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Journal Articles Clinical Microbiology and Infection Year : 2016

Aspergillus spp. invasive external otitis: favourable outcome with a medical approach

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Abstract

Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was Aspergillus flavus (n = 10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days (158-804 days). None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otological sequelae were reported, including hearing impairment (n = 7) and facial palsy (n = 3).

Dates and versions

pasteur-01405210 , version 1 (29-11-2016)

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E. Marchionni, P. Parize, A. Lefèvre, P. Vironneau, M. E. Bougnoux, et al.. Aspergillus spp. invasive external otitis: favourable outcome with a medical approach. Clinical Microbiology and Infection, 2016, 22 (5), pp.434--437. ⟨10.1016/j.cmi.2015.12.027⟩. ⟨pasteur-01405210⟩
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