Legionella and Legionnaires' Disease: 25 Years of Investigation, Clinical Microbiology Reviews, vol.15, issue.3, pp.506-532, 2002. ,
DOI : 10.1128/CMR.15.3.506-526.2002
Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae., Journal of Clinical Pathology, vol.33, issue.12, pp.1179-83, 1980. ,
DOI : 10.1136/jcp.33.12.1179
: an aquatic microbe goes astray, FEMS Microbiology Reviews, vol.26, issue.2, pp.149-62, 2002. ,
DOI : 10.1111/j.1574-6976.2002.tb00607.x
Disease: History and clinical findings, Legionella: Molecular Microbiology. 1, pp.1-19, 2008. ,
Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes, Journal of Clinical Investigation, vol.66, issue.3, pp.441-50, 1980. ,
DOI : 10.1172/JCI109874
to subvert host functions, Future Microbiology, vol.4, issue.6, pp.691-701, 2009. ,
DOI : 10.1371/journal.ppat.1000220
Expression of Legionella pneumophila virulence traits in response to growth conditions, Infect Immun, vol.66, issue.7, pp.3029-3063, 1998. ,
Differentiate to thrive: lessons from the Legionella pneumophila life cycle, Molecular Microbiology, vol.184, issue.1, pp.29-40, 2004. ,
DOI : 10.1128/jb.179.14.4639-4642.1997
Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila, Cellular Microbiology, vol.22, issue.8, pp.1228-1268, 2006. ,
DOI : 10.1093/nar/30.4.e15
Reduced expression of the global regulator protein CsrA in Legionella pneumophila affects virulence-associated regulators and growth in Acanthamoeba castellanii, International Journal of Medical Microbiology, vol.294, issue.1, pp.15-25, 2004. ,
DOI : 10.1016/j.ijmm.2003.12.003
Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication, Molecular Microbiology, vol.184, issue.2, pp.445-61, 2003. ,
DOI : 10.1128/jb.178.4.1012-1017.1996
Regulation of Bacterial Virulence by Csr (Rsm) Systems, Microbiology and Molecular Biology Reviews, vol.79, issue.2, pp.193-224, 2015. ,
DOI : 10.1128/MMBR.00052-14
RNA-binding proteins involved in post-transcriptional regulation in bacteria, Frontiers in Microbiology, vol.9, issue.e85626, pp.141-25784899, 2015. ,
DOI : 10.1016/S1097-2765(01)00437-3
differentiation in host macrophages, Molecular Microbiology, vol.5, issue.3, pp.640-58, 2008. ,
DOI : 10.1111/j.1365-2958.2008.06555.x
differentiation, Molecular Microbiology, vol.184, issue.5555, pp.200-219, 2010. ,
DOI : 10.1111/j.1365-2958.2010.07094.x
The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, posttranscriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors, Mol Microbiol, vol.72, issue.4, 2009. ,
Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence, RNA biology, vol.2012, issue.94, pp.503-522 ,
URL : https://hal.archives-ouvertes.fr/pasteur-01338351
Overexpresssion of a homologue of the regulator affects cell size, flagellation, and pigmentation, International Journal of Medical Microbiology, vol.291, issue.5, pp.353-60, 2001. ,
DOI : 10.1078/1438-4221-00141
orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit, Environmental Microbiology, vol.184, issue.2, pp.646-62, 2013. ,
DOI : 10.1128/JB.184.1.67-75.2002
URL : https://hal.archives-ouvertes.fr/pasteur-01336729
Synergistic Contribution of the Legionella pneumophila lqs Genes to Pathogen-Host Interactions, Journal of Bacteriology, vol.190, issue.22, pp.7532-7579, 2008. ,
DOI : 10.1128/JB.01002-08
The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila, Environmental Microbiology, vol.63, issue.5, pp.1243-59, 2010. ,
DOI : 10.4161/cib.7713
The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA, Cellular Microbiology, vol.63, issue.12, pp.2903-2923, 2007. ,
DOI : 10.1099/00221287-146-6-1345
The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii, Molecular Microbiology, vol.67, issue.5, pp.1508-1531, 2007. ,
DOI : 10.1128/IAI.71.7.3714-3723.2003
Identification of Legionella pneumophila Effectors Regulated by the LetAS-RsmYZ-CsrA Regulatory Cascade, Many of Which Modulate Vesicular Trafficking, Journal of Bacteriology, vol.196, issue.3, pp.681-92, 2014. ,
