Ethanol lock therapy in pediatric hematology and oncology, Pediatric Blood & Cancer, vol.80, issue.1, pp.18-25, 2013. ,
DOI : 10.1002/pbc.24249
Taurolidine and Catheter-related Bloodstream Infection: A Systematic Review of the Literature, Journal of Pediatric Gastroenterology and Nutrition, vol.47, issue.2, pp.179-86, 2008. ,
DOI : 10.1097/MPG.0b013e318162c428
Taurolin for the prevention of parenteral nutrition related infection: antimicrobial activity and long-term use, Clinical Nutrition, vol.12, issue.6, pp.365-373, 1993. ,
DOI : 10.1016/0261-5614(93)90034-2
Observational study of need for 14 thrombolytic therapy and incidence of bacteremia using taurolidine-citrate-heparin, 15 taurolidine-citrate and heparin catheter locks in patients treated with hemodialysis, pp.233-241, 2012. ,
Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution, Nephrology Dialysis Transplantation, vol.19, issue.6, pp.1546-51, 2004. ,
DOI : 10.1093/ndt/gfh014
Mini-review: Antimicrobial central venous catheters ??? recent advances and strategies, Biofouling, vol.47, issue.6, pp.609-629, 2011. ,
DOI : 10.1124/pr.55.1.2
A Comparison of Two Antimicrobial-Impregnated Central Venous Catheters, New England Journal of Medicine, vol.340, issue.1, pp.1-8, 1999. ,
DOI : 10.1056/NEJM199901073400101
Long-term silicone central venous 31 catheters impregnated with minocycline and rifampin decrease rates of catheter-related 32 bloodstream infection in cancer patients: a prospective randomized clinical trial, J Clin Oncol, vol.33, issue.22, pp.3163-71, 2004. ,
Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter???Related Infection: 2009 Update by the Infectious Diseases Society of America, Clinical Infectious Diseases, vol.49, issue.1, pp.1-45, 2009. ,
DOI : 10.1086/599376
Diagnosis of Venous Access Port--Related Infections, Clinical Infectious Diseases, vol.29, issue.5, pp.1197-202, 1999. ,
DOI : 10.1086/313444
Treatment of long-term intravascular catheter-related bacteraemia with antibiotic lock: randomized, placebo-controlled trial, Journal of Antimicrobial Chemotherapy, vol.55, issue.1, pp.90-94, 2005. ,
DOI : 10.1093/jac/dkh488
Comparison of diagnostic specimens and methods to evaluate infected venous access ports, The American Journal of Surgery, vol.170, issue.6, pp.665-674, 1995. ,
DOI : 10.1016/S0002-9610(99)80038-5
Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures, The Lancet, vol.354, issue.9184, pp.1071-1078, 1999. ,
DOI : 10.1016/S0140-6736(98)11134-0
Value of differential quantitative blood cultures in the diagnosis of catheter-related sepsis, European Journal of Clinical Microbiology & Infectious Diseases, vol.312, issue.5, pp.10-403, 1992. ,
DOI : 10.1007/BF01961854
Differential quantitative blood cultures for the diagnosis of catheter-related bloodstream infections associated with short- and long-term catheters: A prospective study, Diagnostic Microbiology and Infectious Disease, vol.50, issue.3, pp.167-72, 2004. ,
DOI : 10.1016/j.diagmicrobio.2004.07.007
Differential 16 time to positivity: a useful method for diagnosing catheter-related bloodstream infections, p.17 ,
Meta-Analysis: Methods for Diagnosing Intravascular Device???Related Bloodstream Infection, Annals of Internal Medicine, vol.142, issue.6, pp.451-66, 2005. ,
DOI : 10.7326/0003-4819-142-6-200503150-00011
Diagnosis of 21 central venous catheter-related sepsis. Critical level of quantitative tip cultures, pp.873-880, 1987. ,
A Semiquantitative Culture Method for Identifying Intravenous-Catheter-Related Infection, New England Journal of Medicine, vol.296, issue.23, pp.1305-1314, 1977. ,
DOI : 10.1056/NEJM197706092962301
Diagnosis 26 of vascular catheter-related bloodstream infection: a meta-analysis, J Clin Microbiol, vol.27, issue.35, pp.928-964, 1997. ,
Improving diagnosis of central venous catheter-related bloodstream infection by using differential time to positivity as a hospital-wide approach at a cancer hospital, Journal of Infection, vol.59, issue.5, pp.317-340, 2009. ,
DOI : 10.1016/j.jinf.2009.09.003
Time to Blood Culture Positivity as a Marker for Catheter-Related Candidemia, Journal of Clinical Microbiology, vol.46, issue.7, pp.2222-2228, 2008. ,
