Botulinum Toxin as a Biological Weapon, JAMA, vol.285, issue.8, pp.1059-1070, 2001. ,
DOI : 10.1001/jama.285.8.1059
Clostridium botulinum type F with recent observations on other types Botulinum neurotoxins as biothreat agents, J. Infect. Dis. J. Bioterr. Biodef, vol.109, pp.107-128, 1961. ,
DOI : 10.1093/infdis/109.2.107
Montecucco, C. botulinum neurotoxins: Genetic, structural and mechanistic insights [CrossRef] [PubMed] 6. Fischer, A.; Montal, M. Molecular dissection of botulinum neurotoxin reveals interdomain chaperone function How do the botulinum toxins block neurotransmitter release: From botulism to the molecular mechanism of action [CrossRef] 8. Pantano, S.; Montecucco, C. The blockade of the neurotransmitter release apparatus by botulinum neurotoxins, CrossRef] [PubMed] 9. Binz, T. Clostridial neurotoxin light chains: Devices for snare cleavage mediated blockade of neurotransmission, pp.9-24, 2008. ,
N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A, Nature Structural & Molecular Biology, vol.364, issue.7, pp.656-662, 2016. ,
DOI : 10.1002/(SICI)1099-1352(199909/10)12:5<279::AID-JMR473>3.0.CO;2-3
The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves, FEBS Letters, vol.279, issue.8, pp.2011-2014, 2006. ,
DOI : 10.1074/jbc.M407502200
SV2 Is the Protein Receptor for Botulinum Neurotoxin A, Science, vol.312, issue.5773, pp.592-596, 2006. ,
DOI : 10.1126/science.1123654
Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells, The Journal of Cell Biology, vol.263, issue.7, pp.1293-1303, 2003. ,
DOI : 10.1016/S0896-6273(02)00671-2
URL : http://jcb.rupress.org/content/jcb/162/7/1293.full.pdf
Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons, The Journal of Cell Biology, vol.80, issue.7, pp.1511-1522, 2007. ,
DOI : 10.1021/bi0494673
URL : http://jcb.rupress.org/content/jcb/179/7/1511.full.pdf
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites, Molecular Microbiology, vol.355, issue.1, pp.143-156, 2011. ,
DOI : 10.1007/PL00004951
Botulinum Neurotoxin D Uses Synaptic Vesicle Protein SV2 and Gangliosides as Receptors, PLoS Pathogens, vol.276, issue.3, 2011. ,
DOI : 10.1371/journal.ppat.1002008.s003
URL : https://doi.org/10.1371/journal.ppat.1002008
Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins, Journal of Cell Science, vol.125, issue.13, pp.3233-3242, 2012. ,
DOI : 10.1242/jcs.103564
URL : http://jcs.biologists.org/content/joces/125/13/3233.full.pdf
Glycosylated SV2A and SV2B Mediate the Entry of Botulinum Neurotoxin E into Neurons, Molecular Biology of the Cell, vol.18, issue.12, pp.5226-5237, 2008. ,
DOI : 10.1523/JNEUROSCI.18-18-07200.1998
URL : http://www.molbiolcell.org/content/19/12/5226.full.pdf
Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type??E, Biochemical Journal, vol.58, issue.1, pp.37-47, 2013. ,
DOI : 10.1111/j.1462-5822.2011.01654.x
Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F, Biochemistry, vol.48, issue.24, pp.5631-5641, 2009. ,
DOI : 10.1021/bi9002138
URL : http://europepmc.org/articles/pmc2709598?pdf=render
Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor, Journal of Neurochemistry, vol.21, issue.6, pp.1942-1954, 2009. ,
DOI : 10.1042/bj2680123
Synaptotagmins I and II Act as Nerve Cell Receptors for Botulinum Neurotoxin G, Journal of Biological Chemistry, vol.12, issue.29, pp.30865-30870, 2004. ,
DOI : 10.1091/mbc.12.10.2947
URL : http://www.jbc.org/content/279/29/30865.full.pdf
,
Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5, FEBS Lett, vol.2012, issue.586, pp.109-115 ,
Beitraege zur kenntnis des toxins und antitoxins des Bacillus botulinus, Z. Hyg. Infekt, vol.76, pp.55-84, 1910. ,
