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Journal articles
Glycosylphosphatidylinositol-Anchored Ecm33p Influences Conidial Cell Wall Biosynthesis in Aspergillus fumigatus
Abstract : ECM33 encodes a glycosylphosphatidylinositol-anchored protein whose orthologs in yeast are essential for sporulation. Aspergillus fumigatus Ecm33p is unique and has an apparent mass of 55 kDa. Disruption of A. fumigatus ECM33 results in a mutant with several morphogenetic aberrations, including the following: (i) a defect in conidial separation, (ii) an increase in the diameter of the conidia of the mutant associated with an increase in the concentration of the cell wall chitin, (iii) conidia that were sensitive to the absence of aeration during long-term storage, and (iv) conidia that were more resistant to killing by phagocytes, whereas the mycelium was more easily killed by neutrophils.
https://hal-pasteur.archives-ouvertes.fr/pasteur-01710053
Contributor : Nirina Andriakoto <>
Submitted on : Thursday, February 15, 2018 - 3:26:07 PM
Last modification on : Thursday, May 28, 2020 - 12:58:02 PM
Contributor : Nirina Andriakoto <>
Submitted on : Thursday, February 15, 2018 - 3:26:07 PM
Last modification on : Thursday, May 28, 2020 - 12:58:02 PM
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