DOI : 10.1128/JB.01175-13
Regulatory interactions of Csr components: the RNA binding protein CsrA activates csrB transcription in Escherichia coli, J Bacteriol, vol.18320, issue.20, pp.6017-276017, 2001. ,
Identification and molecular characterization of csrA, a pleiotropic gene from Escherichia coli that affects glycogen biosynthesis, gluconeogenesis, cell size, and surface properties., Journal of Bacteriology, vol.175, issue.15, pp.4744-55, 1993. ,
DOI : 10.1128/jb.175.15.4744-4755.1993
Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA, Nature Structural & Molecular Biology, vol.177, issue.9, pp.807-820, 2007. ,
DOI : 10.1146/annurev.physchem.51.1.129
A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila, Molecular Microbiology, vol.273, issue.1, pp.107-125, 2002. ,
DOI : 10.1128/jb.166.1.187-193.1986
Control of Flagellar Gene Regulation in Legionella pneumophila and Its Relation to Growth Phase, Journal of Bacteriology, vol.192, issue.2, pp.446-55, 2009. ,
DOI : 10.1128/JB.00610-09
Mfold web server for nucleic acid folding and hybridization prediction, Nucleic Acids Research, vol.31, issue.13, pp.3406-3421, 2003. ,
DOI : 10.1093/nar/gkg595
Autoinducer Synthase LqsA Produces an ??-Hydroxyketone Signaling Molecule, Journal of Biological Chemistry, vol.53, issue.26, pp.18113-18136, 2008. ,
DOI : 10.1046/j.1365-2958.2003.03477.x
Protein LidA from Legionella is a Rab GTPase supereffector, Proceedings of the National Academy of Sciences, vol.60, issue.Pt 12 Pt 1, pp.17945-50, 2011. ,
DOI : 10.1107/S0907444904019158
A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system, Molecular Microbiology, vol.71, issue.4, pp.918-951, 2005. ,
DOI : 10.1091/mbc.10.2.435
The Legionella pneumophila effector protein, LegC7, alters yeast endosomal trafficking, ):e0116824. PubMed Central PMCID: PMCPMC4314205, p.25643265, 2015. ,
Rho-dependent terminators and transcription termination, Microbiology, vol.152, issue.9, pp.2515-2543, 2006. ,
DOI : 10.1099/mic.0.28982-0
URL : http://mic.microbiologyresearch.org/deliver/fulltext/micro/152/9/2515.pdf?itemId=/content/journal/micro/10.1099/mic.0.28982-0&mimeType=pdf&isFastTrackArticle=
RNA remodeling by bacterial global regulator CsrA promotes Rho-dependent transcription termination, Genes & Development, vol.28, issue.11, pp.1239-51, 2014. ,
DOI : 10.1101/gad.240192.114
URL : https://hal.archives-ouvertes.fr/hal-01178971
Amino acid requirements of Legionella pneumophila, J Clin Microbiol, vol.11, issue.3, pp.286-91, 1980. ,
Poly-3-hydroxybutyrate in Legionella pneumophila , an energy source for survival in low-nutrient environments, Appl Environ Microbiol, vol.65, issue.2, pp.822-829, 1999. ,
Staining and quantification of poly-3-hydroxybutyrate in Saccharomyces cerevisiae and Cupriavidus necator cell populations using automated flow cytometry, Cytometry A, vol.69, issue.1, pp.27-35, 2006. ,
Thiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease models, FEBS Journal, vol.40, issue.24, pp.6412-6454, 2013. ,
DOI : 10.1093/nar/gkr998
The THI-box Riboswitch, or How RNA Binds Thiamin Pyrophosphate, Structure, vol.15, issue.3, pp.259-65, 2007. ,
DOI : 10.1016/j.str.2007.02.001
Chemically defined medium for Legionella pneumophila growth, J Clin Microbiol, vol.13, pp.115-124, 1981. ,
Dual Posttranscriptional Regulation via a Cofactor-Responsive mRNA Leader, Journal of Molecular Biology, vol.425, issue.19, pp.3662-77, 2013. ,
DOI : 10.1016/j.jmb.2012.12.010
???Ride on the ferrous wheel??? ??? The cycle of iron in macrophages in health and disease, Immunobiology, vol.220, issue.2, pp.280-94, 2015. ,
DOI : 10.1016/j.imbio.2014.09.010
: new pathways for siderophore uptake and ferric iron reduction, Future Microbiology, vol.2, issue.6, pp.841-51, 2015. ,
DOI : 10.1007/s10534-009-9219-2
Interplay between iron homeostasis and virulence: Fur and RyhB as major regulators of bacterial pathogenicity, Veterinary Microbiology, vol.179, issue.1-2, pp.2-14, 2015. ,
