 |
Journal articles
Vibrio cholerae triggers SOS and mutagenesis in response to a wide range of antibiotics: a route towards multiresistance.
Abstract : Antibiotic resistance development has been linked to the bacterial SOS stress response. In Escherichia coli, fluoroquinolones are known to induce SOS, whereas other antibiotics, such as aminoglycosides, tetracycline, and chloramphenicol, do not. Here we address whether various antibiotics induce SOS in Vibrio cholerae. Reporter green fluorescent protein (GFP) fusions were used to measure the response of SOS-regulated promoters to subinhibitory concentrations of antibiotics. We show that unlike the situation with E. coli, all these antibiotics induce SOS in V. cholerae.
https://hal-pasteur.archives-ouvertes.fr/pasteur-01423615
Contributor : Isabelle Hoffmann <>
Submitted on : Friday, December 30, 2016 - 4:19:28 PM
Last modification on : Tuesday, December 8, 2020 - 10:07:54 AM
Long-term archiving on: : Tuesday, March 21, 2017 - 5:08:02 AM
Contributor : Isabelle Hoffmann <>
Submitted on : Friday, December 30, 2016 - 4:19:28 PM
Last modification on : Tuesday, December 8, 2020 - 10:07:54 AM
Long-term archiving on: : Tuesday, March 21, 2017 - 5:08:02 AM
File
zac2438.pdf
Publication funded by an institution
Licence
Distributed under a Creative Commons Attribution 4.0 International License