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Journal articles
Combined medico-surgical strategy for invasive sino-orbito-cerebral breakthrough fungal infection with Hormographiella aspergillata in an acute leukaemia patient
Abstract : Hormographiella aspergillata is a rare causative agent of invasive filamentous breakthrough infection, mostly arising after echinocandin exposure. We report a neutropenic patient who developed a severe sino-orbito-cerebral H. aspergillata infection while receiving empirical caspofungin, successfully controlled by an aggressive strategy associating surgical debridement and combined high-dose regimen of antifungal drugs.
Keywords :
Neutropenia
Young Adult
Acute
Leukemia
Drug Resistance
Male
Fatal Outcome
Fungal
allogeneic haematopoietic stem cell transplantation
Agaricales
Echinocandins
Debridement
Antifungal Agents
Combined Modality Therapy
Brain
Central Nervous System Fungal Infections
basidiomycosis
Molecular Sequence Data
acute myeloid leukaemia
Hormographiella aspergillata
Humans
Myeloid
Cited literature [15 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01405220
Contributor : Floran Bidault <>
Submitted on : Tuesday, November 29, 2016 - 4:14:21 PM
Last modification on : Tuesday, December 1, 2020 - 11:36:08 AM
Long-term archiving on: : Monday, March 27, 2017 - 7:03:31 AM
Contributor : Floran Bidault <>
Submitted on : Tuesday, November 29, 2016 - 4:14:21 PM
Last modification on : Tuesday, December 1, 2020 - 11:36:08 AM
Long-term archiving on: : Monday, March 27, 2017 - 7:03:31 AM
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Heiblig_et_al-2015-Mycoses.pdf
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Distributed under a Creative Commons Attribution 4.0 International License