L. Y. Al-ayadhi, Altered oxytocin and vasopressin levels in autistic children in Central Saudi Arabia, Neurosciences, vol.10, pp.47-50, 2005.

S. Alexander, A. Mathie, and J. Peters, G PROTEIN-COUPLED RECEPTORS, British Journal of Pharmacology, vol.164, pp.5-113, 2011.
DOI : 10.1111/j.1476-5381.2011.01649_3.x

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315628

E. Anagnostou, L. Soorya, W. Chaplin, J. Bartz, D. Halpern et al., Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial, Molecular Autism, vol.3, issue.1, p.16, 2012.
DOI : 10.1038/nn0602-849

E. Andari, J. R. Duhamel, T. Zalla, E. Herbrecht, M. Leboyer et al., Promoting social behavior with oxytocin in high-functioning autism spectrum disorders, Proceedings of the National Academy of Sciences of the United States of America, pp.4389-4394, 2010.
DOI : 10.1192/bjp.187.3.262

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840168

A. Aneja and E. Tierney, Autism: The role of cholesterol in treatment, International Review of Psychiatry, vol.63, issue.1, pp.165-170, 2008.
DOI : 10.1201/b14120-72

R. Angelopoulou, G. Lavranos, and P. Manolakou, Establishing sexual dimorphism in human, Collegium Antropologicum, vol.30, pp.653-658, 2006.

E. Asano, D. C. Chugani, O. Muzik, M. Behen, J. Janisse et al., Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction, Neurology, vol.57, issue.7, pp.1269-1277, 2001.
DOI : 10.1212/WNL.57.7.1269

H. Asperger, Autistic psychopathy' in childhood (trans. and annotated by U. Firth), Autism and Asperger's syndrome, pp.37-92, 1991.
DOI : 10.1017/cbo9780511526770.002

B. Auyeung and S. Baron-cohen, Fetal Testosterone in Mind: Implications for Autism, Multiple origins of sex differences in brain, pp.123-137, 2013.
DOI : 10.1007/978-3-642-33721-5_9

B. Auyeung, S. Baron-cohen, E. Ashwin, R. Knickmeyer, K. Taylor et al., Fetal testosterone and autistic traits, British Journal of Psychology, vol.35, issue.1, pp.1-22, 2009.
DOI : 10.1016/0002-9378(84)90679-3

B. Auyeung, K. Taylor, G. Hackett, and S. Baron-cohen, Research Foetal testosterone and autistic traits in 18 to 24- month-old children, Molecular Autism, vol.1, pp.1-8, 2010.
DOI : 10.1186/2040-2392-1-11

URL : http://doi.org/10.1186/2040-2392-1-11

H. M. Azzam, H. Sayyah, S. Youssef, H. Lotfy, I. A. Abdelhamid et al., Autism and vitamin D, Middle East Current Psychiatry, vol.22, issue.1, pp.9-14, 2015.
DOI : 10.1097/01.XME.0000457269.05570.78

S. Baieli, L. Pavone, C. Meli, A. Fiumara, and M. Coleman, Autism and phenylketonuria, Journal of Autism and Developmental Disorders, vol.33, issue.2, pp.201-204, 2003.
DOI : 10.1023/A:1022999712639

M. Barnevik-olsson, C. Gillberg, and E. Fernell, Prevalence of autism in children born to Somali parents living in Sweden: a brief report, Developmental Medicine & Child Neurology, vol.2, issue.8, pp.598-601, 2008.
DOI : 10.1017/S0033291700057810

S. Baron-cohen, The extreme male brain theory of autism, Trends in Cognitive Sciences, vol.6, issue.6, pp.248-254, 2002.
DOI : 10.1016/S1364-6613(02)01904-6

S. Baron-cohen, Testing the extreme male brain (EMB) theory of autism: Let the data speak for themselves, Cognitive Neuropsychiatry, vol.10, issue.1, pp.77-81, 2005.
DOI : 10.1080/13546800344000336

S. Baron-cohen, B. Auyeung, B. Nørgaard-pedersen, D. M. Hougaard, M. W. Abdallah et al., Elevated fetal steroidogenic activity in autism, Molecular Psychiatry, vol.27, issue.3, pp.369-376, 2015.
DOI : 10.1111/1469-7610.00187

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184868

S. Bejerot and J. M. Eriksson, Sexuality and Gender Role in Autism Spectrum Disorder: A Case Control Study, PLoS ONE, vol.62, issue.1, p.87961, 2014.
DOI : 10.1371/journal.pone.0087961.s002

S. Bejerot, J. M. Eriksson, S. Bonde, K. Carlstr?-om, M. B. Humble et al., The extreme male brain revisited: gender coherence in adults with autism spectrum disorder, The British Journal of Psychiatry, vol.201, issue.2, pp.116-123, 2012.
DOI : 10.1192/bjp.bp.111.097899

A. Bener, A. O. Khattab, and M. M. Dabbagh, Is high prevalence of Vitamin D deficiency evidence for autism disorder?: In a highly endogamous population, Journal of Pediatric Neurosciences, vol.9, issue.3, p.227, 2014.
DOI : 10.4103/1817-1745.147574

E. Berry-kravis, R. Levin, H. Shah, S. Mathur, J. C. Darnell et al., Cholesterol levels in Fragile X syndrome, American Journal of Medical Genetics Part A, vol.31, issue.9338, pp.379-384, 2015.
DOI : 10.1002/ajmg.1320310402

V. Bitsika, C. F. Sharpley, J. A. Sweeney, and J. R. Mcfarlane, HPA and SAM axis responses as correlates of self- vs parental ratings of anxiety in boys with an Autistic Disorder, Physiology & Behavior, vol.127, pp.1-7, 2014.
DOI : 10.1016/j.physbeh.2013.12.011

R. Blassberg, J. I. Macrae, J. Briscoe, and J. Jacob, Reduced cholesterol levels impair Smoothened activation in Smith???Lemli???Opitz syndrome, Human Molecular Genetics, vol.25, issue.4, pp.693-705, 2016.
DOI : 10.1093/hmg/ddv507

URL : https://academic.oup.com/hmg/article-pdf/25/4/693/7145650/ddv507.pdf

P. F. Bolton and P. D. Griffiths, Association of tuberous sclerosis of temporal lobes with autism and atypical autism. The Lancet, pp.392-395, 1997.

