M. T. Silva, F. Portaels, and J. Pedrosa, Pathogenetic mechanisms of the intracellular parasite Mycobacterium ulcerans leading to Buruli ulcer, The Lancet Infectious Diseases, vol.9, issue.11, pp.699-710, 2009.
DOI : 10.1016/S1473-3099(09)70234-8

T. S. Van-der-werf, T. Stinear, Y. Stienstra, W. T. Van-der-graaf, and P. L. Small, Mycolactones and Mycobacterium ulcerans disease, The Lancet, vol.362, issue.9389, pp.1062-1064, 2003.
DOI : 10.1016/S0140-6736(03)14417-0

M. Wansbrough-jones and R. Phillips, Buruli ulcer: emerging from obscurity, The Lancet, vol.367, issue.9525, pp.1849-1858, 2006.
DOI : 10.1016/S0140-6736(06)68807-7

G. Amofah, Buruli Ulcer in Ghana: Results of a National Case Search, Emerging Infectious Diseases, vol.8, issue.2, pp.167-170, 2002.
DOI : 10.3201/eid0802.010119

S. J. Khan and S. Muneeb, Cutaneous leishmaniasis in Pakistan, Dermatol Online J, vol.11, issue.4, 2005.

B. C. Ross, Detection of Mycobacterium ulcerans in environmental samples during an outbreak of ulcerative disease, Appl Environ Microbiol, vol.63, pp.4135-4138, 1997.

M. Debacker, C. Zinsou, J. Aguiar, W. M. Meyers, and F. Portaels, Disease (Buruli Ulcer) Following a Human Bite, Clinical Infectious Diseases, vol.36, issue.5, pp.67-68, 2003.
DOI : 10.1086/367660

R. W. Merritt, Ecology and Transmission of Buruli Ulcer Disease: A Systematic Review, PLoS Neglected Tropical Diseases, vol.30, issue.1, p.911, 2010.
DOI : 10.1371/journal.pntd.0000911.s001

J. Guarner, Infection, Emerging Infectious Diseases, vol.9, issue.6, pp.651-656, 2003.
DOI : 10.3201/eid0906.020485

J. Hayman, Mycobacterium ulcerans infection, The Lancet, vol.337, issue.8733, 1991.
DOI : 10.1016/0140-6736(91)90791-M

J. Hayman and A. Mcqueen, The pathology of mycobacterium ulcerans infection, Pathology, vol.17, issue.4, pp.594-600, 1985.
DOI : 10.3109/00313028509084759

D. Yeboah-manu, Systemic suppression of interferon-?? responses in Buruli ulcer patients resolves after surgical excision of the lesions caused by the extracellular pathogen Mycobacterium ulcerans, Journal of Leukocyte Biology, vol.79, issue.6, pp.1150-1156, 2006.
DOI : 10.1189/jlb.1005581

R. Phillips, Immunosuppressive Signature of Cutaneous Mycobacterium ulcerans Infection in the Peripheral Blood of Patients with Buruli Ulcer Disease, J Infect Dis, 2009.
URL : https://hal.archives-ouvertes.fr/pasteur-01402286

K. M. George, Mycolactone: A Polyketide Toxin from Mycobacterium ulcerans Required for Virulence, Science, vol.283, issue.5403, pp.854-857, 1999.
DOI : 10.1126/science.283.5403.854

H. Hong, C. Demangel, S. J. Pidot, P. F. Leadlay, and T. Stinear, Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria, Natural Product Reports, vol.45, issue.3, pp.447-454, 2008.
DOI : 10.1039/b803101k

E. Coutanceau, toxin mycolactone, The Journal of Experimental Medicine, vol.22, issue.6, pp.1395-1403, 2007.
DOI : 10.1016/0022-1759(94)90236-4
URL : https://hal.archives-ouvertes.fr/pasteur-01402321

E. Coutanceau, Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin, Cellular Microbiology, vol.34, issue.8, pp.1187-1196, 2005.
DOI : 10.1016/S0140-6736(99)01156-3

C. Demangel, T. P. Stinear, and S. T. Cole, Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans, Nature Reviews Microbiology, vol.4, issue.1, pp.50-60, 2009.
DOI : 10.1093/molbev/msm092

L. Guenin-mace, Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression, Proceedings of the National Academy of Sciences, vol.108, issue.31, pp.12833-12838, 2011.
DOI : 10.1073/pnas.1016496108
URL : https://hal.archives-ouvertes.fr/pasteur-00738806

A. A. Pahlevan, The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-kappa B function, J Immunol, vol.163, pp.3928-3935, 1999.

