Phylogenetic structure of European Salmonella Enteritidis outbreak correlates with national and international egg distribution network.

Abstract : Outbreaks of Salmonella Enteritidis have long been associated with contaminated poultry and eggs. In the summer of 2014 a large multi-national outbreak of Salmonella Enteritidis phage type 14b occurred with over 350 cases reported in the United Kingdom, Germany, Austria, France and Luxembourg. Egg supply network investigation and microbiological sampling identified the source to be a Bavarian egg producer. As part of the international investigation into the outbreak, over 400 isolates were sequenced including isolates from cases, implicated UK premises and eggs from the suspected source producer. We were able to show a clear statistical correlation between the topology of the UK egg distribution network and the phylogenetic network of outbreak isolates. This correlation can most plausibly be explained by different parts of the egg distribution network being supplied by eggs solely from independent premises of the Bavarian egg producer (Company X). Microbiological sampling from the source premises, traceback information and information on the interventions carried out at the egg production premises all supported this conclusion. The level of insight into the outbreak epidemiology provided by whole-genome sequencing (WGS) would not have been possible using traditional microbial typing methods.
Type de document :
Article dans une revue
Microbial Genomics, Society for General Microbiology, 2016, 2 (8), pp.e000070. 〈10.1099/mgen.0.000070〉
Liste complète des métadonnées

Littérature citée [34 références]  Voir  Masquer  Télécharger

https://hal-pasteur.archives-ouvertes.fr/pasteur-01524578
Contributeur : Marie Lemesle <>
Soumis le : jeudi 18 mai 2017 - 14:18:44
Dernière modification le : mercredi 21 février 2018 - 17:44:03

Fichier

Phylogenetic structure .pdf
Publication financée par une institution

Licence


Distributed under a Creative Commons Paternité - Pas d'utilisation commerciale 4.0 International License

Identifiants

Collections

Citation

Tim Dallman, Thomas Inns, Thibaut Jombart, Philip Ashton, Nicolas Loman, et al.. Phylogenetic structure of European Salmonella Enteritidis outbreak correlates with national and international egg distribution network.. Microbial Genomics, Society for General Microbiology, 2016, 2 (8), pp.e000070. 〈10.1099/mgen.0.000070〉. 〈pasteur-01524578〉

Partager

Métriques

Consultations de la notice

86

Téléchargements de fichiers

111