Prokaryotic toxin???antitoxin stress response loci, Nature Reviews Microbiology, vol.116, issue.5, pp.371-382, 2005. ,
DOI : 10.1016/S0092-8674(03)01034-1
Bacterial Toxin???Antitoxin Systems: More Than Selfish Entities?, PLoS Genetics, vol.25, issue.3, 2009. ,
DOI : 10.1371/journal.pgen.1000437.t002
Toxin-Antitoxin Systems in Bacteria and Archaea, Annual Review of Genetics, vol.45, issue.1, pp.61-79, 2011. ,
DOI : 10.1146/annurev-genet-110410-132412
The phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair, Proceedings of the National Academy of Sciences, vol.177, issue.14, pp.894-899, 2009. ,
DOI : 10.1093/nar/26.4.1107
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes, Nucleic Acids Research, vol.33, issue.3, pp.966-976, 2005. ,
DOI : 10.1093/nar/gki201
Automated Discovery and Phylogenetic Analysis of New Toxin-Antitoxin Systems, BMC Microbiology, vol.8, issue.1, 2008. ,
DOI : 10.1186/1471-2180-8-104
Diversity of bacterial type II toxin???antitoxin systems: a comprehensive search and functional analysis of novel families, Nucleic Acids Research, vol.293, issue.13, pp.5513-5525, 2011. ,
DOI : 10.1371/journal.pbio.0030248
Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution, PLoS Genetics, vol.75, issue.12, 2009. ,
DOI : 10.1371/journal.pgen.1000767.s010
Bacterial Programmed Cell Death and Multicellular Behavior in Bacteria, PLoS Genetics, vol.7, issue.10, 2006. ,
DOI : 1462-2912(2005)007[1065:SCDIPM]2.0.CO;2
Toxin???antitoxin systems: why so many, what for?, Current Opinion in Microbiology, vol.13, issue.6, pp.781-785, 2010. ,
DOI : 10.1016/j.mib.2010.10.006
Toxin???antitoxin Loci as Stress-response-elements: ChpAK/MazF and ChpBK Cleave Translated RNAs and are Counteracted by tmRNA, Journal of Molecular Biology, vol.332, issue.4, pp.809-819, 2003. ,
DOI : 10.1016/S0022-2836(03)00922-7
URL : http://orbit.dtu.dk/en/publications/toxinantitoxin-loci-as-stressresponseelements-chpakmazf-and-chpbk-cleave-translated-rnas-and-are-counteracted-by-tmrna(192cd46c-a124-4ed0-88e1-5755bc2b6a3b).html
Specialized Persister Cells and the Mechanism of Multidrug Tolerance in Escherichia coli, Journal of Bacteriology, vol.186, issue.24, pp.8172-8180, 2004. ,
DOI : 10.1128/JB.186.24.8172-8180.2004
Persister Cells, Annual Review of Microbiology, vol.64, issue.1, pp.357-372, 2010. ,
DOI : 10.1146/annurev.micro.112408.134306
MazF, an mRNA Interferase, Mediates Programmed Cell Death during Multicellular Myxococcus Development, Cell, vol.132, issue.1, pp.55-66, 2008. ,
DOI : 10.1016/j.cell.2007.11.044
URL : https://doi.org/10.1016/j.cell.2007.11.044
Functional Interactions between Coexisting Toxin-Antitoxin Systems of the ccd Family in Escherichia coli O157:H7, Journal of Bacteriology, vol.189, issue.7, pp.2712-2719, 2007. ,
DOI : 10.1128/JB.01679-06
Chromosomal Toxin-Antitoxin Systems May Act as Antiaddiction Modules, Journal of Bacteriology, vol.190, issue.13, pp.4603-4609, 2008. ,
DOI : 10.1128/JB.00357-08
Comparative Analysis of Superintegrons: Engineering Extensive Genetic Diversity in the Vibrionaceae, Genome Research, vol.13, issue.3, pp.428-442, 2003. ,
DOI : 10.1101/gr.617103
Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection, Molecular Microbiology, vol.267, issue.6, pp.1588-1605, 2007. ,
DOI : 10.1128/jb.177.12.3451-3454.1995
A Toxin???Antitoxin System Promotes the Maintenance of an Integrative Conjugative Element, PLoS Genetics, vol.53, issue.1, 2009. ,
DOI : 10.1371/journal.pgen.1000439.t004
The SXT Conjugative Element and Linear Prophage N15 Encode Toxin-Antitoxin-Stabilizing Systems Homologous to the tad-ata Module of the Paracoccus aminophilus Plasmid pAMI2, Journal of Bacteriology, vol.189, issue.5, pp.1983-1997, 2007. ,
DOI : 10.1128/JB.01610-06
Integrons, Annual Review of Genetics, vol.44, issue.1, pp.141-166, 2010. ,
DOI : 10.1146/annurev-genet-102209-163504
URL : https://hal.archives-ouvertes.fr/hal-00535771
