First isolation of Clostridium indolis in a patient with chronic osteitis: a case report and literature review of human infections related to Clostridium saccharolyticum group species

Romain Lotte (1, 2) , Laurène Lotte (1) , Philippe Bouvet (3) , Nicolas Degand (1) , Antonin Bal (1) , Michel Carles (4, 2) , Regis Bernard de Dompsure (1) , Michel-Robert Popoff (3) , Raymond Ruimy (2, 1)

1 CHU Nice - Centre Hospitalier Universitaire de Nice
2 C3M - Centre méditerranéen de médecine moléculaire
3 CNR - Centre National de Référence des Bactéries Anaérobies et Botulisme - National Reference Center Anaerobic Bacteria and Botulism
4 CHU - Hôpital Archet 2 [Nice]

Clostridium indolis is an anaerobic spore-forming Gram-positive bacillus belonging to the Clostridium saccharolyticum group. Its clinical significance in human remains poorly known. We describe the first case of osteitis related to C. indolis, identified by MALDI-TOF mass spectrometry and provide a literature review of human infections related to C. saccharolyticum group species.

Keywords: Osteitis; Clostridium; Emerging pathogen

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Toxicology

Romain Lotte, Laurène Lotte, Philippe Bouvet, Nicolas Degand, Antonin Bal, et al.. First isolation of Clostridium indolis in a patient with chronic osteitis: a case report and literature review of human infections related to Clostridium saccharolyticum group species. Anaerobe, 2016, 42, pp.44 - 49. ⟨10.1016/j.anaerobe.2016.08.001⟩. ⟨pasteur-01787653⟩