Notes on Bacillus botulinus, J. Bacteriol, vol.4, pp.555-570, 1919. ,
The occurrence of Clostridium botulinum and Clostridium tetani in the soil of the United States, Health Lab. Sci, vol.15, pp.74-80, 1978. ,
The distribution of the spores of B. botulinus in the United States. IV, Journal of Infectious Diseases, vol.31, issue.6, pp.559-594, 1922. ,
DOI : 10.1093/infdis/31.6.559
Molecular Characterization of a Novel Botulinum Neurotoxin Type H Gene, The Journal of Infectious Diseases, vol.235, issue.2, pp.192-202, 2014. ,
DOI : 10.1111/j.1574-6968.2004.tb09561.x
A Novel Strain of Clostridium botulinum That Produces Type B and Type H Botulinum Toxins, The Journal of Infectious Diseases, vol.285, issue.2, pp.183-191 ,
DOI : 10.1001/jama.285.8.1059
A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin, Journal of Infectious Diseases, vol.32, issue.3, pp.379-385, 2016. ,
DOI : 10.1093/infdis/150.3.407
Purification and characterization of botulinum neurotoxin FA from a genetically modified Clostridium botulinum strain ,
Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H, Journal of Infectious Diseases, vol.2, issue.10, pp.1606-1614, 2016. ,
DOI : 10.1086/597310
Functional Characterization of Botulinum Neurotoxin Serotype H as a Hybrid of Known Serotypes F and A (BoNT F/A), Analytical Chemistry, vol.87, issue.7 ,
DOI : 10.1021/ac504716v
, Anal. Chem. 2015, vol.87, pp.3911-3917
Toxico-immunologic and serologic relationship of B. botulinus, type C, and B. parabotulinus, "seddon." XXII., Journal of Infectious Diseases, vol.35, issue.4, pp.347-352, 1924. ,
DOI : 10.1093/infdis/35.4.347
Mosaic structures of neurotoxins produced from Clostridium botulinum types C and D organisms, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1307, issue.2, pp.123-126, 1996. ,
DOI : 10.1016/0167-4781(96)00006-1
Antigenic variations in F type botulinum toxins. Attempted definitions by serological typing and classification of Clostridium botulinum, Medicina (B. Aires), vol.32, pp.596-606, 1972. ,
Seological classification and typing of Clostridium botulinum, Dev. Biol. Stand, vol.32, pp.175-183, 1976. ,
Differences in immunological responses of polyclonal botulinum A1 and A2 antitoxin against A1 and A2 toxin, Toxicon, vol.73, pp.9-16, 2013. ,
DOI : 10.1016/j.toxicon.2013.06.020
ABSTRACT, Applied and Environmental Microbiology, vol.78, issue.9, pp.3108-3113 ,
DOI : 10.1128/AEM.07967-11
Studies on strain 84 of Clostridium botulinum, Z. Bakteriol. Orig, vol.215, pp.212-220, 1970. ,
Serological subtrypes of botulinal neurotoxins In Botulinum and Tetanus Neurotoxins: Neurotransmission and Biomedical Aspects, pp.421-432, 1993. ,
Evidence that Plasmid-Borne Botulinum Neurotoxin Type B Genes Are Widespread among Clostridium botulinum Serotype B Strains, PLoS ONE, vol.104, issue.3, 2009. ,
DOI : 10.1371/journal.pone.0004829.t004
URL : https://doi.org/10.1371/journal.pone.0004829
Clostridium botulinum in the post-genomic era. Food Microbiol, pp.183-191, 2011. ,
DOI : 10.1016/j.fm.2010.03.005
Characterization of Clostridium botulinum type B neurotoxin associated with infant botulism in Japan, Infect. Immun, vol.66, pp.4811-4816, 1998. ,
Sequence Variation within Botulinum Neurotoxin Serotypes Impacts Antibody Binding and Neutralization, Infection and Immunity, vol.73, issue.9, pp.5450-5457, 2005. ,
DOI : 10.1128/IAI.73.9.5450-5457.2005
URL : http://iai.asm.org/content/73/9/5450.full.pdf
A Structural Perspective of the Sequence Variability Within Botulinum Neurotoxin Subtypes A1-A4, Journal of Molecular Biology, vol.362, issue.4, pp.733-742, 2006. ,
DOI : 10.1016/j.jmb.2006.07.040
Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes, Genome Research, vol.17, issue.7, pp.1082-1092, 2007. ,