M. Brosnan, J. Turner-cobb, Z. Munro-naan, and D. Jessop, Absence of a normal Cortisol Awakening Response (CAR) in adolescent males with Asperger Syndrome (AS), Psychoneuroendocrinology, vol.34, issue.7, 2009.
DOI : 10.1016/j.psyneuen.2009.02.011

W. T. Brown, E. Friedman, E. C. Jenkins, J. Brooks, K. Wisniewski et al., Association of fragile X syndrome with autism. The Lancet, pp.319-100, 1982.

I. Bukelis, F. D. Porter, A. W. Zimmerman, and E. Tierney, Smith-Lemli-Opitz Syndrome and Autism Spectrum Disorder, American Journal of Psychiatry, vol.164, issue.11, pp.1655-1661, 2007.
DOI : 10.1176/appi.ajp.2007.07020315

J. J. Cannell, Autism and vitamin D, Medical Hypotheses, vol.70, issue.4, pp.750-759, 2008.
DOI : 10.1016/j.mehy.2007.08.016

J. J. Cannell, Autism, will vitamin D treat core symptoms? Medical Hypotheses, pp.195-198, 2013.
DOI : 10.1016/j.mehy.2013.05.004

J. J. Cannell and W. B. Grant, What is the role of vitamin D in autism?, Dermato-Endocrinology, vol.4, issue.1, pp.199-204, 2012.
DOI : 10.1038/oby.2011.210

S. Christodoulou, T. Goula, A. Ververidis, and G. Drosos, Vitamin D and Bone Disease, BioMed Research International, vol.66, issue.3, p.396541, 2013.
DOI : 10.1097/RHU.0b013e3181b08f20

T. L. Clemens, J. S. Adams, S. L. Henderson, and M. F. Holick, INCREASED SKIN PIGMENT REDUCES THE CAPACITY OF SKIN TO SYNTHESISE VITAMIN D3, The Lancet, vol.319, issue.8263, pp.74-76, 1982.
DOI : 10.1016/S0140-6736(82)90214-8

M. Coleman and C. Gillberg, The autisms, 2012.
DOI : 10.1093/med/9780199732128.001.0001

B. A. Corbett and C. W. Schupp, The cortisol awakening response (CAR) in male children with autism spectrum disorder, Hormones and Behavior, vol.65, issue.4, pp.345-350, 2014.
DOI : 10.1016/j.yhbeh.2014.01.012

B. A. Corbett and D. Simon, Adolescence, stress and cortisol in autism spectrum disorders, OA Autism, vol.1, issue.1, 2013.
DOI : 10.13172/2052-7810-1-1-348

B. A. Corbett, S. Mendoza, M. Abdullah, J. A. Wegelin, and S. Levine, Cortisol circadian rhythms and response to stress in children with autism, Psychoneuroendocrinology, vol.31, issue.1, pp.31-59, 2006.
DOI : 10.1016/j.psyneuen.2005.05.011

B. A. Corbett, S. Mendoza, J. A. Wegelin, V. Carmean, and S. Levine, Variable cortisol circadian rhythms in children with autism and anticipatory stress, Journal of Psychiatry and Neuroscience, vol.33, pp.227-234, 2008.

B. A. Corbett, C. W. Schupp, and K. E. Lanni, Comparing biobehavioral profiles across two social stress paradigms in children with and without autism spectrum disorders, Molecular Autism, vol.3, issue.1, pp.1-10, 2012.
DOI : 10.1016/j.cpr.2009.01.003

URL : http://doi.org/10.1186/2040-2392-3-13

B. A. Corbett, C. W. Schupp, S. Levine, and S. Mendoza, Comparing cortisol, stress, and sensory sensitivity in children with autism, Autism Research, vol.29, issue.5, pp.39-49, 2009.
DOI : 10.1176/ajp.150.1.83

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698454

B. J. Crespi and P. L. Hurd, Genetically based correlates of serum oxytocin and testosterone in autism and schizotypy, Personality and Individual Differences, vol.79, pp.39-43, 2015.
DOI : 10.1016/j.paid.2015.01.052

A. Crider, R. Thakkar, A. O. Ahmed, and A. Pillai, Dysregulation of estrogen receptor beta (ER??), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects, Molecular Autism, vol.5, issue.1, p.46, 2014.
DOI : 10.1016/j.psyneuen.2008.12.007

M. H. De-souza-tostes, H. C. Polonini, W. F. Gattaz, N. R. Raposo, and E. B. Baptista, Low serum levels of 25- hydroxyvitamin D (25-OHD) in children with autism, Trends in Psychiatry and Psychotherapy, pp.161-163, 2012.