A Distinctive Class of Integron in the Vibrio cholerae Genome, Science, vol.280, issue.5363, pp.605-608, 1998. ,
DOI : 10.1126/science.280.5363.605
Integrons: mobilizable platforms that promote genetic diversity in bacteria, Trends in Microbiology, vol.15, issue.7, pp.301-309, 2007. ,
DOI : 10.1016/j.tim.2007.05.004
The SOS Response Controls Integron Recombination, Science, vol.9, issue.5, p.1034, 2009. ,
DOI : 10.1016/j.mib.2006.07.002
URL : https://hal.archives-ouvertes.fr/hal-00409031
Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons, Mobile DNA, vol.2, issue.1, pp.6-10, 2011. ,
DOI : 10.1101/gr.849004
URL : https://hal.archives-ouvertes.fr/inserm-00598347
ABSTRACT, Antimicrobial Agents and Chemotherapy, vol.55, issue.5, pp.2438-2441, 2011. ,
DOI : 10.1128/AAC.01549-10
Connecting Environment and Genome Plasticity in the Characterization of Transformation-Induced SOS Regulation and Carbon Catabolite Control of the Vibrio cholerae Integron Integrase, Journal of Bacteriology, vol.194, issue.7, pp.1659-1667, 2012. ,
DOI : 10.1128/JB.05982-11
Identification of VCR, a repeated sequence associated with a locus encoding a hemagglutinin in Vibrio cholerae O1., Journal of Bacteriology, vol.176, issue.17, pp.5450-5458, 1994. ,
DOI : 10.1128/jb.176.17.5450-5458.1994
Use of chromosomal integron arrays as a phylogenetic typing system for Vibrio cholerae pandemic strains, Microbiology, vol.153, issue.5, pp.1488-1498, 2007. ,
DOI : 10.1099/mic.0.2006/001065-0
A Recalibrated Molecular Clock and Independent Origins for the Cholera Pandemic Clones, PLoS ONE, vol.13, issue.12, 2008. ,
DOI : 10.1371/journal.pone.0004053.s016
Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae, Proceedings of the National Academy of Sciences, vol.9, issue.4, pp.15442-15447, 2009. ,
DOI : 10.1093/bib/bbn017
Development of simple and rapid PCR-fingerprinting methods for Vibrio cholerae on the basis of genetic diversity of the superintegron, Journal of Applied Microbiology, vol.109, pp.304-312, 2010. ,
DOI : 10.1111/j.1364-5072.2009.04658.x
Structural variation of the superintegron in the toxigenic Vibrio cholerae O1 El Tor, Biomed. Environ. Sci, vol.24, pp.579-592, 2011. ,
Inverse Correlation between Promoter Strength and Excision Activity in Class 1 Integrons, PLoS Genetics, vol.314, issue.1, 2010. ,
DOI : 10.1371/journal.pgen.1000793.s004
URL : https://hal.archives-ouvertes.fr/inserm-00533193
superintegron encode mRNA cleaving enzymes and can stabilize plasmids, Molecular Microbiology, vol.12, issue.2, pp.397-411, 2006. ,
DOI : 10.1016/S1097-2765(03)00402-7
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2958.2006.05385.x/pdf
Characterization of a higBA Toxin-Antitoxin Locus in Vibrio cholerae, Journal of Bacteriology, vol.189, issue.2, pp.491-500, 2007. ,
DOI : 10.1128/JB.00909-06
The Three Vibrio cholerae Chromosome II-Encoded ParE Toxins Degrade Chromosome I following Loss of Chromosome II, Journal of Bacteriology, vol.193, issue.3, pp.611-619, 2011. ,
DOI : 10.1128/JB.01185-10
Topography of cotransducible arginine mutations in Escherichia coli K-12, Genetics, vol.51, pp.167-179, 1965. ,
Bacterial resistance evolution by recruitment of super-integron gene cassettes, Molecular Microbiology, vol.43, issue.6, pp.1657-1669, 2002. ,
DOI : 10.1099/00222615-46-5-398
RcsB plays a central role in H-NS-dependent regulation of motility and acid stress resistance in Escherichia coli, Research in Microbiology, vol.161, issue.5, pp.363-371, 2010. ,
DOI : 10.1016/j.resmic.2010.04.002
Regulatory role of UvrY in adaptation of Photorhabdus luminescens growth inside the insect, Environmental Microbiology, vol.66, issue.5, pp.1118-1134, 2008. ,
DOI : 10.1099/mic.0.28136-0
Construction of a Vibrio splendidus Mutant Lacking the Metalloprotease Gene vsm by Use of a Novel Counterselectable Suicide Vector, Applied and Environmental Microbiology, vol.73, issue.3, pp.777-784, 2007. ,
