Conversion, PLoS Pathogens, vol.38, issue.4, 2009. ,
DOI : 10.1371/journal.ppat.1000426.s009
URL : https://hal.archives-ouvertes.fr/pasteur-00396879
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB, Autophagy, vol.325, issue.6, pp.903-914, 2012. ,
DOI : 10.1074/jbc.M107694200
The Autophagy???Lysosomal Pathway in Neurodegeneration: A TFEB Perspective, Trends in Neurosciences, vol.39, issue.4, pp.221-234, 2016. ,
DOI : 10.1016/j.tins.2016.02.002
URL : http://europepmc.org/articles/pmc4928589?pdf=render
Exosomes: Mechanisms of Uptake, Journal of Circulating Biomarkers, vol.66, p.61186, 2015. ,
DOI : 10.1155/2012/971907
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB, Nature Cell Biology, vol.2011, issue.3, pp.288-299, 2015. ,
DOI : 10.1093/nar/30.1.207
URL : http://europepmc.org/articles/pmc4801004?pdf=render
Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system, Nature Communications, vol.2, issue.1, p.2250, 2013. ,
DOI : 10.1371/journal.pone.0001118
URL : http://www.nature.com/articles/ncomms3250.pdf
Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice, Science Translational Medicine, vol.6, issue.4, pp.206-138, 2013. ,
DOI : 10.1371/journal.pone.0019339
The role of the cofilin-actin rod stress response in neurodegenerative diseases uncovers potential new drug targets, BioArchitecture, vol.28, issue.6, pp.204-208, 2012. ,
DOI : 10.1128/MCB.00079-08
Brief Reports: Lysosomal Cross-Correction by Hematopoietic Stem Cell-Derived Macrophages Via Tunneling Nanotubes, STEM CELLS, vol.25, issue.1, pp.301-309, 2015. ,
DOI : 10.1681/ASN.2013060598
URL : http://onlinelibrary.wiley.com/doi/10.1002/stem.1835/pdf
Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of ??-Amyloid, Journal of Neuroscience, vol.32, issue.26, pp.8767-8777, 2012. ,
DOI : 10.1523/JNEUROSCI.0615-12.2012
Presenilin-1, Nicastrin, Amyloid Precursor Protein, and ??-Secretase Activity Are Co-localized in the Lysosomal Membrane, Journal of Biological Chemistry, vol.64, issue.29, pp.26687-26694, 2003. ,
DOI : 10.1073/pnas.87.10.3861
URL : http://www.jbc.org/content/278/29/26687.full.pdf
Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain, Nature Communications, vol.6, issue.1, p.6768, 2015. ,
DOI : 10.1186/1471-2105-9-346
Transneuronal propagation of mutant huntingtin contributes to non???cell autonomous pathology in neurons, Nature Neuroscience, vol.19, issue.8, pp.1064-1072, 2014. ,
DOI : 10.1126/science.1227157
Early etiology of Alzheimer???s disease: tipping the balance toward autophagy or endosomal dysfunction?, Acta Neuropathologica, vol.107, issue.20, pp.363-381, 2015. ,
DOI : 10.1073/pnas.0914725107
URL : https://link.springer.com/content/pdf/10.1007%2Fs00401-014-1379-7.pdf
Fibrillar ??-Synuclein and Huntingtin Exon 1 Assemblies Are Toxic to the Cells, Biophysical Journal, vol.102, issue.12, pp.2894-2905, 2012. ,
DOI : 10.1016/j.bpj.2012.04.050
URL : https://hal.archives-ouvertes.fr/hal-01183141
TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion, Scientific Reports, vol.32, issue.1, p.22155, 2016. ,
DOI : 10.1523/JNEUROSCI.5053-11.2012
URL : http://www.nature.com/articles/srep22155.pdf
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB, EMBO Molecular Medicine, vol.6, issue.9, pp.1142-1160, 2014. ,
DOI : 10.15252/emmm.201303671
URL : http://embomolmed.embopress.org/content/embomm/6/9/1142.full.pdf
Prion-like spread of protein aggregates in neurodegeneration: Figure 1., The Journal of Experimental Medicine, vol.20, issue.5, pp.889-893, 2012. ,
DOI : 10.1002/ana.10795
URL : http://jem.rupress.org/content/jem/209/5/889.full.pdf
Physiological release of endogenous tau is stimulated by neuronal activity, EMBO reports, vol.309, issue.4, pp.389-394, 2013. ,
DOI : 10.1016/j.nbd.2011.01.029
URL : http://embor.embopress.org/content/embor/14/4/389.full.pdf
Intrinsic Resistance of Oligodendrocytes to Prion Infection, Journal of Neuroscience, vol.24, issue.26, pp.5974-5981, 2004. ,
DOI : 10.1523/JNEUROSCI.0122-04.2004
