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Design of a Specific Colonic Mucus Marker Using a Human Commensal Bacterium Cell Surface Domain

Abstract : Background: Imaging colonic mucus on living cells, tissues, and organs is required for live microscopy. Results: We have identified, synthesized, and validated a new human colonic mucus bacterial marker (MUB 70). Conclusion: This non-toxic marker is used to image the secreted colonic mucus. Significance: Beyond imaging applications, Cy5-MUB 70 might be used for diagnostic and prognosis applications on colonic mucinous carcinoma.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-01423132
Contributor : Françoise Baleux <>
Submitted on : Wednesday, December 28, 2016 - 3:30:27 PM
Last modification on : Wednesday, September 23, 2020 - 4:31:42 AM
Long-term archiving on: : Tuesday, March 21, 2017 - 5:54:44 AM

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J. Biol. Chem.-2012-Coïc-159...
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Yves-Marie Coïc, Francoise Baleux, Ömer Poyraz, Roman Thibeaux, Elisabeth Labruyere, et al.. Design of a Specific Colonic Mucus Marker Using a Human Commensal Bacterium Cell Surface Domain. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, ⟨10.1074/jbc.M111.310003⟩. ⟨pasteur-01423132⟩

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