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Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution.

Abstract : The fine three-dimensional structure of the nucleosomal fiber has remained elusive to genome-wide chromosome conformation capture (3C) approaches. A new study mapping contacts at the single nucleosome level (Micro-C) reveals topological interacting domains along budding yeast chromosomes. These domains encompass one to five consecutive genes and are delimited by highly active promoters.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-01420328
Contributor : Romain Koszul <>
Submitted on : Tuesday, December 20, 2016 - 2:25:28 PM
Last modification on : Tuesday, June 16, 2020 - 11:38:02 PM
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Julien Mozziconacci, Romain Koszul. Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution.. Genome Biology, BioMed Central, 2015, 16 (1), pp.169. ⟨10.1186/s13059-015-0744-8⟩. ⟨pasteur-01420328⟩

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