Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS), Science, vol.220, pp.868-871, 1983. ,
Inhibiting sexual transmission of HIV-1 infection, Nature reviews. Microbiology, vol.1, pp.25-34, 2003. ,
DOI : 10.1038/nrmicro729
Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annual review of medicine 62, pp.127-139, 2011. ,
DOI : 10.1146/annurev-med-080709-124959
Entry of viruses through the epithelial barrier: pathogenic trickery, Nature reviews. Molecular cell biology, vol.4, pp.57-68, 2003. ,
DOI : 10.1038/nrm1005
HIV and mucosal barrier interactions: consequences for transmission and pathogenesis, Current opinion in immunology, vol.36, pp.22-30, 2015. ,
DOI : 10.1016/j.coi.2015.06.004
HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV, Journal of translational medicine, vol.9, issue.1, 2011. ,
Human immunodeficiency virus and heparan sulfate: from attachment to entry inhibition, Frontiers in immunology, vol.4, 2013. ,
DOI : 10.3389/fimmu.2013.00385
URL : https://hal.archives-ouvertes.fr/hal-00924124
HIV sexual transmission and microbicides, Reviews in medical virology, vol.21, pp.110-133, 2011. ,
, Scientific RepoRts |, vol.6
Preventing mucosal HIV transmission with topical microbicides: challenges and opportunities, Antiviral research, vol.88, 2010. ,
DOI : 10.1016/j.antiviral.2010.09.011
URL : http://europepmc.org/articles/pmc3032991?pdf=render
Microbicides for the prevention of sexually transmitted HIV infection. Expert review of anti-infective therapy 11, pp.13-23, 2013. ,
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission. Annual review of medicine 59, pp.455-471, 2008. ,
DOI : 10.1146/annurev.med.59.061206.112737
The rise and fall of polyanionic inhibitors of the human immunodeficiency virus type 1, Antiviral research, vol.90, pp.168-182, 2011. ,
Non-specific microbicide product development: then and now, Current HIV research, vol.10, pp.9-18, 2012. ,
Polyanionic candidate microbicides accelerate the formation of semen-derived amyloid fibrils to enhance HIV-1 infection, PloS one, vol.8, p.59777, 2013. ,
Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission, The New England journal of medicine, vol.359, pp.463-472, 2008. ,
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques, Mucosal immunology, vol.7, pp.46-56, 2014. ,
Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor, Science translational medicine, vol.6, pp.243-288, 2014. ,
Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women, The New England journal of medicine, 2016. ,
Safety of tenofovir gel, a vaginal microbicide, South African women: results of the CAPRISA 004 Trial, vol.18, pp.301-310, 2013. ,
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques, The Journal of antimicrobial chemotherapy, vol.68, pp.678-683, 2013. ,
Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: A DoubleBlind Randomized Trial, Journal of acquired immune deficiency syndromes, vol.70, pp.242-249, 1999. ,
A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry, Nat Chem Biol, vol.5, pp.743-748, 2009. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00415325
A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti-HIV-1 activity independently of coreceptor usage, Chemistry & biology, vol.19, pp.131-139, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00664771
The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site, J Biol Chem, vol.283, pp.15193-15200, 2008. ,
Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site, J Biol Chem, vol.280, pp.21353-21357, 2005. ,
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry, Cell, vol.96, pp.667-676, 1999. ,
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection, Proceedings of the National Academy of Sciences of the United States of America 105, pp.7552-7557, 2008. ,
Progesterone implants enhance SIV vaginal transmission and early virus load, Nature medicine, vol.2, pp.1084-1089, 1996. ,
Influence of the MHC genotype on the progression of experimental SIV infection in the Mauritian cynomolgus macaque, Immunogenetics, vol.63, pp.267-274, 2011. ,
MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques, PLoS pathogens, vol.8, p.1003071, 2012. ,
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5, Science, vol.306, pp.485-487, 2004. ,
Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models, AIDS research and human retroviruses, vol.20, pp.11-18, 2004. ,
Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor, The Journal of infectious diseases, vol.202, pp.739-744, 2010. ,