DOI : 10.1016/j.vetmic.2015.03.024
URL : https://hal.archives-ouvertes.fr/pasteur-01352636
virulence against amoebae and macrophages, Environmental Microbiology, vol.81, issue.Part 6, pp.1338-50, 2015. ,
DOI : 10.1128/IAI.00858-13
URL : https://hal.archives-ouvertes.fr/pasteur-01327258
The product of the pleiotropic Escherichia coli gene csrA modulates glycogen biosynthesis via effects on mRNA stability., Journal of Bacteriology, vol.177, issue.10, pp.2663-72, 1995. ,
DOI : 10.1128/jb.177.10.2663-2672.1995
mRNA from RNase E-mediated cleavage, Molecular Microbiology, vol.31, issue.4, pp.851-66, 2013. ,
DOI : 10.1093/nar/gkg595
??S Controls Multiple Pathways Associated with Intracellular Multiplication of Legionella pneumophila, Journal of Bacteriology, vol.191, issue.8, pp.2461-73, 2009. ,
DOI : 10.1128/JB.01578-08
Complex regulation of the global regulatory gene csrA: CsrA-mediated translational repression, transcription from five promoters by E??70 and E??S, and indirect transcriptional activation by CsrA, Molecular Microbiology, vol.64, issue.3, pp.689-704, 2011. ,
DOI : 10.1111/j.1365-2958.2007.05765.x
Circuitry linking the Csr and stringent response global regulatory systems, Molecular Microbiology, vol.178, issue.6, pp.1561-80, 2011. ,
DOI : 10.1128/jb.178.4.1012-1017.1996
CsrA modulates luxR transcript levels in Vibrio fischeri, FEMS Microbiology Letters, vol.329, issue.1, pp.28-35, 2012. ,
DOI : 10.1111/j.1574-6968.2012.02499.x
The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication, Cellular Microbiology, vol.202, issue.9, pp.1272-91, 2010. ,
DOI : 10.1016/j.bbamcr.2004.01.006
Co-immunoprecipitation: Protein???RNA and Protein???DNA Interaction, Methods Mol Biol, vol.954, pp.583-93, 2013. ,
DOI : 10.1007/978-1-62703-161-5_36
URL : https://hal.archives-ouvertes.fr/pasteur-01333974
cDNA Library Construction for Next-Generation Sequencing to Determine the Transcriptional Landscape of Legionella pneumophila, Methods Mol Biol, vol.954, pp.555-66, 2013. ,
DOI : 10.1007/978-1-62703-161-5_34
URL : https://hal.archives-ouvertes.fr/pasteur-01334075
BEDTools: a flexible suite of utilities for comparing genomic features, Bioinformatics, vol.26, issue.6, pp.841-843, 2010. ,
DOI : 10.1093/bioinformatics/btq033
Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data, Bioinformatics, vol.28, issue.4, pp.464-473, 2012. ,
DOI : 10.1093/bioinformatics/btr703
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository, Nucleic Acids Research, vol.30, issue.1, pp.207-217, 2002. ,
DOI : 10.1093/nar/30.1.207
Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA, Molecular Microbiology, vol.171, issue.23, pp.1613-1638, 2003. ,
DOI : 10.1128/jb.171.5.2795-2802.1989
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation, Nucleic Acids Research, vol.30, issue.4, pp.15-11842121, 2002. ,
DOI : 10.1093/nar/30.4.e15
VarMixt: efficient variance modelling for the differential analysis of replicated gene expression data, Bioinformatics, vol.21, issue.4, pp.502-510, 2005. ,
DOI : 10.1093/bioinformatics/bti023
URL : https://hal.archives-ouvertes.fr/hal-00126119
Identifying differentially expressed genes using false discovery rate controlling procedures, Bioinformatics, vol.19, issue.3, pp.368-75, 2003. ,
DOI : 10.1093/bioinformatics/btf877
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification, Nature Biotechnology, vol.7, issue.12, pp.1367-72, 2008. ,
DOI : 10.1038/nprot.2007.261
Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment, Journal of Proteome Research, vol.10, issue.4, pp.1794-805, 2011. ,
DOI : 10.1021/pr101065j
Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ, Molecular & Cellular Proteomics, vol.10, issue.9, pp.2513-2539, 2014. ,
DOI : 10.1074/mcp.M111.011015
2016 update of the PRIDE database and its related tools, Nucleic Acids Research, vol.44, issue.D1, pp.447-56, 2016. ,
DOI : 10.1093/nar/gkv1145