D. Vries, A. L. Noens, I. L. Cohen-kettenis, P. T. Van-berckelaer-onnes, I. A. Doreleijers et al., Autism Spectrum Disorders in Gender Dysphoric Children and Adolescents, Journal of Autism and Developmental Disorders, vol.11, issue.3, pp.930-936, 2010.
DOI : 10.1007/s10803-010-0935-9

M. J. Dealberto, Prevalence of autism according to maternal immigrant status and ethnic origin, Acta Psychiatrica Scandinavica, vol.121, issue.5, pp.339-348, 2011.
DOI : 10.1111/j.1600-0447.2010.01551.x

A. Diaz-stransky and E. Tierney, Cholesterol Use in Autism Treatment, comprehensive guide to autism, pp.2403-2425, 2014.
DOI : 10.1007/978-1-4614-4788-7_147

G. Domes, M. Heinrichs, E. Kumbier, A. Grossmann, K. Hauenstein et al., Effects of Intranasal Oxytocin on the Neural Basis of Face Processing in Autism Spectrum Disorder, Biological Psychiatry, vol.74, issue.3, pp.164-171, 2013.
DOI : 10.1016/j.biopsych.2013.02.007

J. Durdiakova, D. Ostatnikova, and P. Celec, Testosterone and its metabolites?modulators of brain functions, Acta Neurobiologiae Experimentalis, vol.71, pp.434-454, 2011.

I. Dziobek, S. M. Gold, O. T. Wolf, and A. Convit, Hypercholesterolemia in Asperger syndrome: Independence from lifestyle, obsessive???compulsive behavior, and social anxiety, Psychiatry Research, vol.149, issue.1-3, pp.321-324, 2007.
DOI : 10.1016/j.psychres.2006.02.003

A. A. Ehrhardt, H. F. Meyer-bahlburg, L. R. Rosen, J. F. Feldman, N. P. Veridiano et al., Sexual orientation after prenatal exposure to exogenous estrogen, Archives of Sexual Behavior, vol.28, issue.1, pp.57-77, 1985.
DOI : 10.1001/archpsyc.1973.01750340080013

D. Fein, S. Joy, L. Green, and L. Waterhouse, Autism and Pervasive Developmental Disorders, Neuropsychiatry, 1996.
DOI : 10.1016/B978-012267805-9/50011-0

E. Fernell, S. Bejerot, J. Westerlund, C. Miniscalco, H. Simila et al., Autism spectrum disorder and low vitamin D at birth: a sibling control study, Molecular Autism, vol.6, issue.1, 2015.
DOI : 10.1007/s12016-013-8361-3

URL : http://doi.org/10.1186/2040-2392-6-3

M. Fierro, A. J. Martinez, J. W. Harbison, and S. H. Hay, Smith-Lemli-Opitz Syndrome: Neuropathological and Ophthalmological Observations, Developmental Medicine & Child Neurology, vol.74, issue.1, pp.57-62, 1977.
DOI : 10.1001/archneur.1967.00470290100013

H. Gainer, M. Altstein, and M. H. Whitnall, Chapter 14 The cell biology and development of vasopressinergic and oxytocinergic neurons, Progress in Brain Research, vol.72, pp.153-161, 1987.
DOI : 10.1016/S0079-6123(08)60204-6

C. Gillberg, Debate and Argument: Is Autism a Pervasive Developmental Disorder?, Journal of Child Psychology and Psychiatry, vol.11, issue.7, pp.1169-1170, 1991.
DOI : 10.1007/BF01531665

URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1469-7610.1991.tb00357.x/pdf

I. C. Gillberg, C. Gillberg, and G. Ahls-en, AUTISTIC BEHAVIOUR AND ATTENTION DEFICITS IN TUBEROUS SCLEROSIS: A POPULATION-BASED STUDY, Developmental Medicine & Child Neurology, vol.8, issue.1, pp.50-56, 1994.
DOI : 10.1111/j.1469-8749.1994.tb11765.x

C. Gillberg, H. Schaumann, and I. C. Gillberg, Autism in immigrants: children born in Sweden to mothers born in Uganda, Journal of Intellectual Disability Research, vol.3, issue.2, pp.141-144, 1995.
DOI : 10.1192/bjp.137.5.410

G. Gimpl and F. Fahrenholz, The oxytocin receptor system: Structure, function, and regulation, Physiological Reviews, vol.81, pp.629-683, 2001.

G. Gimpl, J. Reitz, S. Brauer, and C. Trossen, Oxytocin receptors: ligand binding, signalling and cholesterol dependence, Progress in Brain Research, vol.170, pp.193-204, 2008.
DOI : 10.1016/S0079-6123(08)00417-2

Z. L. Gong, C. M. Luo, L. Wang, L. Shen, F. Wei et al., Serum 25-hydroxyvitamin D levels in Chinese children with autism spectrum disorders, NeuroReport, vol.25, pp.23-27, 2014.
DOI : 10.1097/WNR.0000000000000034

R. Goodman and H. Richards, Child and adolescent psychiatric presentations of second-generation Afro-Caribbeans in Britain, The British Journal of Psychiatry, vol.167, issue.3, pp.362-369, 1995.
DOI : 10.1192/bjp.167.3.362

W. B. Grant and J. J. Cannell, Autism prevalence in the United States with respect to solar UV-B doses: An ecological study, Dermato-Endocrinology, vol.23, issue.1, pp.159-164, 2013.
DOI : 10.3109/10428199609054835

W. B. Grant and C. M. Soles, Epidemiologic evidence for supporting the role of maternal vitamin D deficiency as a risk factor for the development of infantile autism, Dermato-Endocrinology, vol.13, issue.4, pp.223-228, 2009.
DOI : 10.1016/j.mehy.2007.08.016

L. Green, D. Fein, C. Modahl, C. Feinstein, L. Waterhouse et al., Oxytocin and autistic disorder: alterations in peptide forms, Biological Psychiatry, vol.50, issue.8, pp.609-613, 2001.
DOI : 10.1016/S0006-3223(01)01139-8