DOI : 10.1101/gr.6282807
Genetic diversity within the botulinum neurotoxin-producing bacteria and their neurotoxins, Toxicon, vol.107, pp.2-8, 2015. ,
DOI : 10.1016/j.toxicon.2015.09.011
URL : https://manuscript.elsevier.com/S0041010115300702/pdf/S0041010115300702.pdf
Comparative genomic analyses reveal broad diversity in botulinum-toxin-producing Clostridia, BMC Genomics, vol.240, issue.17, p.17, 2016. ,
DOI : 10.1016/j.mimet.2014.11.011
URL : https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/s12864-016-2502-z?site=bmcgenomics.biomedcentral.com
The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins, J. Biol. Chem, vol.265, pp.9153-9158, 1990. ,
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene, European Journal of Biochemistry, vol.259, issue.1, pp.73-81, 1990. ,
DOI : 10.1016/0022-2836(86)90409-2
Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence, Appl. Environ. Microbiol, vol.58, pp.2345-2354, 1992. ,
C1 neurotoxin, Nucleic Acids Research, vol.18, issue.16, p.4924, 1990. ,
DOI : 10.1093/nar/18.16.4924
neurotoxin type D, Nucleic Acids Research, vol.18, issue.18, p.5556, 1990. ,
DOI : 10.1093/nar/18.18.5556
The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene, European Journal of Biochemistry, vol.157, issue.2, pp.657-667, 1992. ,
DOI : 10.1016/0378-1119(88)90330-7
Sequence of the gene encoding type F neurotoxin of Clostridium botulinum, FEMS Microbiol. Lett, vol.75, pp.225-230, 1992. ,
Nucleotide sequence of the gene coding for Clostridium botulinum (Clostridium argentinense) type G neurotoxin: Genealogical comparison with other clostridial neurotoxins, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1216, issue.3, pp.487-491, 1993. ,
DOI : 10.1016/0167-4781(93)90020-E
Sequences of the botulinal neurotoxin E derived from Clostridium botulinum type E (strain beluga) and Clostridium butyricum (strains ATCC 43181 and ATCC 43755), Biochemical and Biophysical Research Communications, vol.183, issue.1, pp.107-113, 1992. ,
DOI : 10.1016/0006-291X(92)91615-W
Sequence of the gene coding for the neurotoxin of Clostridium botulinum type A associated with infant botulism: comparison with other clostridial neurotoxins, Research in Microbiology, vol.144, issue.7, pp.547-556, 1993. ,
DOI : 10.1016/0923-2508(93)90004-L
Type A Containing Silent Type B Neurotoxin Gene Sequences, Journal of Biological Chemistry, vol.215, issue.18, pp.10786-10792, 1996. ,
DOI : 10.1007/BF01575751
Nucleotide sequence of the gene coding for non-proteolyticClostridium botulinum type B neurotoxin: Comparison with other clostridial neurotoxins, Current Microbiology, vol.204, issue.2, pp.101-110, 1994. ,
DOI : 10.1007/BF01569055
Characterization of the Genes Encoding the Botulinum Neurotoxin Complex in a Strain of Clostridium botulinum Producing Type B and F Neurotoxins, Current Microbiology, vol.37, issue.5, pp.312-318, 1998. ,
DOI : 10.1007/s002849900384
Analysis of the Botulinum Neurotoxin Type F Gene Clusters in Proteolytic and Nonproteolytic Clostridium botulinum and Clostridium barati, Current Microbiology, vol.37, issue.4, pp.262-268, 1998. ,
DOI : 10.1007/s002849900376
Detection of type A, B, and E botulism neurotoxin genes in Clostridium botulinum and other Clostridium species by PCR: Evidence of unexpressed type B toxin genes in type A toxigenic organisms, J. Clin. Microbiol, vol.32, pp.1911-1917, 1994. ,
Genetic Diversity Within Clostridium botulinum Serotypes, Botulinum Neurotoxin Gene Clusters and Toxin Subtypes, Curr. Top. Microbiol. Immunol, vol.364, pp.1-20, 2013. ,
DOI : 10.1007/978-3-662-45790-0_1
,
, Appl. Environ. Microbiol, vol.50, pp.63-67, 1985.
