1. Hz and H. , 20 (s, 1H, NH) 13 C NMR (75 MHz, DMSO-d 6 ) ?: 11, p.29

. Dione, 75 mg, 0.403 mmol) and 3-phenoxybenzoic acid (129.49 mg, 0.605 mmol) in dry CH 2 Cl 2 (10 mL) was added EDC (125.12 mg, 0.806 mmol) and 4-DMAP (1.32 mg) at room temperature under argon. The reaction mixture was stirred overnight

. Ph, C (piperidin-2-yl) cannot be found. HRMS (ESI): calculated for, p.78

A. Zumla, P. Nahid, and S. T. Cole, Advances in the development of new tuberculosis drugs and treatment regimens, Nature Reviews Drug Discovery, vol.109, issue.5, pp.388-404, 2013.
DOI : 10.1073/pnas.1205735109

A. Koul, E. Arnoult, N. Lounis, J. Guillemont, and K. Andries, The challenge of new drug discovery for tuberculosis, Nature, vol.64, issue.7331, pp.483-490, 2011.
DOI : 10.1146/annurev.micro.112408.134043

Q. S. Cui, W. Shin, Y. Luo, J. Tian, H. Cui et al., Thymidylate Kinase: An Old Topic Brings New Perspectives, Current Medicinal Chemistry, vol.20, issue.10, pp.1286-1305, 2013.
DOI : 10.2174/0929867311320100006

G. Martínez-botella, J. T. Loch, O. M. Green, S. P. Kawatkar, N. B. Olivier et al., Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK), Bioorganic & Medicinal Chemistry Letters, vol.23, issue.1, pp.169-173, 2013.
DOI : 10.1016/j.bmcl.2012.10.128

S. Kova?ková, M. Dra?ínský, and D. Rejman, The synthesis of piperidine nucleoside analogs???a comparison of several methods to access the introduction of nucleobases, Tetrahedron, vol.67, issue.7, pp.1485-1500, 2011.
DOI : 10.1016/j.tet.2010.12.029

B. Bernet, U. Piantini, and A. Vasella, Determination of the gauche effect of 3-acetamido- and 3-acetoxy-piperidine and -tetrahydropyran by 1H-n.m.r. spectroscopy, Carbohydrate Research, vol.204, pp.11-25, 1990.
DOI : 10.1016/0008-6215(90)84017-O

S. A. Defrees, K. S. Reddy, and J. M. Cassady, A Selective and Efficient Method for the Deprotection of N-Benzyloxymethyl (BOM) Protecting Groups from Pyrimidine and Dihydropyrimidine Ring Systems, Synthetic Communications, vol.1983, issue.2, pp.213-220, 1988.
DOI : 10.1055/s-1983-30301

C. Blondin, L. Serina, L. Wiesmuller, A. M. Gilles, and O. Barzu, Improved Spectrophotometric Assay of Nucleoside Monophosphate Kinase Activity Using the Pyruvate Kinase/Lactate Dehydrogenase Coupling System, Analytical Biochemistry, vol.220, issue.1, pp.219-221, 1994.
DOI : 10.1006/abio.1994.1326