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion, Nature, vol.438, pp.99-102, 2005. ,
MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency, Retrovirology, vol.9, p.36, 2012. ,
Interfacial cavity filling to optimize CD4-mimetic miniprotein interactions with HIV-1 surface glycoprotein, Journal of medicinal chemistry, vol.56, pp.5033-5047, 2013. ,
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117, Nature, vol.522, pp.487-491, 2015. ,
Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission, The Journal of antimicrobial chemotherapy, vol.68, pp.2038-2047, 2013. ,
Human immunodeficiency virus type 1 resistance or cross-resistance to nonnucleoside reverse transcriptase inhibitors currently under development as microbicides, Antimicrobial agents and chemotherapy, vol.55, pp.1403-1413, 2011. ,
HIV gp120 H375 is unique to HIV-1 subtype CRF01_AE and confers strong resistance to the entry inhibitor BMS-599793, a candidate microbicide drug, Antimicrobial agents and chemotherapy, vol.56, pp.4257-4267, 2012. ,
HIV-infected T cells are migratory vehicles for viral dissemination, Nature, vol.490, pp.283-287, 2012. ,
DOI : 10.1038/nature11398
URL : http://europepmc.org/articles/pmc3470742?pdf=render
The direct passage of animal viruses between cells, Current opinion in virology, vol.1, pp.396-402, 2011. ,
Inefficient human immunodeficiency virus replication in mobile lymphocytes, Journal of virology, vol.81, pp.1000-1012, 2007. ,
DOI : 10.1128/jvi.01629-06
URL : https://hal.archives-ouvertes.fr/pasteur-00292736
Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission, The Journal of experimental medicine, vol.210, pp.2813-2821, 2013. ,
DOI : 10.1084/jem.20131244
URL : https://hal.archives-ouvertes.fr/pasteur-01108608
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptorbinding site on gp120, Proceedings of the National Academy of Sciences of the United States of America, vol.101, pp.2706-2711, 2004. ,
Characterization of the rheological, mucoadhesive, and drug release properties of highly structured gel platforms for intravaginal drug delivery, Biomacromolecules, vol.10, pp.2427-2435, 2009. ,
, Scientific RepoRts |, vol.6
Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge, The Journal of infectious diseases, vol.199, pp.1525-1527, 2009. ,
DOI : 10.1086/598685
URL : https://academic.oup.com/jid/article-pdf/199/10/1525/18056564/199-10-1525.pdf
Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains, Virology, vol.475, pp.187-203, 2015. ,
Reduced production of sulfated glycosaminoglycans occurs in Zambian children with kwashiorkor but not marasmus, The American journal of clinical nutrition, vol.89, pp.592-600, 2009. ,
Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells, The Journal of experimental medicine, vol.206, pp.2717-2733, 2009. ,
DOI : 10.1083/jcb1873oia5
Mechanisms of enhanced HIV spread through T-cell virological synapses, Immunological reviews, vol.251, pp.113-124, 2013. ,
DOI : 10.1111/imr.12022
Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies, PLoS pathogens, vol.8, p.1002634, 2012. ,
DOI : 10.1371/journal.ppat.1002634
URL : https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002634&type=printable
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy, Nature, vol.477, pp.95-98, 2011. ,
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys, Nature, vol.503, pp.224-228, 2013. ,
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques, The Journal of experimental medicine, vol.211, pp.2061-2074, 2014. ,
An HIV gp120-CD4 Immunogen Does Not Elicit Autoimmune Antibody Responses in Cynomolgus Macaques, Clinical and vaccine immunology : CVI, vol.23, pp.618-627, 2016. ,
Mucosal transmission and induction of simian AIDS by CCR5-specific simian/human immunodeficiency virus SHIV(SF162P3), Journal of virology, vol.75, 1990. ,
Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs, Science, vol.284, pp.816-819, 1999. ,
DOI : 10.1126/science.284.5415.816
Prevention of vaginal simian immunodeficiency virus transmission in macaques by postexposure prophylaxis with zidovudine, lamivudine and indinavir, AIDS, vol.23, pp.447-454, 2009. ,
Dynamics of viral replication in blood and lymphoid tissues during SIVmac251 infection of macaques, Retrovirology, vol.6, 2009. ,
Innate sensing of HIV-infected cells, PLoS pathogens, vol.7, p.1001284, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00590930
Elimination of HIV-1-infected cells by broadly neutralizing antibodies, Nature communications, vol.7, p.10844, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01372390