USE OF MONOCLONAL ANTIBODIES IN ENZYME LINKED IMMUNOSORBENT ASSAY (ELISA) FOR DETECTION OF BOTULINUM TYPE B TOXINS, Japanese Journal of Medical Science and Biology, vol.37, issue.3, pp.137-140, 1984. ,
DOI : 10.7883/yoken1952.37.137
Four different monoclonal antibodies against type C1 toxin of Clostridium botulinum, Infect. Immun, vol.38, pp.14-20, 1982. ,
The use of monoclonal antibodies to analyze the structure of Clostridium botulinum type E derivative toxin, Infect. Immun, vol.52, pp.786-791, 1986. ,
toxin produced in pure culture and an inoculated model cured meat system, Journal of Applied Bacteriology, vol.50, issue.4, pp.285-291, 1988. ,
DOI : 10.7883/yoken1952.37.137
Type A Associated with Infant Botulism in Japan, Microbiology and Immunology, vol.144, issue.10, pp.767-774, 1995. ,
DOI : 10.1016/0923-2508(93)90004-L
Genetic Diversity among Botulinum Neurotoxin-Producing Clostridial Strains, Journal of Bacteriology, vol.189, issue.3, pp.818-832, 2007. ,
DOI : 10.1128/JB.01180-06
Genetic Characterization of Clostridium botulinum Associated with Type B Infant Botulism in Japan, Journal of Clinical Microbiology, vol.47, issue.9, pp.2720-2728, 2009. ,
DOI : 10.1128/JCM.00077-09
Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum, BMC Genomics, vol.10, issue.1, p.10, 2009. ,
DOI : 10.1186/1471-2164-10-115
Biology and Genomic Analysis of Clostridium botulinum, Adv. Microb. Physiol, vol.55, pp.183-265, 2009. ,
DOI : 10.1016/S0065-2911(09)05503-9
Sequence Diversity of Genes Encoding Botulinum Neurotoxin Type F, Applied and Environmental Microbiology, vol.76, issue.14, pp.4805-4812, 2010. ,
DOI : 10.1128/AEM.03109-09
, A. Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222
, Appl. Environ. Microbiol, vol.77, pp.4217-4222, 2011.
Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype, BMC Microbiology, vol.12, issue.1, p.12, 2012. ,
DOI : 10.1186/1471-2164-9-75
Molecular characterization of Clostridium botulinum isolates from foodborne outbreaks in Thailand, PLoS ONE, vol.2014, issue.9, 2010. ,
DOI : 10.1371/journal.pone.0077792
URL : https://doi.org/10.1371/journal.pone.0077792
,
Two novel toxin variants revealed by whole-genome sequencing of 175 ,
, Clostridium botulinum type E strains, Appl. Environ. Microbiol, vol.80, pp.6334-6345, 2014.
Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype, PLoS ONE, p.10, 2015. ,
An Atypical Outbreak of Food-Borne Botulism Due to Clostridium botulinum Types B and E from Ham, Journal of Clinical Microbiology, vol.53, issue.2, pp.722-726, 2015. ,
DOI : 10.1128/JCM.02942-14
URL : https://hal.archives-ouvertes.fr/pasteur-01768473
,
Genomic characterization of Italian Clostridium botulinum group I strains, Infect. Genet. Evol, vol.36, pp.62-71, 2015. ,
Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1, FEBS Letters, vol.15, issue.1, pp.199-206, 2011. ,
DOI : 10.2174/138161209789271843
ABSTRACT, Infection and Immunity, vol.81, issue.10, pp.3894-3902, 2013. ,
DOI : 10.1128/IAI.00536-13
, Holotoxin activity of botulinum neurotoxin subtype A4 originating from a nontoxigenic Clostridium botulinum expression system
, Appl. Environ. Microbiol, vol.80, pp.7415-7422, 2014.
A.; Pellett, S. Persistence of botulinum neurotoxin A subtypes 1?5 in primary rat spinal cord cells, PLoS ONE, vol.2014, issue.9 ,
In??vivo onset and duration of action varies for botulinum neurotoxin A subtypes 1-5, Toxicon, vol.107, pp.37-42, 2015. ,
DOI : 10.1016/j.toxicon.2015.06.021
ABSTRACT, Applied and Environmental Microbiology, vol.77, issue.24, pp.8625-8634, 2011. ,
DOI : 10.1128/AEM.05155-11
Sequencing the Botulinum Neurotoxin Gene and Related Genes in Clostridium botulinum Type E Strains Reveals orfx3 and a Novel Type E Neurotoxin Subtype, Journal of Bacteriology, vol.189, issue.23, pp.8643-8650, 2007. ,
DOI : 10.1128/JB.00784-07
Botulinum neurotoxin homologs in non-clostridium species, FEBS Lett, vol.2015, issue.589, pp.342-348 ,
The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain, Scientific Reports, vol.9, issue.1 ,
DOI : 10.1371/journal.ppat.1003690
Bacteriology and pathology of neurotoxigenic clostridia In Botulinum and Tetanus Neurotoxins: Neurotransmission and Biomedical Aspects, pp.491-503, 1993. ,
Genomes, neurotoxins and biology of Clostridium botulinum Group I and Group II, Research in Microbiology, vol.166, issue.4, pp.303-317, 2015. ,
DOI : 10.1016/j.resmic.2014.10.010
Genomic sequences of six botulinum neurotoxin-producing strains representing three clostridial species illustrate the mobility and diversity of botulinum neurotoxin genes, Infection, Genetics and Evolution, vol.30, pp.102-113, 2015. ,
DOI : 10.1016/j.meegid.2014.12.002
Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements, BMC Genomics, vol.4, issue.1, 2011. ,
DOI : 10.1093/nar/gkm360
Identification of Clostridium Species and DNA Fingerprinting of Clostridium perfringens by Amplified Fragment Length Polymorphism Analysis, Journal of Clinical Microbiology, vol.44, issue.11 ,
DOI : 10.1128/JCM.01275-06
, J. Clin. Microbiol, vol.44, pp.4057-4065, 2006.
