Detection of interferon alpha protein reveals differential levels and cellular sources in disease.

Mathieu P. Rodero (1) , Jérémie Decalf (2) , Vincent Bondet (2) , David Hunt (3, 4) , Gillian I. Rice (5) , Scott Werneke (2) , Sarah L. Mcglasson (4, 3) , Marie Alyanakian (6) , Brigitte Bader-Meunier (6, 7) , Christine Barnerias (8) , Nathalia Bellon (9) , Alexandre Belot (10, 11) , Christine Bodemer (9, 7) , Tracy A Briggs (12, 5) , Isabelle Desguerre (8) , Marie Frémond (1) , Marie Hully (8) , Arn M J M van den Maagdenberg (13, 14) , Isabelle Melki (1, 6, 15) , Isabelle Meyts (16, 17) , Lucile Musset (18) , Nadine Pelzer (13) , Pierre Quartier (6) , Gisela M Terwindt (13) , Joanna Wardlaw (3) , Stewart Wiseman (3) , Frédéric Rieux-Laucat (7) , Yoann Rose (1) , Bénédicte Neven (6) , Christina Hertel (19) , Adrian Hayday (20, 21) , Matthew L. Albert (2) , Flore Rozenberg (22, 23) , Yanick J Crow (1, 24) , Darragh Duffy (2)

1 Equipe Inserm U1163 - Laboratory of neurogenetics and neuroinflammation
2 Immunobiologie des Cellules dendritiques
3 CCBS - Centre For Clinical Brain Sciences - Neuroimaging Sciences [Edinburgh, U.K.]
4 Medical Research Council (MRC) Human Genetics Unit [Edinburgh]
5 MCGM - Manchester Centre for Genomic Medicine [Manchester, UK]
6 Service d'immuno-hématologie pédiatrique [CHU Necker]
7 IMAGINE - U1163 - Imagine - Institut des maladies génétiques
8 Service de neurologie pédiatrique [CHU Necker]
9 Service de dermatologie [CHU Necker]
10 Réponse immunitaire innée dans les maladies infectieuses et auto-immunes – Innate immunity in infectious and autoimmune diseases
11 HCL - Hospices Civils de Lyon
12 Division of Evolution and Genomic Science [Manchester]
13 Department of Neurology
14 Departments of Human Genetics & Neurology
15 General Paediatrics, Infectious Disease and Internal Medicine Department [Robert-Debré]
16 Department of Microbiology and Immunology
17 Pediatric Immunodeficiencies
18 Service d'Immunologie [CHU Pitié-Salpétrière]
19 ImmunoQure AG
20 Peter Gorer Department of Immunobiology
21 The Francis Crick Institute [London]
22 UPD5 - Université Paris Descartes - Paris 5
23 Service de Virologie [CHU Cochin]
24 Service de Génétique Médicale [CHU Necker]

Domains: Life Sciences [q-bio]; Immunology

Mathieu P. Rodero, Jérémie Decalf, Vincent Bondet, David Hunt, Gillian I. Rice, et al.. Detection of interferon alpha protein reveals differential levels and cellular sources in disease.. Journal of Experimental Medicine, 2017, 214 (5), pp.1547-1555. ⟨10.1084/jem.20161451⟩. ⟨pasteur-01534181⟩