XLF Interacts with the XRCC4-DNA Ligase IV Complex to Promote DNA Nonhomologous End-Joining, Cell, vol.124, issue.2, pp.301-313, 2006. ,
DOI : 10.1016/j.cell.2005.12.031
A high-throughput in vivo micronucleus assay for genome instability screening in mice, Nature Protocols, vol.163, issue.1, pp.205-215, 2015. ,
DOI : 10.2527/jas.2006-449
Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia, Cell, vol.86, issue.1, pp.159-171, 1996. ,
DOI : 10.1016/S0092-8674(00)80086-0
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice, Current Biology, vol.8, issue.25, pp.1395-1398, 1998. ,
DOI : 10.1016/S0960-9822(98)00021-9
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2, The EMBO Journal, vol.59, issue.21, pp.3413-3427, 2009. ,
DOI : 10.1038/ncb1446
Cernunnos, a Novel Nonhomologous End-Joining Factor, Is Mutated in Human Immunodeficiency with Microcephaly, Cell, vol.124, issue.2, pp.287-299, 2006. ,
DOI : 10.1016/j.cell.2005.12.030
XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair, Cell Death and Differentiation, vol.27, issue.6, pp.890-897, 2015. ,
DOI : 10.1371/journal.pone.0007016
Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV, Nature, vol.396, pp.173-177, 1998. ,
A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis, Cell, vol.95, issue.7, pp.891-902, 1998. ,
DOI : 10.1016/S0092-8674(00)81714-6
One ring to bring them all???The role of Ku in mammalian non-homologous end joining, DNA Repair, vol.17, pp.30-38, 2014. ,
DOI : 10.1016/j.dnarep.2014.02.019
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice, Proceedings of the National Academy of Sciences, vol.97, issue.6, pp.2668-2673, 2000. ,
DOI : 10.1073/pnas.97.6.2668
The DNA-damage response in human biology and disease, Nature, vol.37, issue.7267, pp.1071-1078, 2009. ,
DOI : 10.1038/nature08467
Quantitative Live Cell Imaging Reveals a Gradual Shift between DNA Repair Mechanisms and a Maximal Use of HR in Mid S Phase, Molecular Cell, vol.47, issue.2, pp.320-329, 2012. ,
DOI : 10.1016/j.molcel.2012.05.052
The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants, DNA Repair, vol.1, issue.12, pp.1017-1026, 2002. ,
DOI : 10.1016/S1568-7864(02)00151-9
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line, Proceedings of the National Academy of Sciences, vol.113, issue.38, pp.10619-10624, 2016. ,
DOI : 10.1073/pnas.1611882113
RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair, Nature Communications, vol.3, p.10529, 2016. ,
DOI : 10.1093/bioinformatics/btr670
URL : https://hal.archives-ouvertes.fr/pasteur-01295756
Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination, Cell Reports, vol.16, issue.11, pp.2967-2979, 2016. ,
DOI : 10.1016/j.celrep.2016.08.069
URL : https://hal.archives-ouvertes.fr/pasteur-01369781
Lymphocyte-Specific Compensation for XLF/Cernunnos End-Joining Functions in V(D)J Recombination, Molecular Cell, vol.31, issue.5, pp.631-640, 2008. ,
DOI : 10.1016/j.molcel.2008.07.017
URL : http://doi.org/10.1016/j.molcel.2008.07.017
Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development, Proceedings of the National Academy of Sciences, vol.109, issue.10, pp.3903-3908, 2012. ,
DOI : 10.1073/pnas.1120160109
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination, Nature, vol.382, issue.6591, pp.551-555, 1996. ,
DOI : 10.1038/382551a0
The spatial organization of non-homologous end joining: From bridging to end joining, DNA Repair, vol.17, pp.98-109, 2014. ,
DOI : 10.1016/j.dnarep.2014.02.010
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair, Science, vol.347, issue.6218, pp.185-188, 2015. ,
DOI : 10.1126/science.1261971
Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair, Proceedings of the National Academy of Sciences, vol.109, issue.7, pp.2455-2460, 2012. ,
DOI : 10.1073/pnas.1121458109
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289340
Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo, The Journal of Experimental Medicine, vol.59, issue.6, pp.921-929, 1997. ,
DOI : 10.1084/jem.175.6.1677
The clinical impact of deficiency in DNA non-homologous end-joining, DNA Repair, vol.16, pp.84-96, 2014. ,
DOI : 10.1016/j.dnarep.2014.02.011
Biology and Applications of CRISPR Systems: Harnessing Nature???s Toolbox for Genome Engineering, Cell, vol.164, issue.1-2, pp.29-44, 2016. ,
DOI : 10.1016/j.cell.2015.12.035
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway, Nature Communications, vol.6, p.6233, 2015. ,
DOI : 10.1038/emboj.2012.304
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks, Nature, vol.296, issue.7329, pp.250-254, 2011. ,
DOI : 10.1038/nature09604
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058373
Ku86-Deficient Mice Exhibit Severe Combined Immunodeficiency and Defective Processing of V(D)J Recombination Intermediates, Cell, vol.86, issue.3, pp.379-389, 1996. ,
DOI : 10.1016/S0092-8674(00)80111-7