DOI : 10.1128/AEM.02147-06
Correlation between Detection of a Plasmid and High-Level Virulence of Vibrio nigripulchritudo, a Pathogen of the Shrimp Litopenaeus stylirostris, Applied and Environmental Microbiology, vol.74, issue.10, pp.3038-3047, 2008. ,
DOI : 10.1128/AEM.02680-07
Conserved small RNAs govern replication and incompatibility of a diverse new plasmid family from marine bacteria, Nucleic Acids Research, vol.84, issue.3, pp.1004-1013, 2011. ,
DOI : 10.1073/pnas.84.24.8849
The antidote and autoregulatory functions of the F plasmid CcdA protein: a genetic and biochemical survey, Molecular and General Genetics MGG, vol.54, issue.6, pp.530-538, 1994. ,
DOI : 10.1007/BF00583904
Lon-dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid-free segregant bacteria, Molecular Microbiology, vol.174, issue.6, pp.1151-1157, 1994. ,
DOI : 10.1007/BF00427044
Integron cassette insertion: a recombination process involving a folded single strand substrate, The EMBO Journal, vol.91, issue.24, pp.4356-4367, 2005. ,
DOI : 10.1038/sj.emboj.7600434
URL : http://emboj.embopress.org/content/embojnl/24/24/4356.full.pdf
Regulation of proteolysis of the stationaryphase sigma factor RpoS, J. Bacteriol, vol.180, pp.1154-1158, 1998. ,
The Vibrio cholerae O1 chromosomal integron, Microbiology, vol.146, issue.10, pp.2605-2612, 2000. ,
DOI : 10.1099/00221287-146-10-2605
URL : http://mic.microbiologyresearch.org/deliver/fulltext/micro/146/10/1462605a.pdf?itemId=/content/journal/micro/10.1099/00221287-146-10-2605&mimeType=pdf&isFastTrackArticle=
Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes, Journal of Molecular Biology, vol.226, issue.3, pp.735-745, 1992. ,
DOI : 10.1016/0022-2836(92)90629-X
Complete genome sequence of Vibrio fischeri: A symbiotic bacterium with pathogenic congeners, Proceedings of the National Academy of Sciences, vol.306, issue.5699, pp.3004-3009, 2005. ,
DOI : 10.1126/science.1102218
Cell density-dependent modulation of the Vibrio fischeri luminescence system in the absence of autoinducer and LuxR protein., Journal of Bacteriology, vol.174, issue.8, pp.2440-2448, 1992. ,
DOI : 10.1128/jb.174.8.2440-2448.1992
Conjugative DNA Transfer Induces the Bacterial SOS Response and Promotes Antibiotic Resistance Development through Integron Activation, PLoS Genetics, vol.310, issue.Pt 9, 2010. ,
DOI : 10.1371/journal.pgen.1001165.s006
Efficiency of Recombination Reactions Catalyzed by Class 1 Integron Integrase IntI1, Journal of Bacteriology, vol.183, issue.8, pp.2535-2542, 2001. ,
DOI : 10.1128/JB.183.8.2535-2542.2001
The Yersinia pestis Chromosome Encodes Active Addiction Toxins, Journal of Bacteriology, vol.192, issue.14, pp.3669-3677, 2010. ,
DOI : 10.1128/JB.00336-10
Plasmid Addiction Genes of Bacteriophage P1: doc, which Causes Cell Death on Curing of Prophage, and phd, which Prevents Host Death when Prophage is Retained, Journal of Molecular Biology, vol.233, issue.3, pp.414-428, 1993. ,
DOI : 10.1006/jmbi.1993.1521
Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit, Proceedings of the National Academy of Sciences, vol.32, issue.4, pp.5885-5890, 2008. ,
DOI : 10.1016/0092-8674(83)90314-8
Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems, Structure, vol.18, issue.8, pp.996-1010, 2010. ,
DOI : 10.1016/j.str.2010.04.018
Modular Organization of the Phd Repressor/Antitoxin Protein, Journal of Bacteriology, vol.186, issue.9, pp.2692-2698, 2004. ,
DOI : 10.1128/JB.186.9.2692-2698.2004
Characterization of the Phd Repressor-Antitoxin Boundary, Journal of Bacteriology, vol.187, issue.2, pp.765-770, 2005. ,
DOI : 10.1128/JB.187.2.765-770.2005
Stability and DNA Binding of the Phd Protein of the Phage P1 Plasmid Addiction System, Journal of Biological Chemistry, vol.264, issue.5, pp.2652-2657, 1999. ,
DOI : 10.1021/bi00056a022
