Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study.

Van-Mai Cao-Lormeau (1) , Alexandre Blake (2) , Sandrine Mons (3) , Stéphane Lastère (3) , Claudine Roche (1) , Jessica Vanhomwegen (4, 5) , Timothée Dub (2) , Laure Baudouin (3) , Anita Teissier (2) , Philippe Larre (3) , Anne-Laure Vial (6) , Christophe Decam (7) , Valérie Choumet (4) , Susan K Halstead (8) , Hugh J Willison (8) , Lucile Musset (9) , Jean Manuguerra (4, 5) , Philippe Desprès (10) , Emmanuel Fournier (9) , Henri-Pierre Mallet (11) , Didier Musso (1) , Arnaud Fontanet (12, 2, 13) , Jean Neil (9) , Frédéric Ghawché (3)

1 ILM - Institut Louis Malardé [Papeete]
2 Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology
3 Centre Hospitalier de Polynésie Française
4 ERI - Environnement et Risques infectieux - Environment and Infectious Risks
5 CIBU - Cellule d'Intervention Biologique d'Urgence - Laboratory for Urgent Response to Biological Threats
6 Direction de la Santé - Bureau de veille sanitaire [Papeete]
7 Service de santé des forces armées [Papeete]
8 University of Glasgow
9 CHU Pitié-Salpêtrière [AP-HP]
10 PIMIT - Processus Infectieux en Milieu Insulaire Tropical
11 Direction de la Santé de la Polynésie Française
12 CGH - Center for Global Health Research and Education - Centre pour la Recherche et la Formation en Santé Mondiale
13 CNAM - Conservatoire National des Arts et Métiers [CNAM]

Between October, 2013, and April, 2014, French Polynesia experienced the largest Zika virus outbreak ever described at that time. During the same period, an increase in Guillain-Barré syndrome was reported, suggesting a possible association between Zika virus and Guillain-Barré syndrome. We aimed to assess the role of Zika virus and dengue virus infection in developing Guillain-Barré syndrome.

Domains: Life Sciences [q-bio]; Santé publique et épidémiologie; Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Van-Mai Cao-Lormeau, Alexandre Blake, Sandrine Mons, Stéphane Lastère, Claudine Roche, et al.. Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study.. The Lancet, 2016, 387 (10027), pp.1531-1539. ⟨10.1016/S0140-6736(16)00562-6⟩. ⟨pasteur-01453407⟩