R. Rohatgi, The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly, Cell, vol.97, issue.2, pp.221-231, 1999.
DOI : 10.1016/S0092-8674(00)80732-1

A. J. Thrasher and S. O. Burns, WASP: a key immunological multitasker, Nature Reviews Immunology, vol.37, issue.3, pp.182-192, 2010.
DOI : 10.1038/nri2724

E. M. Kovacs, N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway, Nature Cell Biology, vol.104, issue.8, pp.934-943, 2011.
DOI : 10.1038/ncb2290

T. Lefever, N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF?? pathways, Journal of Cell Science, vol.123, issue.1, pp.128-140, 2010.
DOI : 10.1242/jcs.053835

A. Lyubimova, Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice, Journal of Clinical Investigation, vol.120, issue.2, pp.446-456, 2010.
DOI : 10.1172/JCI36478DS1

S. Etienne-manneville, Polarity proteins in migration and invasion, Oncogene, vol.27, issue.55, pp.6970-6980, 2008.
DOI : 10.1038/ncb1603

J. R. Peterson, Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation, Nature Structural & Molecular Biology, vol.8, issue.8, pp.747-755, 2004.
DOI : 10.1006/jmbi.1997.1044

D. S. Ridley and M. J. Ridley, The evolution of the lesion in cutaneous leishmaniasis, The Journal of Pathology, vol.73, issue.1, pp.83-96, 1983.
DOI : 10.1002/path.1711410109

S. A. Grevelink, E. A. Lerner, and . Leishmaniasis, Leishmaniasis, Journal of the American Academy of Dermatology, vol.34, issue.2, pp.257-272, 1996.
DOI : 10.1016/S0190-9622(96)80121-6

U. Sharma and S. Singh, Immunobiology of leishmaniasis, Indian J Exp Biol, vol.47, pp.412-423, 2009.

G. Kolde, T. Luger, C. Sorg, and C. Sunderkotter, Successful Treatment of Cutaneous Leishmaniasis Using Systemic Interferon-Gamma, Dermatology, vol.192, issue.1, pp.56-60, 1996.
DOI : 10.1159/000246316

J. Saab, Cutaneous leishmaniasis mimicking inflammatory and neoplastic processes: a clinical, histopathological and molecular study of 57 cases, Journal of Cutaneous Pathology, vol.43, issue.2 Pt 1, pp.251-262, 2012.
DOI : 10.1111/j.1600-0560.2011.01844.x

G. Tasew, Systemic FasL and TRAIL Neutralisation Reduce Leishmaniasis Induced Skin Ulceration, PLoS Neglected Tropical Diseases, vol.106, issue.10, p.844, 2010.
DOI : 10.1371/journal.pntd.0000844.s003
URL : http://doi.org/10.1371/journal.pntd.0000844

B. Rethi and L. Eidsmo, FasL and TRAIL signaling in the skin during cutaneous leishmaniasis - implications for tissue immunopathology and infectious control, Frontiers in Immunology, vol.3, p.163, 2012.
DOI : 10.3389/fimmu.2012.00163

F. Oliveira, Lesion Size Correlates with Leishmania Antigen-Stimulated TNF-Levels in Human Cutaneous Leishmaniasis, American Journal of Tropical Medicine and Hygiene, vol.85, issue.1, pp.70-73, 2011.
DOI : 10.4269/ajtmh.2011.10-0680

D. S. Snyder and P. L. Small, Uptake and cellular actions of mycolactone, a virulence determinant for Mycobacterium ulcerans, Microbial Pathogenesis, vol.34, issue.2, pp.91-101, 2003.
DOI : 10.1016/S0882-4010(02)00210-3

K. M. George, L. Pascopella, D. M. Welty, and P. L. Small, A Mycobacterium ulcerans Toxin, Mycolactone, Causes Apoptosis in Guinea Pig Ulcers and Tissue Culture Cells, Infection and Immunity, vol.68, issue.2, pp.877-883, 2000.
DOI : 10.1128/IAI.68.2.877-883.2000

K. Huygen, Prospects for vaccine development against Buruli disease, Expert Review of Vaccines, vol.2, issue.4, pp.561-569, 2003.
DOI : 10.1586/14760584.2.4.561

B. H. Ji, A. Chauffour, J. Robert, S. Lefrancois, and V. Jarlier, Orally Administered Combined Regimens for Treatment of Mycobacterium ulcerans Infection in Mice, Antimicrobial Agents and Chemotherapy, vol.51, issue.10, pp.3737-3739, 2007.
DOI : 10.1128/AAC.00730-07

C. Rajput, Neural Wiskott-Aldrich Syndrome Protein (N-WASP)-mediated p120-Catenin Interaction with Arp2-Actin Complex Stabilizes Endothelial Adherens Junctions, Journal of Biological Chemistry, vol.288, issue.6
DOI : 10.1074/jbc.M112.440396

W. A. Nienhuis, Paradoxical Responses After Start of Antimicrobial Treatment in Mycobacterium ulcerans Infection, Clinical Infectious Diseases, vol.54, issue.4, pp.519-526, 2012.
DOI : 10.1093/cid/cir856

N. D. Friedman, A. H. Mcdonald, M. E. Robson, and D. P. O-'brien, Corticosteroid Use for Paradoxical Reactions during Antibiotic Treatment for Mycobacterium ulcerans, PLoS Neglected Tropical Diseases, vol.6, issue.9, p.1767, 2012.
DOI : 10.1371/journal.pntd.0001767.t001

J. M. Trevillyan and P. Johnson, Steroids control paradoxical worsening of Mycobacterium ulcerans infection following initiation of antibiotic therapy, The Medical Journal of Australia, vol.198, issue.8, pp.443-444, 2013.
DOI : 10.5694/mja12.11559