Aspergillus spp. invasive external otitis: favourable outcome with a medical approach

Abstract : Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was Aspergillus flavus (n = 10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days (158-804 days). None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otological sequelae were reported, including hearing impairment (n = 7) and facial palsy (n = 3).
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Clinical Microbiology and Infection, Wiley, 2016, 22 (5), pp.434--437. 〈10.1016/j.cmi.2015.12.027〉
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Soumis le : mardi 29 novembre 2016 - 16:14:00
Dernière modification le : jeudi 11 janvier 2018 - 06:25:24

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E. Marchionni, P. Parize, A. Lefèvre, P. Vironneau, M. E. Bougnoux, et al.. Aspergillus spp. invasive external otitis: favourable outcome with a medical approach. Clinical Microbiology and Infection, Wiley, 2016, 22 (5), pp.434--437. 〈10.1016/j.cmi.2015.12.027〉. 〈pasteur-01405210〉

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