Skip to Main content Skip to Navigation
Journal articles

Genome Microevolution of Chikungunya Viruses Causing the Indian Ocean Outbreak

Isabelle Schuffenecker 1 Isabelle Iteman 2 Alain Michault 3 Severine Murri 1 Lionel Frangeul 4 Marie-Christine Vaney 5 Rachel Lavenir 2 Nathalie Pardigon 6 Jean-Marc Rey 7 François Pettinelli 8 Leon Biscornet 9 Laure Diancourt 2 Stephanie Michel 1 Stéphane Duquerroy 10, 5 Ghislaine Guigon 2 Marie-Pascale Frenkiel 6 Anne-Claire Bréhin 6 Nadège Cubito 1 Philippe Desprès 6 Frank Kunst 11 Félix A. Rey 5 Hervé Zeller 1 Sylvain Brisse 2
1 Centre national de Référence et Centre Collaborateur de l'OMS Arbovirus (CNR-CCOMS)
2 PF8 - Génotypage des Pathogènes et Santé Publique (Plate-forme)
3 GHSR - Groupe Hospitalier Sud Réunion
4 PF4 - Intégration et Analyse Génomique (Plate-Forme 4)
5 Virologie Structurale
6 Interactions Moléculaires Flavivirus-Hôtes
7 IPM - Unité de Virologie [Antananarivo, Madagascar]
8 CHM - Laboratory of the Hospital Centre of Mayotte
9 Seychelles Public Health Laboratory
10 UP11 - Université Paris-Sud - Paris 11
11 Génomique des Microorganismes Pathogènes
Abstract : A chikungunya virus outbreak of unprecedented magnitude is currently ongoing in Indian Ocean territories. In Réunion Island, this alphavirus has already infected about one-third of the human population. The main clinical symptom of the disease is a painful and invalidating poly-arthralgia. Besides the arthralgic form, 123 patients with a confirmed chikungunya infection have developed severe clinical signs, i.e., neurological signs or fulminant hepatitis.
Keywords : SEMLIKI-FOREST-VIRUS ONYONG-NYONG VIRUSES ROSS RIVER CHOLESTEROL DEPENDENCE SEQUENCE ALIGNMENT DISEASE FEVER IDENTIFICATION
Document type :
Journal articles
Complete list of metadatas

Cited literature [42 references]  Display  Hide  Download
https://hal-pasteur.archives-ouvertes.fr/pasteur-01659363
Contributor : Nathalie Pardigon <>
Submitted on : Friday, December 8, 2017 - 12:37:09 PM
Last modification on : Wednesday, October 14, 2020 - 4:02:17 AM

File

Vignette du document
journal.pmed.0030263.PDF
Publication funded by an institution

Licence

Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

PASTEUR | CNRS | RIIP | RIIP_MADAGASCAR

Citation

Isabelle Schuffenecker, Isabelle Iteman, Alain Michault, Severine Murri, Lionel Frangeul, et al.. Genome Microevolution of Chikungunya Viruses Causing the Indian Ocean Outbreak. PLoS Medicine, Public Library of Science, 2006, 3 (7), pp.e263. ⟨10.1371/journal.pmed.0030263⟩. ⟨pasteur-01659363⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

281

Files downloads

382