 |
Journal articles
The Diverse Family of Arp2/3 Complexes.
Abstract : The Arp2/3 complex has so far been considered to be a single seven-subunit protein complex required for actin nucleation and actin filament polymerization in diverse critical cellular functions including phagocytosis, vesicular trafficking and lamellipodia extension. The Arp2/3 complex is also exploited by bacterial pathogens and viruses during cellular infectious processes. Recent studies suggest that some subunits of the complex are dispensable in specific cellular contexts, pointing to the existence of alternative 'hybrid Arp2/3 complexes' containing other components such as vinculin or α-actinin, as well as different isoforms or phosphorylation variants of canonical Arp2/3 subunits. Therefore, this diversity should be now considered when assigning specific Arp2/3 assemblies to different actin-dependent cellular processes.
https://hal-pasteur.archives-ouvertes.fr/pasteur-01457856
Contributor : Javier Pizarro-Cerda Connect in order to contact the contributor
Submitted on : Monday, February 6, 2017 - 3:51:52 PM
Last modification on : Wednesday, November 3, 2021 - 9:16:36 AM
Long-term archiving on: : Sunday, May 7, 2017 - 2:40:39 PM
Contributor : Javier Pizarro-Cerda Connect in order to contact the contributor
Submitted on : Monday, February 6, 2017 - 3:51:52 PM
Last modification on : Wednesday, November 3, 2021 - 9:16:36 AM
Long-term archiving on: : Sunday, May 7, 2017 - 2:40:39 PM
Files
Pizarro-Cerda et al. Main Manu...
Files produced by the author(s)
- Figure 1.pdf Files produced by the author(s)
- Outstanding Question Box.pdf Files produced by the author(s)
- Table 1.pdf Files produced by the author(s)
- Trends Box.pdf Files produced by the author(s)
Licence
Distributed under a Creative Commons Attribution - NonCommercial - ShareAlike 4.0 International License