URL : http://www.jneurosci.org/content/jneuro/24/26/5974.full.pdf
Novel proteinaceous infectious particles cause scrapie, Science, vol.216, issue.4542, pp.136-144, 1982. ,
DOI : 10.1126/science.6801762
Biology and Genetics of Prions Causing Neurodegeneration, Annual Review of Genetics, vol.47, issue.1, 2013. ,
DOI : 10.1146/annurev-genet-110711-155524
URL : http://europepmc.org/articles/pmc4010318?pdf=render
, Annu. Rev. Genet, vol.47, pp.601-623
Structural variation in amyloid-?? fibrils from Alzheimer's disease clinical subtypes, Nature, vol.82, issue.7636, pp.217-221, 2017. ,
DOI : 10.1016/j.neuron.2014.04.047
The role of extracellular vesicles in neurodegenerative diseases, Biochemical and Biophysical Research Communications, vol.483, issue.4, pp.1178-1186, 2017. ,
DOI : 10.1016/j.bbrc.2016.09.090
Alzheimer's disease beta-amyloid peptides are released in association with exosomes, Proc. Natl. Acad. Sci. USA, pp.11172-11177, 2006. ,
DOI : 10.1136/jcp.35.10.1092
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates, Nature Cell Biology, vol.309, issue.2, pp.219-225, 2009. ,
DOI : 10.1016/S0092-8674(00)80514-0
URL : https://hal.archives-ouvertes.fr/hal-01183798
Alpha-synuclein transfers from neurons to oligodendrocytes, Glia, vol.22, issue.Pt 1, pp.387-398 ,
DOI : 10.1111/j.1750-3639.2011.00530.x
URL : https://hal.archives-ouvertes.fr/hal-01181201
The activities of amyloids from a structural perspective, Nature, vol.43, issue.7628, pp.227-235, 2016. ,
DOI : 10.1021/bi049621l
Lysosomal pathology associated with ?-synuclein accumulation in transgenic models using an eGFP fusion protein, Journal of Neuroscience Research, vol.866, issue.2, pp.247-259, 2005. ,
DOI : 10.1016/S0002-9440(10)64553-1
The missing link: does tunnelling nanotube-based supercellularity provide a new understanding of chronic and lifestyle diseases?, Open Biology, vol.1807, issue.6, p.160057, 2016. ,
DOI : 10.1038/ncomms7238
Nanotubular Highways for Intercellular Organelle Transport, Science, vol.303, issue.5660, pp.1007-1010, 2004. ,
DOI : 10.1126/science.1093133
Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease, Journal of Biological Chemistry, vol.11, issue.6, pp.3842-3849, 2012. ,
DOI : 10.1523/JNEUROSCI.0800-08.2008
Prion propagation and toxicity in vivo occur in two distinct mechanistic phases, Nature, vol.21, issue.7335, pp.540-542, 2011. ,
DOI : 10.1093/emboj/cdf653
Prions and Protein Assemblies that Convey Biological Information in Health and Disease, Neuron, vol.89, issue.3, pp.433-448, 2016. ,
DOI : 10.1016/j.neuron.2016.01.026
Restricted Location of PSEN2/??-Secretase Determines Substrate Specificity and Generates an Intracellular A?? Pool, Cell, vol.166, issue.1, pp.193-208, 2016. ,
DOI : 10.1016/j.cell.2016.05.020
A Gene Network Regulating Lysosomal Biogenesis and Function, Science, vol.269, issue.5939, pp.473-477, 2009. ,
DOI : 10.1042/BJ20090567
Mechanochemical Signaling Directs Cell-Shape Change, Biophysical Journal, vol.112, issue.2, pp.207-214, 2017. ,
DOI : 10.1016/j.bpj.2016.12.015
The retromer complex - endosomal protein recycling and beyond, Journal of Cell Science, vol.125, issue.20, pp.4693-4702, 2012. ,
DOI : 10.1242/jcs.103440
TFEB Links Autophagy to Lysosomal Biogenesis, Science, vol.15, issue.16, pp.1429-1433, 2011. ,
DOI : 10.1097/00001756-200411150-00001
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB, The EMBO Journal, vol.12, issue.5, pp.1095-1108, 2012. ,
DOI : 10.1038/nrm3025
Signals from the lysosome: a control centre for cellular clearance and energy metabolism, Nature Reviews Molecular Cell Biology, vol.13, issue.5, 2013. ,
DOI : 10.1016/S0960-9822(03)00506-2
URL : http://europepmc.org/articles/pmc4387238?pdf=render
, Nat. Rev. Mol. Cell Biol, vol.14, pp.283-296
Axonal and Transynaptic Spread of Prions, Journal of Virology, vol.88, issue.15, pp.8640-865500378, 2014. ,
DOI : 10.1128/JVI.00378-14
Dysregulation of Calcium Homeostasis in Alzheimer???s Disease, Neurochemical Research, vol.93, issue.10, pp.1824-1829, 2009. ,