J. J. Green and E. Hollander, Autism and oxytocin: New developments in translational approaches to therapeutics, Neurotherapeutics, vol.5, issue.3, pp.250-257, 2010.
DOI : 10.1007/s12519-009-0033-2

URL : https://link.springer.com/content/pdf/10.1016%2Fj.nurt.2010.05.006.pdf

A. J. Guastella, S. L. Einfeld, K. M. Gray, N. J. Rinehart, B. J. Tonge et al., Intranasal Oxytocin Improves Emotion Recognition for Youth with Autism Spectrum Disorders, Biological Psychiatry, vol.67, issue.7, pp.692-694, 2010.
DOI : 10.1016/j.biopsych.2009.09.020

M. L. Hediger, L. J. England, C. A. Molloy, F. Y. Kai, P. Manning-courtney et al., Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder, Journal of Autism and Developmental Disorders, vol.16, issue.2 Suppl, pp.848-856, 2008.
DOI : 10.1080/1028415X.2001.11747348

J. W. Hennessey and S. Levine, Stress, arousal, and the pituitary-adrenal system: A psychoendocrine hypothesis, 1979.

M. R. Herbert, Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders, Current Opinion in Neurology, vol.23, issue.2, pp.103-110, 2010.
DOI : 10.1097/WCO.0b013e328336a01f

J. P. Herman and W. E. Cullinan, Neurocircuitry of stress: central control of the hypothalamo???pituitary???adrenocortical axis, Trends in Neurosciences, vol.20, issue.2, pp.78-84, 1997.
DOI : 10.1016/S0166-2236(96)10069-2

M. F. Holick, Vitamin D Deficiency, New England Journal of Medicine, vol.357, issue.3, pp.266-281, 2007.
DOI : 10.1056/NEJMra070553

E. Hollander, Oxytocin Infusion Reduces Repetitive Behaviors in Adults with Autistic and Asperger's Disorders, Neuropsychopharmacology, vol.28, issue.1, pp.193-198, 2003.
DOI : 10.1038/sj.npp.1300021

URL : http://www.nature.com/npp/journal/v28/n1/pdf/1300021a.pdf

E. Hollander, J. Bartz, W. Chaplin, A. Phillips, J. Sumner et al., Oxytocin Increases Retention of Social Cognition in Autism, Biological Psychiatry, vol.61, issue.4, pp.498-503, 2007.
DOI : 10.1016/j.biopsych.2006.05.030

M. B. Humble, S. Gustafsson, and S. Bejerot, Low serum levels of 25-hydroxyvitamin D (25-OHD) among psychiatric out-patients in Sweden: Relations with season, age, ethnic origin and psychiatric diagnosis, The Journal of Steroid Biochemistry and Molecular Biology, vol.121, issue.1-2, pp.467-470, 2010.
DOI : 10.1016/j.jsbmb.2010.03.013

E. Ingudomnukul, S. Baron-cohen, S. Wheelwright, and R. Knickmeyer, Elevated rates of testosterone-related disorders in women with autism spectrum conditions, Hormones and Behavior, vol.51, issue.5, pp.597-604, 2007.
DOI : 10.1016/j.yhbeh.2007.02.001

F. Jia, B. Wang, L. Shan, Z. Xu, W. G. Staal et al., Core Symptoms of Autism Improved After Vitamin D Supplementation, PEDIATRICS, vol.135, issue.1, pp.196-198, 2015.
DOI : 10.1542/peds.2014-2121

URL : http://pediatrics.aappublications.org/content/pediatrics/135/1/e196.full.pdf

X. S. Jiang, C. A. Wassif, P. S. Backlund, L. Song, L. A. Holtzclaw et al., Activation of Rho GTPases in Smith???Lemli???Opitz syndrome: pathophysiological and clinical implications, Human Molecular Genetics, vol.19, issue.7, pp.1347-1357, 2010.
DOI : 10.1093/hmg/ddq011

M. Kalinowska, C. Castillo, and A. Francesconi, Quantitative Profiling of Brain Lipid Raft Proteome in a Mouse Model of Fragile X Syndrome, PLOS ONE, vol.21, issue.1, p.121464, 2015.
DOI : 10.1371/journal.pone.0121464.s002

R. K. Kana, L. E. Libero, C. P. Hu, H. D. Deshpande, and J. S. Colburn, Functional Brain Networks and White Matter Underlying Theory-of-Mind in Autism, Social Cognitive and Affective Neuroscience, vol.9, issue.1, pp.98-105, 2014.
DOI : 10.1093/scan/nss106

L. Kanner, Autistic disturbances of affective contact, Nervous Child, vol.2, pp.217-250, 1943.

D. V. Keen, F. D. Reid, and D. Arnone, Autism, ethnicity and maternal immigration, The British Journal of Psychiatry, vol.196, issue.4, pp.274-281, 2010.
DOI : 10.1192/bjp.bp.109.065490

URL : http://bjp.rcpsych.org/content/bjprcpsych/196/4/274.full.pdf

M. Kirkovski, P. G. Enticott, and P. B. Fitzgerald, A Review of the Role of Female Gender in Autism Spectrum Disorders, Journal of Autism and Developmental Disorders, vol.133, issue.6, pp.2584-2603, 2013.
DOI : 10.1037/0033-2909.133.6.976

R. Knickmeyer, S. Baron-cohen, B. A. Fane, S. Wheelwright, G. A. Mathews et al., Androgens and autistic traits: A study of individuals with congenital adrenal hyperplasia, Hormones and Behavior, vol.50, issue.1, pp.148-153, 2006.
DOI : 10.1016/j.yhbeh.2006.02.006

E. Ko?ovsk-a, G. Andorsd-ottir, P. Weihe, J. Halling, E. Fernell et al., Vitamin D in the General Population of Young Adults with Autism in the Faroe Islands, Journal of Autism and Developmental Disorders, vol.43, issue.supplement 1, pp.2996-3005, 2014.
DOI : 10.1111/1469-7610.00023