Autoregulation of the Plasmid Addiction Operon of Bacteriophage P1, Journal of Biological Chemistry, vol.3, issue.31, pp.18705-18710, 1996. ,
DOI : 10.1016/0022-2836(80)90283-1
Corepression of the P1 addiction operon by Phd and Doc, J. Bacteriol, vol.180, pp.6342-6351, 1998. ,
Doc of Prophage P1 Is Inhibited by Its Antitoxin Partner Phd through Fold Complementation, Journal of Biological Chemistry, vol.7, issue.45, pp.30821-30827, 2008. ,
DOI : 10.1110/ps.03379804
Alternative interactions define gyrase specificity in the CcdB family, Molecular Microbiology, vol.33, issue.5, pp.965-978, 2012. ,
DOI : 10.1016/0378-1119(85)90120-9
CcdB, Journal of Biological Chemistry, vol.15, issue.8, pp.5606-5613, 2010. ,
DOI : 10.1111/j.1365-2958.1995.tb02278.x
F plasmid CcdB killer protein ccdB gene mutants coding for non-cytotoxic proteins which retain their regulatory functions, Molecular Microbiology, vol.11, issue.6, pp.1031-1037, 1995. ,
DOI : 10.1007/BF00261153
ParE2 Poisons DNA Gyrase via a Mechanism Distinct from Other Gyrase Inhibitors, Journal of Biological Chemistry, vol.174, issue.51, pp.40397-40408, 2010. ,
DOI : 10.1074/jbc.M109.014035
URL : http://www.jbc.org/content/285/51/40397.full.pdf
chromosome and in plasmid R1, FEMS Microbiology Letters, vol.74, issue.1, pp.51-58, 1998. ,
DOI : 10.1128/jb.172.11.6557-6567.1990
chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100., Journal of Bacteriology, vol.175, issue.21, pp.6850-6856, 1993. ,
DOI : 10.1128/jb.175.21.6850-6856.1993
Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium, Molecular Microbiology, vol.48, issue.5, pp.1419-1432, 2003. ,
DOI : 10.1128/jb.175.7.1900-1909.1993
The yefM-yoeB Toxin-Antitoxin Systems of Escherichia coli and Streptococcus pneumoniae: Functional and Structural Correlation, Journal of Bacteriology, vol.189, issue.4, pp.1266-1278, 2007. ,
DOI : 10.1128/JB.01130-06
Behavior of restriction-modification systems as selfish mobile elements and their impact on genome evolution, Nucleic Acids Research, vol.29, issue.18, pp.3742-3756, 2001. ,
DOI : 10.1093/nar/29.18.3742
A new family of mobilizable suicide plasmids based on broad host range R388 plasmid (IncW) and RP4 plasmid (IncP??) conjugative machineries and their cognate Escherichia coli host strains, Research in Microbiology, vol.156, issue.2, pp.245-255, 2005. ,
DOI : 10.1016/j.resmic.2004.09.007
The Highly Conserved TldD and TldE Proteins of Escherichia coli Are Involved in Microcin B17 Processing and in CcdA Degradation, Journal of Bacteriology, vol.184, issue.12, pp.3224-3231, 2002. ,
DOI : 10.1128/JB.184.12.3224-3231.2002
Depressed light emission by symbiotic Vibrio fischeri of the sepiolid squid Euprymna scolopes., Journal of Bacteriology, vol.172, issue.7, pp.3701-3706, 1990. ,
DOI : 10.1128/jb.172.7.3701-3706.1990
The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons, Proceedings of the National Academy of Sciences, vol.96, issue.5, pp.652-657, 2001. ,
DOI : 10.1073/pnas.96.5.2192
Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives, Gene, vol.102, issue.1, pp.75-78, 1991. ,
DOI : 10.1016/0378-1119(91)90541-I
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors, Gene, vol.33, issue.1, pp.103-119, 1985. ,
DOI : 10.1016/0378-1119(85)90120-9
Positive-selection vectors using the F plasmid ccdB killer gene, Gene, vol.148, issue.1, pp.71-74, 1994. ,
DOI : 10.1016/0378-1119(94)90235-6
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter., Journal of Bacteriology, vol.177, issue.14, pp.4121-4130, 1995. ,
DOI : 10.1128/jb.177.14.4121-4130.1995
The sites of action of the two copy number control functions of plasmid R1, MGG Molecular & General Genetics, vol.124, issue.3, pp.486-493, 1982. ,
DOI : 10.1007/BF00332633
Regulation of ribosomal RNA promoters with a synthetic lac operator., Proceedings of the National Academy of Sciences, vol.81, issue.22, pp.6929-6933, 1984. ,
DOI : 10.1073/pnas.81.22.6929