DOI : 10.1016/j.molmed.2007.12.006
Retromer in Alzheimer disease, Parkinson disease and other neurological disorders, Nature Reviews Neuroscience, vol.482, issue.3, pp.126-132, 2015. ,
DOI : 10.1073/pnas.1413111111
Accumulation of amyloid-?? by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons, Molecular Neurodegeneration, vol.58, issue.1, 2016. ,
DOI : 10.1002/ana.20524
??-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies, Proc. Natl. Acad. Sci. USA, pp.386469-6473, 1998. ,
DOI : 10.1016/0896-6273(89)90210-9
Prion Protein and Its Conformational Conversion: A Structural Perspective, Top. Curr. Chem, vol.305, pp.135-167, 2011. ,
DOI : 10.1007/128_2011_165
PGC-1? rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function, Sci. Transl. Med, vol.4, pp.142-97, 2012. ,
Sorting out release, uptake and processing of alpha-synuclein during prion-like spread of pathology, Journal of Neurochemistry, vol.89, issue.1, pp.275-289, 2016. ,
DOI : 10.1016/j.ajhg.2011.06.008
Toxic species in amyloid disorders: Oligomers or mature fibrils, Ann. Indian Acad. Neurol, vol.18, pp.138-145, 2015. ,
Trafficking and degradation pathways in pathogenic conversion of prions and prion-like proteins in neurodegenerative diseases, Virus Research, vol.207, pp.146-154, 2015. ,
DOI : 10.1016/j.virusres.2015.01.019
Astrocyteto-neuron intercellular prion transfer is mediated by cell-cell contact. Sci. Rep. 6:20762. http ://dx Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies, J. Biol. Chem, vol.282, pp.18197-18205, 2007. ,
Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells, Cell Death & Differentiation, vol.33, issue.7, pp.1181-1191, 2015. ,
DOI : 10.1369/jhc.2009.954701
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing, Human Molecular Genetics, vol.93, issue.Pt 2, pp.4153-4170, 2009. ,
DOI : 10.1083/jcb.93.1.144
Tunneling-nanotube development in astrocytes depends on p53 activation, Cell Death & Differentiation, vol.23, issue.4, pp.732-742, 2011. ,
DOI : 10.1111/j.1432-1033.1991.tb16305.x
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity, The EMBO Journal, vol.34, issue.24, pp.3028-3041, 2015. ,
DOI : 10.15252/embj.201592748
VPS35 haploinsufficiency increases Alzheimer???s disease neuropathology, The Journal of Cell Biology, vol.21, issue.5, pp.765-779, 2011. ,
DOI : 10.1016/j.ajhg.2011.06.008
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons, Journal of Biological Chemistry, vol.150, issue.3, pp.1856-1870, 2013. ,
DOI : 10.1016/S0962-8924(00)01852-3
URL : https://hal.archives-ouvertes.fr/pasteur-00874385
Neuronal activity enhances tau propagation and tau pathology in vivo, Nature Neuroscience, vol.24, issue.8, pp.1085-1092, 2016. ,
DOI : 10.1016/j.neurobiolaging.2012.05.010
Adult mouse astrocytes degrade amyloid-?? in vitro and in situ, Nature Medicine, vol.20, issue.4, pp.453-457, 2003. ,
DOI : 10.1038/87945
Enhancing Astrocytic Lysosome Biogenesis Facilitates A?? Clearance and Attenuates Amyloid Plaque Pathogenesis, Journal of Neuroscience, vol.34, issue.29, pp.9607-9620, 2014. ,
DOI : 10.1523/JNEUROSCI.3788-13.2014
URL : http://www.jneurosci.org/content/jneuro/34/29/9607.full.pdf
Mutation in VPS35 associated with Parkinson???s disease impairs WASH complex association and inhibits autophagy, Nature Communications, vol.122, issue.1, p.3828, 2014. ,
DOI : 10.1242/jcs.048686
URL : http://www.nature.com/articles/ncomms4828.pdf
A neuroprotective role for microglia in prion diseases, The Journal of Experimental Medicine, vol.15, issue.6, pp.1047-1059, 2016. ,
DOI : 10.1038/nn.3641
URL : http://europepmc.org/articles/pmc4886355?pdf=render
Prion aggregates transfer through tunneling nanotubes in endocytic vesicles, Prion, vol.7, issue.2, pp.125-135, 2015. ,
DOI : 10.1038/nmeth.2075
URL : http://www.tandfonline.com/doi/pdf/10.1080/19336896.2015.1025189?needAccess=true
A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease, The American Journal of Human Genetics, vol.89, issue.1, pp.168-175, 2011. ,
DOI : 10.1016/j.ajhg.2011.06.008