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Journal articles
Questions on viral population biology to complete dengue puzzle
Abstract : The mechanisms driving the current evolution of dengue remain unclear. We argue that disregarding the population biology of viruses has been a limiting factor, and present a hypothetical framework based on viral population biology. This allows us to pinpoint three flaws that need to be addressed: (1) a large underestimation of the viral polymorphism within populations; (2) a disregard of viral loci other than that encoding the antigenic envelope; and (3) the neglect of host-driven selection, especially that of vector-driven selection.
Cited literature [46 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01713414
Contributor : Marie Demeslay Gougam <>
Submitted on : Tuesday, February 20, 2018 - 3:25:49 PM
Last modification on : Tuesday, March 31, 2020 - 11:48:03 AM
Long-term archiving on: : Monday, May 21, 2018 - 1:24:01 PM
Contributor : Marie Demeslay Gougam <>
Submitted on : Tuesday, February 20, 2018 - 3:25:49 PM
Last modification on : Tuesday, March 31, 2020 - 11:48:03 AM
Long-term archiving on: : Monday, May 21, 2018 - 1:24:01 PM
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Questions on viral population....
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