E. Ko?ovsk-a, E. Fernell, E. Billstedt, H. Minnis, and C. Gillberg, Vitamin D and autism: Clinical review, Research in Developmental Disabilities, vol.33, issue.5, pp.1541-1550, 2012.
DOI : 10.1016/j.ridd.2012.02.015

K. Kosidou, C. Dalman, L. Widman, S. Arver, B. K. Lee et al., Maternal polycystic ovary syndrome and the risk of autism spectrum disorders in the offspring: a population-based nationwide study in Sweden, Molecular Psychiatry, vol.12, issue.10, pp.1441-1448, 2016.
DOI : 10.1210/jc.2003-031122

P. Krajmer, D. Ikov-a, M. Spajdel, and D. Ostatn-ikov-a, Empathizing, systemizing, intuitive physics and folk psychology in boys with Asperger syndrome, Activitas Nervosa Superior Rediviva, vol.52, pp.57-61, 2010.

V. S. Kumar, Phenylketonuria with autism spectrum disorders: A case study, International Journal of Health Sciences and Research, vol.4, pp.308-312, 2014.

M. C. Lai, J. P. Lerch, D. L. Floris, A. N. Ruigrok, A. Pohl et al., Imaging sex/gender and autism in the brain: Etiological implications, Journal of Neuroscience Research, vol.18, issue.Pt 6, pp.380-397, 2017.
DOI : 10.1016/j.spen.2011.02.003

M. C. Lai, M. V. Lombardo, J. Suckling, A. N. Ruigrok, B. Chakrabarti et al., Biological sex affects the neurobiology of autism, Brain, vol.136, issue.9, pp.2799-2815, 2013.
DOI : 10.1093/brain/awt216

S. Lakatosova, S. Nurit, P. Anna, H. Veronika, R. Irina et al., Oxytocin but Not Testosterone Modulates Behavioral Patterns in Autism Spectrum Disorders, Open Journal of Medical Psychology, vol.03, issue.01, pp.48-53, 2013.
DOI : 10.4236/ojmp.2014.31006

M. Land-en, J. Wålinder, and B. Lundstr?-om, Prevalence, incidence and sex ratio of transsexualism, Acta Psychiatrica Scandinavica, vol.300, issue.4, pp.221-223, 1996.
DOI : 10.1007/978-3-642-73794-7_29

C. Lecis and M. Segatto, Cholesterol homeostasis imbalance and brain functioning: Neuro-logical disorders and behavioral consequences, Journal of Neurology and Neurological Disorders, vol.1, issue.1, 2014.

R. W. Lee and E. Tierney, Hypothesis: The Role of Sterols in Autism Spectrum Disorder, Autism Research and Treatment, vol.80, issue.1, 2011.
DOI : 10.1016/j.freeradbiomed.2006.09.006

D. J. Leffell and D. E. Brash, Sunlight and Skin Cancer, Scientific American, vol.275, issue.1, pp.52-59, 1996.
DOI : 10.1038/scientificamerican0796-52

A. Liberati, D. G. Altman, J. Tetzlaff, C. Mulrow, P. C. Gøtzsche et al., The PRISMA statement for reporting systematic reviews and metaanalyses of studies that evaluate health care interventions: Explanation and elaboration, Annals of Internal Medicine, vol.151, p.65, 2009.

C. Lord, M. Rutter, and A. Le-couteur, Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders, Journal of Autism and Developmental Disorders, vol.93, issue.5, pp.659-685, 1994.
DOI : 10.1016/S0387-7604(12)80166-5

S. Lydon, O. Healy, M. Roche, R. Henry, T. Mulhern et al., Salivary cortisol levels and challenging behavior in children with autism spectrum disorder, Research in Autism Spectrum Disorders, pp.78-92, 2015.
DOI : 10.1016/j.rasd.2014.10.020

J. Marcos, L. W. Guo, W. K. Wilson, F. D. Porter, and C. Shackleton, The implications of 7-dehydrosterol-7-reductase deficiency (Smith???Lemli???Opitz syndrome) to neurosteroid production, Steroids, vol.69, issue.1, pp.51-60, 2004.
DOI : 10.1016/j.steroids.2003.09.013

N. A. Meguid, A. F. Hashish, M. Anwar, and G. Sidhom, Reduced Serum Levels of 25-Hydroxy and 1,25-Dihydroxy Vitamin D in Egyptian Children with Autism, The Journal of Alternative and Complementary Medicine, vol.16, issue.6, pp.641-645, 2010.
DOI : 10.1089/acm.2009.0349

A. Meljon, G. L. Watson, Y. Wang, C. H. Shackleton, and W. J. Griffiths, Analysis by liquid chromatography???mass spectrometry of sterols and oxysterols in brain of the newborn Dhcr7??3-5/T93M mouse: A model of Smith???Lemli???Opitz syndrome, Biochemical Pharmacology, vol.86, issue.1, pp.43-55, 2013.
DOI : 10.1016/j.bcp.2013.03.003

M. Miller, K. L. Bales, S. L. Taylor, J. Yoon, C. M. Hostetler et al., Oxytocin and Vasopressin in Children and Adolescents With Autism Spectrum Disorders: Sex Differences and Associations With Symptoms, Autism Research, vol.59, issue.2, pp.91-102, 2013.
DOI : 10.1002/ana.20722

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657571

C. Modahl, D. Fein, L. Waterhouse, and N. Newton, Does oxytocin deficiency mediate social deficits in autism?, Journal of Autism and Developmental Disorders, vol.579, issue.Suppl., pp.449-451, 1992.
DOI : 10.1007/BF01048246