Genetic confirmation of identities of neurotoxigenic Clostridium baratii and Clostridium butyricum implicated as agents of infant botulism, J. Clin. Microbiol, vol.26, pp.2191-2192, 1988. ,
The Type F6 Neurotoxin Gene Cluster Locus of Group II Clostridium botulinum Has Evolved by Successive Disruption of Two Different Ancestral Precursors, Genome Biology and Evolution, vol.54, issue.5 ,
DOI : 10.1139/g11-019
, Genome Biol. Evol, vol.5, pp.1032-1037, 2013.
Identification of Clostridium botulinum with API 20 A, Rapid ID 32 A and RapID ANA II, FEMS Immunology and Medical Microbiology, vol.24, issue.3, pp.267-274, 1999. ,
DOI : 10.1016/S0928-8244(99)00041-3
Plasmid encoded neurotoxin genes in Clostridium botulinum serotype A subtypes, Biochemical and Biophysical Research Communications, vol.361, issue.1, pp.49-54, 2007. ,
DOI : 10.1016/j.bbrc.2007.06.166
, J.D
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids, PLoS ONE, vol.2, 2007. ,
Genomic and physiological variability within Group II (non-proteolytic) Clostridium botulinum, BMC Genomics, vol.14, issue.1, pp.14-333, 2013. ,
DOI : 10.1007/s00216-012-5767-3
Type E Neurotoxin Gene Clusters: Evidence Provided by Their Rare Plasmid-Borne Counterparts, Genome Biology and Evolution, vol.63, issue.3, pp.540-555, 2016. ,
DOI : 10.1128/AEM.00080-13
Characterization of the Neurotoxin Produced by Isolates Associated with Avian Botulism, Avian Diseases, vol.49, issue.3, pp.376-381, 2005. ,
DOI : 10.1637/7347-022305R1.1
Isolation of Clostridium botulinum Type G and Identification of Type G Botulinal Toxin in Humans: Report of Five Sudden Unexpected Deaths, Journal of Infectious Diseases, vol.143, issue.1, pp.22-27, 1981. ,
DOI : 10.1093/infdis/143.1.22
ABSTRACT, Applied and Environmental Microbiology, vol.81, issue.16, pp.5420-5429, 2015. ,
DOI : 10.1128/AEM.01159-15
Draft Genome Sequence of Clostridium botulinum B2 450 Strain from Wound Botulism in a Drug User in Italy, Genome Announcements, vol.3, issue.2 ,
DOI : 10.1371/journal.pone.0001271
A new anaerobic bacillus and its relation to botulism (originally published as Ueber einen neuen anaeroben Bacillus und seine Beziehungen zum Botulismus, Zeitschrift für Hygiene und Infektionskrankheiten, pp.1-56, 1897. ,
Ueber die Ursache der Darmstadter Bohnenvergiftung, Hyg. Rundsch, vol.14, pp.449-452, 1904. ,
Role of a protease in natural activation of Clostridium botulinum neurotoxin, Infect. Immun, vol.6, pp.587-590, 1972. ,
A common subunit structure in Clostridium botulinum type A, B and E toxins, Biochemical and Biophysical Research Communications, vol.48, issue.1, pp.108-112, 1972. ,
DOI : 10.1016/0006-291X(72)90350-6
Historical and current perspectives on Clostridium botulinum diversity, Research in Microbiology, vol.166, issue.4, pp.290-302, 2015. ,
DOI : 10.1016/j.resmic.2014.09.007