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Genetic diversity among Candida albicans isolates associated with vertical transmission in preterm triplets.

Gautier Hoarau 1 Marie-Elisabeth Bougnoux 2, 3 Antoine Fily 4, 1 Nadine François 1 Séverine Loridant 1 Samir Jawhara 1 Christophe d'Enfert 3 Daniel Poulain 1 Boualem Sendid 1, *
* Corresponding author
1 CHRU Lille - Centre Hospitalier Régional Universitaire [Lille]
2 Unité de Parasitologie-Mycologie, Service de Microbiologie [Hôpital Necker-Enfants-Malades, Paris]
3 Biologie et Pathogénicité fongiques
4 Service de Médecine Néonatale
Abstract : We report a case of congenital candidiasis in triplets, in the context of premature labor at 25 weeks gestation, without symptomatic vaginitis or chorioamnionitis. All three infants died as a result of prematurity, aggravated by systemic candidiasis. Multi-locus sequence typing confirmed vertical transmission of Candida albicans from the mother to the triplets and revealed a slight diversity among the strains isolated from the neonates.
Keywords : Multi-locus sequence typing Vertical transmission Candida albicans Congenital candidiasis
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https://hal-pasteur.archives-ouvertes.fr/pasteur-01518493
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Submitted on : Thursday, May 4, 2017 - 5:29:53 PM
Last modification on : Wednesday, May 27, 2020 - 5:56:25 AM

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Gautier Hoarau, Marie-Elisabeth Bougnoux, Antoine Fily, Nadine François, Séverine Loridant, et al.. Genetic diversity among Candida albicans isolates associated with vertical transmission in preterm triplets.. Mycopathologia, Springer Verlag, 2014, 178 (3-4), pp.285-90. ⟨10.1007/s11046-014-9803-z⟩. ⟨pasteur-01518493⟩

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