C. Modahl, L. A. Green, D. Fein, M. Morris, L. Waterhouse et al., Plasma oxytocin levels in autistic children, Biological Psychiatry, vol.43, issue.4, pp.270-277, 1998.
DOI : 10.1016/S0006-3223(97)00439-3

D. Moher, A. Liberati, J. Tetzlaff, and D. G. Altman, Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement, Annals of Internal Medicine, vol.151, issue.4, pp.264-269, 2009.
DOI : 10.7326/0003-4819-151-4-200908180-00135

C. A. Molloy, H. J. Kalkwarf, P. Manning-courtney, J. L. Mills, and M. L. Hediger, Plasma 25(OH)D concentration in children with autism spectrum disorder, Developmental Medicine & Child Neurology, vol.50, issue.No SS-1, pp.969-971, 2010.
DOI : 10.1111/j.1469-8749.2010.03704.x

G. A. Mostafa and L. Y. Ayadhi, Reduced serum concentrations of 25-hydroxy vitamin D in children with autism: Relation to autoimmunity, Journal of Neuroinflammation, vol.13, issue.1, p.201, 2012.
DOI : 10.1016/j.autrev.2012.07.007

R. Muhle, S. V. Trentacoste, and I. Rapin, The Genetics of Autism, PEDIATRICS, vol.113, issue.5, pp.472-486, 2004.
DOI : 10.1542/peds.113.5.e472

J. Netting, New autism gene plays key role in cholesterol synthesis. Spectrum. Accessed on 20 Retrieved from https://spectrumnews.org/news/new-autism- gene-plays-key-role-in-cholesterol-synthesis, 2013.

K. Nishimori, Y. Takayanagi, M. Yoshida, Y. Kasahara, L. J. Young et al., New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behaviour and control of energy balance, Progress in Brain Research, vol.170, pp.79-90, 2008.
DOI : 10.1016/S0079-6123(08)00408-1

O. Connor, T. G. Heron, J. Golding, J. Glover, and V. , Maternal antenatal anxiety and behavioural/emotional problems in children: a test of a programming hypothesis, Journal of Child Psychology and Psychiatry, vol.125, issue.7, pp.1025-1036, 2003.
DOI : 10.1016/0378-3782(89)90100-X

J. M. Opitz, E. Gilbert-barness, J. Ackerman, and A. Lowichik, CHOLESTEROL AND DEVELOPMENT: THE RSH ("SMITH-LEMLI-OPITZ") SYNDROME AND RELATED CONDITIONS, Pediatric Pathology & Molecular Medicine, vol.21, issue.2, pp.153-181, 2002.
DOI : 10.1080/pdp.21.2.153.181

R. P. Patrick and B. N. Ames, Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism, The FASEB Journal, vol.28, issue.6, pp.2398-2413, 2014.
DOI : 10.1096/fj.13-246546

URL : http://www.fasebj.org/content/28/6/2398.full.pdf

A. H. Payne and D. B. Hales, Overview of Steroidogenic Enzymes in the Pathway from Cholesterol to Active Steroid Hormones, Endocrine Reviews, vol.25, issue.6, pp.947-970, 2004.
DOI : 10.1210/er.2003-0030

J. Pearson, Disordered cholesterol metabolism in autism spectrum disorders sterol and genetic analyses Scholar Archive, paper 437 Retrieved 23rd Male predominance in autism: Neuroendocrine influences on arousal and social anxiety, Autism Research, vol.4, pp.163-176, 2010.

F. D. Porter, Smith???Lemli???Opitz syndrome: pathogenesis, diagnosis and management, European Journal of Human Genetics, vol.143, issue.5, pp.535-541, 2008.
DOI : 10.1002/ajmg.a.31901

M. B. Posserud, A. J. Lundervold, and C. Gillberg, Autistic features in a total population of 7-9-year-old children assessed by the ASSQ (Autism Spectrum Screening Questionnaire), Journal of Child Psychology and Psychiatry, vol.36, issue.4, pp.167-175, 2006.
DOI : 10.1002/mrdd.10029

E. Quattrocki and K. Friston, Autism, oxytocin and interoception, Neuroscience & Biobehavioral Reviews, vol.47, pp.410-430, 2014.
DOI : 10.1016/j.neubiorev.2014.09.012

URL : http://doi.org/10.1016/j.neubiorev.2014.09.012

A. Reversi, V. Rimoldi, S. Brambillasca, and B. Chini, Effects of cholesterol manipulation on the signaling of the human oxytocin receptor, AJP: Regulatory, Integrative and Comparative Physiology, vol.291, issue.4, pp.861-869, 2006.
DOI : 10.1152/ajpregu.00333.2006

A. L. Richdale and M. R. Prior, Urinary cortisol circadian rhythm in a group of high-functioning children with autism, Journal of Autism and Developmental Disorders, vol.1, issue.3, pp.433-447, 1992.
DOI : 10.1007/BF01048245

K. Saad, E. Hammad, A. A. Abdel-rahman, and K. M. Sobhy, Autistic Symptoms in Late Diagnosed Phenylketonuric Children in Upper Egypt, Journal of Neurology Research, vol.3, pp.122-129, 2013.
DOI : 10.4021/jnr221w

G. Saher and S. K. Stumpf, Cholesterol in myelin biogenesis and hypomyelinating disorders, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1851, issue.8, pp.1851-1083, 2015.
DOI : 10.1016/j.bbalip.2015.02.010

C. L. Schengrund, F. Ali-rahmani, and J. C. Ramer, Cholesterol, GM1, and Autism, Cholesterol , GM1, and autism, pp.1201-1207, 2012.
DOI : 10.1167/iovs.01-0886

M. Segatto, L. Trapani, D. Tunno, I. Sticozzi, C. Valacchi et al., Cholesterol Metabolism Is Altered in Rett Syndrome: A Study on Plasma and Primary Cultured Fibroblasts Derived from Patients, PLoS ONE, vol.45, issue.5, p.104834, 2014.
DOI : 10.1371/journal.pone.0104834.g005

S. Seneff, R. Davidson, and L. Mascitelli, Might cholesterol sulfate deficiency contribute to the development of autistic spectrum disorder? Medical Hypotheses, pp.213-217, 2012.

