A molecular marker of artemisinin-resistant Plasmodium falciparum malaria, Nature, vol.10, issue.7481, pp.50-55, 2014. ,
DOI : 10.1038/nature12876
URL : https://hal.archives-ouvertes.fr/pasteur-00921203
Malaria, New England Journal of Medicine, vol.371, issue.5, pp.411-434, 2014. ,
DOI : 10.1056/NEJMoa1314981
URL : https://hal.archives-ouvertes.fr/inserm-00854378
Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia, Journal of Infectious Diseases, vol.211, issue.5, pp.670-79, 2015. ,
DOI : 10.1093/infdis/jiu491
Malaria, New England Journal of Medicine, vol.361, issue.5, pp.455-67, 2009. ,
DOI : 10.1056/NEJMoa0808859
URL : https://hal.archives-ouvertes.fr/hal-01199794
Evidence of Artemisinin-Resistant Malaria in Western Cambodia, New England Journal of Medicine, vol.359, issue.24, pp.2619-2639, 2008. ,
DOI : 10.1056/NEJMc0805011
Dihydroartemisinin???piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study, The Lancet Infectious Diseases, vol.16, issue.3, pp.357-65, 2016. ,
DOI : 10.1016/S1473-3099(15)00487-9
Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations, BMC Medicine, vol.47, issue.3, p.305, 2015. ,
DOI : 10.1186/s12916-015-0539-5
Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment, Antimicrobial Agents and Chemotherapy, vol.59, issue.8, pp.4719-4745, 2015. ,
DOI : 10.1128/AAC.00835-15
Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study, The Lancet Infectious Diseases, vol.15, issue.6, pp.683-91, 2015. ,
DOI : 10.1016/S1473-3099(15)70049-6
Efficacy of Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010, Antimicrobial Agents and Chemotherapy, vol.57, issue.2, pp.818-844, 2008. ,
DOI : 10.1128/AAC.00686-12
An alternative to serum for cultivation of Plasmodium falciparum in vitro, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.91, issue.3, pp.363-65, 1997. ,
DOI : 10.1016/S0035-9203(97)90110-3
Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes, Malaria Journal, vol.419, issue.1, p.206, 2016. ,
DOI : 10.1186/s12936-016-1258-x
URL : https://hal.archives-ouvertes.fr/pasteur-01303621
SNPEVG: a graphical tool for GWAS graphing with mouse clicks Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites, BMC Bioinformatics Antimicrob Agents Chemother, vol.13, issue.55, pp.319-3908, 2011. ,
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies, Nature Communications, vol.54, p.11553, 2016. ,
DOI : 10.1038/ncomms11553
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine., Proceedings of the National Academy of Sciences, vol.91, issue.3, pp.1143-1190, 1994. ,
DOI : 10.1073/pnas.91.3.1143
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number, The Lancet, vol.364, issue.9432, pp.438-485, 2004. ,
DOI : 10.1016/S0140-6736(04)16767-6
Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin, The Journal of Infectious Diseases, vol.194, issue.4, pp.528-563, 2006. ,
DOI : 10.1086/507115
Recurrent Gene Amplification and Soft Selective Sweeps during Evolution of Multidrug Resistance in Malaria Parasites, Molecular Biology and Evolution, vol.24, issue.2, pp.562-73, 2007. ,
DOI : 10.1093/molbev/msl185
Susceptibility to Mefloquine, Antimicrobial Agents and Chemotherapy, vol.59, issue.5, pp.2934-2971, 2015. ,
DOI : 10.1128/AAC.05163-14
Eff ects on growth, hemoglobin metabolism and paralogous gene expression resulting from disruption of genes encoding the digestive vacuole plasmepsins of Plasmodium falciparum ,
-infected Red Blood Cells Following Treatment with Antimalarial Drugs, Ultrastructural Pathology, vol.57, issue.5, pp.214-239, 2011. ,
DOI : 10.1016/S0020-7519(02)00194-7
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum, The EMBO Journal, vol.3, issue.13, pp.3000-3011, 2006. ,
DOI : 10.1073/pnas.82.9.2784
Polymorphisms within PfMDR1 alter the substrate specifi city for anti-malarial drugs in Plasmodium falciparum, Mol Microbiol, vol.70, pp.786-98, 2008. ,
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia, Nature Genetics, vol.89, issue.6, pp.648-55, 2013. ,
DOI : 10.1101/gr.094052.109
Arterolane Maleate Plus Piperaquine Phosphate for Treatment of Uncomplicated Plasmodium falciparum Malaria: A Comparative, Multicenter, Randomized Clinical Trial, Clinical Infectious Diseases, vol.55, issue.5, pp.663-71, 2012. ,
DOI : 10.1093/cid/cis475