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Protozoan Parasites and Type I IFNs.

Abstract : For many years, the role of interferon (IFN)-I has been characterized primarily in the context of viral infections. However, regulatory functions mediated by IFN-I have also been described against bacterial infections and in tumor immunology. Only recently, the interest in understanding the immune functions mediated by IFN-I has dramatically increased in the field of protozoan infections. In this review, we discuss the discrete role of IFN-I in the immune response against major protozoan infections: Plasmodium, Leishmania, Trypanosoma, and Toxoplasma.
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Sasha Silva-Barrios, Simona Stäger. Protozoan Parasites and Type I IFNs.. Frontiers in Immunology, Frontiers, 2017, 8, pp.Article 14. ⟨10.3389/fimmu.2017.00014⟩. ⟨pasteur-01533834⟩

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