S. Seneff, R. M. Davidson, A. Lauritzen, A. Samsel, and G. Wainwright, A novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome, Theoretical Biology and Medical Modelling, vol.632, issue.9339, p.24, 2015.
DOI : 10.1001/jama.300.7.795

URL : http://doi.org/10.1186/s12976-015-0006-1

D. M. Sikora, K. Pettit-kekel, J. Penfield, L. S. Merkens, and R. D. Steiner, The near universal presence of autism spectrum disorders in children with Smith???Lemli???Opitz syndrome, American Journal of Medical Genetics Part A, vol.289, issue.14, pp.1511-1518, 2006.
DOI : 10.1002/ajmg.a.31294

E. Simonoff, A. Pickles, T. Charman, S. Chandler, T. Loucas et al., Psychiatric Disorders in Children With Autism Spectrum Disorders: Prevalence, Comorbidity, and Associated Factors in a Population-Derived Sample, Journal of the American Academy of Child & Adolescent Psychiatry, vol.47, issue.8, pp.921-929, 2008.
DOI : 10.1097/CHI.0b013e318179964f

S. L. Smalley, Autism and tuberous sclerosis, Journal of Autism and Developmental Disorders, vol.39, issue.3, pp.407-414, 1998.
DOI : 10.1001/archpsyc.1988.01800340081013

S. E. Sparks, C. A. Wassif, H. Goodwin, S. K. Conley, D. C. Lanham et al., Decreased cerebral spinal fluid neurotransmitter levels in Smith-Lemli-Opitz syndrome, Journal of Inherited Metabolic Disease, vol.1529, issue.1???3, pp.415-420, 2014.
DOI : 10.1016/S1388-1981(00)00159-1

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166510

L. Starck and A. L?-ovgren, Diagnosis of Smith-Lemli-Opitz syndrome from stored filter paper blood specimens, Archives of Disease in Childhood, vol.82, issue.6, pp.490-492, 2000.
DOI : 10.1136/adc.82.6.490

J. F. Strang, L. Kenworthy, A. Dominska, J. Sokoloff, L. E. Kenealy et al., Increased Gender Variance in Autism Spectrum Disorders and Attention Deficit Hyperactivity Disorder, Archives of Sexual Behavior, vol.7, issue.8, pp.1525-1533, 2014.
DOI : 10.1007/978-1-4614-7441-8_9

K. Strifert, The link between oral contraceptive use and prevalence in autism spectrum disorder, Medical Hypotheses, vol.83, issue.6, pp.718-725, 2014.
DOI : 10.1016/j.mehy.2014.09.026

M. Tachibana, K. Kagitani-shimono, I. Mohri, T. Yamamoto, W. Sanefuji et al., Long-Term Administration of Intranasal Oxytocin Is a Safe and Promising Therapy for Early Adolescent Boys with Autism Spectrum Disorders, Journal of Child and Adolescent Psychopharmacology, vol.23, issue.2, pp.123-127, 2013.
DOI : 10.1089/cap.2012.0048

H. Takagishi, T. Takahashi, T. Yamagishi, M. Shinada, K. Inukai et al., Salivary testosterone levels and autism-spectrum quotient in adults, Neuroendocrinology Letters, pp.31-837, 2010.

R. Taurines, C. Schwenck, B. Lyttwin, M. Schecklmann, T. Jans et al., Oxytocin plasma concentrations in children and adolescents with autism spectrum disorder: correlation with autistic symptomatology, ADHD Attention Deficit and Hyperactivity Disorders, vol.58, issue.1, pp.231-239, 2014.
DOI : 10.1016/j.biopsych.2005.03.013

D. T. Theodosis, J. J. Koksma, A. Trailin, S. L. Langle, R. Piet et al., Oxytocin and estrogen promote rapid formation of functional GABA synapses in the adult supraoptic nucleus, Molecular and Cellular Neuroscience, vol.31, issue.4, pp.785-794, 2006.
DOI : 10.1016/j.mcn.2006.01.006

E. Tierney, I. Bukelis, R. E. Thompson, K. Ahmed, A. Aneja et al., Abnormalities of cholesterol metabolism in autism spectrum disorders, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, vol.330, issue.6, pp.666-668, 2006.
DOI : 10.1002/ajmg.b.30368

E. Tierney, N. A. Nwokoro, and R. I. Kelley, Behavioral phenotype of RSH/Smith-Lemli-Opitz syndrome, Mental Retardation and Developmental Disabilities Research Reviews, vol.330, issue.2, pp.131-134, 2000.
DOI : 10.5014/ajot.51.7.530

E. Tierney, N. A. Nwokoro, F. D. Porter, L. S. Freund, J. K. Ghuman et al., Behavior phenotype in the RSH/Smith-Lemli-Opitz syndrome, American Journal of Medical Genetics, vol.5, issue.2, pp.191-200, 2001.
DOI : 10.2307/3001913

G. S. Tint, M. Irons, E. R. Elias, A. K. Batta, R. Frieden et al., Defective Cholesterol Biosynthesis Associated with the Smith-Lemli-Opitz Syndrome, New England Journal of Medicine, vol.330, issue.2, pp.107-113, 1994.
DOI : 10.1056/NEJM199401133300205

