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Journal articles
Candida albicans is not always the preferential yeast colonizing humans: a study in Wayampi Amerindians.
Abstract : In industrialized countries Candida albicans is considered the predominant commensal yeast of the human intestine, with approximately 40% prevalence in healthy adults. We discovered a highly original colonization pattern that challenges this current perception by studying in a 4- year interval a cohort of 151 Amerindians living in a remote community (French Guiana), and animals from their environment. The prevalence of C. albicans was persistently low (3% and 7% of yeast carriers). By contrast, Candida krusei and Saccharomyces cerevisiae were detected in over 30% of carriers. We showed that C. krusei and S. cerevisiae carriage was of food or environmental origin, whereas C. albicans carriage was associated with specific risk factors (being female and living in a crowded household). We also showed using whole-genome sequence comparison that C. albicans strains can persist in the intestinal tract of a healthy individual over a 4-year period.
Cited literature [48 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01522841
Contributor : Christelle Lenormand <>
Submitted on : Monday, May 15, 2017 - 4:07:09 PM
Last modification on : Wednesday, October 14, 2020 - 3:47:06 AM
Long-term archiving on: : Thursday, August 17, 2017 - 12:48:57 AM
Contributor : Christelle Lenormand <>
Submitted on : Monday, May 15, 2017 - 4:07:09 PM
Last modification on : Wednesday, October 14, 2020 - 3:47:06 AM
Long-term archiving on: : Thursday, August 17, 2017 - 12:48:57 AM