S. Tordjman, G. M. Anderson, P. A. Mcbride, M. E. Hertzig, M. E. Snow et al., Plasma ?-Endorphin, Adrenocorticotropin Hormone, and Cortisol in Autism, Journal of Child Psychology and Psychiatry, vol.97, issue.6, pp.705-715, 1997.
DOI : 10.1016/0024-3205(81)90385-4

S. Tordjman, P. Ferrari, V. Sulmont, M. Duyme, and P. Roubertoux, Androgenic Activity in Autism, American Journal of Psychiatry, vol.154, issue.11, pp.1626-1627, 1997.
DOI : 10.1176/ajp.154.11.1626-a

B. G. Travers, N. Adluru, C. Ennis, D. P. Tromp, D. Destiche et al., Diffusion Tensor Imaging in Autism Spectrum Disorder: A Review, Autism Research, vol.26, issue.Pt 9, pp.289-313, 2012.
DOI : 10.1176/appi.ajp.2011.11091447

I. I. Ucuz, O. B. Dursun, I. S. Esin, F. B. Ozgeris, N. Kurt et al., The relationship between Vitamin D, autistic spectrum disorders, and cognitive development: do glial cell line-derived neurotrophic factor and nerve growth factor play a role in this relationship?, International Journal of Developmental Disabilities, vol.162, issue.11, pp.222-230, 2014.
DOI : 10.1016/S0028-3908(99)00255-5

C. Utur and C. K. Gurkan, Serum vitamin D and folate levels in children with autism spectrum disorders, Research in Autism Spectrum Disorders, vol.8, pp.1641-1647, 2014.

S. Van-rijn, L. Stockmann, G. Van-buggenhout, C. Van-ravenswaaij-arts, and H. Swaab, Social cognition and underlying cognitive mechanisms in children with an extra X chromosome: a comparison with autism spectrum disorder, Genes, Brain and Behavior, vol.4, issue.Suppl 1, pp.459-467, 2014.
DOI : 10.1371/journal.pone.0005581

H. Waage-baudet, J. M. Lauder, D. B. Dehart, K. Kluckman, S. Hiller et al., Abnormal serotonergic development in a mouse model for the Smith???Lemli???Opitz syndrome: implications for autism, International Journal of Developmental Neuroscience, vol.21, issue.8, pp.451-459, 2003.
DOI : 10.1016/j.ijdevneu.2003.09.002

C. A. Wassif, P. Zhu, L. Kratz, P. A. Krakowiak, K. P. Battaile et al., Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith-Lemli-Opitz syndrome, Human Molecular Genetics, vol.10, issue.6, pp.555-564, 2001.
DOI : 10.1093/hmg/10.6.555

L. Waterhouse, D. Fein, and C. Modahl, Neurofunctional mechanisms in autism., Psychological Review, vol.103, issue.3, p.457, 1996.
DOI : 10.1037/0033-295X.103.3.457

O. Weisman, E. Agerbo, C. S. Carter, J. C. Harris, N. Uldbjerg et al., Oxytocin-augmented labor and risk for autism in males, Behavioural Brain Research, vol.284, pp.207-212, 2015.
DOI : 10.1016/j.bbr.2015.02.028

A. J. Whitehouse and . Kung, Commentary: Are we expecting too much from the extreme male brain theory of autism? A reflection on Kung et??al. (2016), Journal of Child Psychology and Psychiatry, vol.198, issue.12, pp.1463-1464, 2016.
DOI : 10.5694/mja12.11667

A. J. Whitehouse, B. J. Holt, M. Serralha, P. G. Holt, M. M. Kusel et al., Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive Development, PEDIATRICS, vol.129, issue.3, pp.485-493, 2012.
DOI : 10.1542/peds.2011-2644

A. J. Whitehouse, E. Mattes, M. T. Maybery, C. Dissanayake, M. Sawyer et al., Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study, Journal of Neurodevelopmental Disorders, vol.195, issue.1, p.25, 2012.
DOI : 10.1192/bjp.bp.108.053751

L. Wing, Sex ratios in early childhood autism and related conditions, Psychiatry Research, vol.5, issue.2, pp.129-137, 1981.
DOI : 10.1016/0165-1781(81)90043-3

M. Wiznitzer, Autism and Tuberous Sclerosis, Journal of Child Neurology, vol.48, issue.9, pp.675-679, 2004.
DOI : 10.1177/08830738020170111401

A. G. Woods, K. L. Wormwood, A. G. Wetie, J. P. Ryan, and C. C. Darie, Proteomics and cholesterol in autism, Autism, vol.3, issue.2, 2013.

K. L. Wormwood, E. J. Dupree, C. C. Darie, and A. G. Woods, Autism-open access, Health Perspect, vol.120, pp.944-951, 2014.

S. Wust, J. Wolf, D. H. Hellhammer, I. Federenko, N. Schommer et al., The cortisol awakening response?Normal values and confounds, Noise Health, vol.2, pp.79-88, 2000.

C. J. Yang, H. P. Tan, F. Y. Yang, C. L. Liu, B. Sang et al., The roles of cortisol and pro-inflammatory cytokines in assisting the diagnosis of autism spectrum disorder, Research in Autism Spectrum Disorders, vol.9, pp.174-181, 2015.
DOI : 10.1016/j.rasd.2014.10.012

K. Zinke, E. Fries, M. Kliegel, C. Kirschbaum, and L. Dettenborn, Children with high-functioning autism show a normal cortisol awakening response (CAR), Psychoneuroendocrinology, vol.35, issue.10, pp.1578-1582, 2010.
DOI : 10.1016/j.psyneuen.2010.03.009