DOI : 10.1128/JCM.00214-08
Review of techniques for diagnosis of catheter-related Candida biofilm infections, Current Fungal Infection Reports, vol.25, issue.Suppl1, pp.237-280, 2008. ,
DOI : 10.1007/s12281-008-0035-x
Use of a simple criteria set for guiding 36 echocardiography in nosocomial Staphylococcus aureus bacteremia, Clin Infect Dis, vol.53, pp.37-38, 2011. ,
Use of Universal 16S rRNA Gene PCR as a Diagnostic Tool for Venous Access Port-Related Bloodstream Infections, Journal of Clinical Microbiology, vol.51, issue.3 ,
DOI : 10.1128/JCM.02414-12
Biofilm monitoring using biofilm specific 4 biomarkers, Biofilms 5 International Conference, pp.10-12, 2012. ,
F media for diagnosis of fungemia by the bactec 9240 system, J Clin, vol.7 ,
Performance of Candida real-time 9 ,
Vascular catheters with a nonleaching poly- 12 sulfobetaine surface modification reduce thrombus formation and microbial attachment. Sci 13, Transl Med, vol.4, pp.153-185, 2012. ,
Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface, Science Translational Medicine, vol.4, issue.153, pp.153-163, 2012. ,
DOI : 10.1126/scitranslmed.3004528
Influence of a calcium-specific chelant 17 on biofilm removal, Appl Environ Microbiol, vol.46, pp.1236-1244, 1983. ,
The role of chelators in preventing biofilm formation and catheter-related bloodstream infections, Current Opinion in Infectious Diseases, vol.21, issue.4, pp.385-92, 2008. ,
DOI : 10.1097/QCO.0b013e32830634d8
Activity of novel 22 antibiotic lock solutions in a model against isolates of catheter-related bloodstream infections, p.23 ,
Chelator-based 25 catheter lock solutions in eradicating organisms in biofilm, Antimicrob Agents Chemother, vol.26, issue.57, pp.586-594, 2013. ,
Full and broad-spectrum in vivo 28 eradication of catheter-associated biofilms using gentamicin-EDTA antibiotic lock therapy, Antimicrob Agents Chemother, p.29, 2012. ,
Metabolite-enabled eradication of bacterial persisters by aminoglycosides, Nature, vol.31, issue.7346, pp.216-236, 2011. ,
DOI : 10.1038/nature10069
Infections, The Journal of Infectious Diseases, vol.193, issue.2, pp.180-186, 2006. ,
DOI : 10.1086/498914
Microbiology: Jekyll or hide?, Nature, vol.51, issue.7018, pp.680-681, 2004. ,
DOI : 10.1128/JB.186.17.5692-5698.2004
agr-Mediated Dispersal of Staphylococcus aureus Biofilms, PLoS Pathogens, vol.70, issue.10, p.37 ,
DOI : 10.1371/journal.ppat.1000052.s001
Modality of bacterial growth presents unique targets: how do we treat biofilm-mediated infections?, Current Opinion in Microbiology, vol.13, issue.5, pp.610-615, 2010. ,
DOI : 10.1016/j.mib.2010.09.007
In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections, Journal of Antimicrobial Chemotherapy, vol.68, issue.1, pp.126-156, 2012. ,
DOI : 10.1093/jac/dks376
early biofilms, Human Vaccines, vol.7, issue.6, pp.630-638, 2011. ,
DOI : 10.4161/hv.7.6.15407
In Vitro Activity and Durability of a Combination of an Antibiofilm and an Antibiotic against Vascular Catheter Colonization, Antimicrobial Agents and Chemotherapy, vol.57, issue.1, pp.621-626, 2013. ,
DOI : 10.1128/AAC.01646-12
Rescue therapy of difficult-to-treat indwelling central venous catheter-related bacteremias in cancer patients: a review for practical purposes, Expert Review of Anti-infective Therapy, vol.11, issue.2, pp.179-86, 2013. ,
DOI : 10.1586/eri.12.160
Risk factors for early catheter-related infections in cancer patients, Cancer, vol.28, issue.7, pp.1586-92, 2007. ,
DOI : 10.1002/cncr.22942
Infectious port complications are more frequent in 17 younger patients with hematologic malignancies than in solid tumor patients, Oncology, vol.18, issue.74, pp.237-281, 2008. ,
Catheter tip position as a risk factor for 20 thrombosis associated with the use of subcutaneous infusion ports, Support Care Cancer, vol.21, issue.13, pp.325-356, 2005. ,
Clinical practice guidelines for the 23 management of candidiasis: 2009 update by the Infectious Diseases Society of America, Clin Infect Dis, vol.24, issue.48, pp.503-538, 2009. ,
Early removal of central venous catheter in 26 patients with candidemia does not improve outcome: analysis of 842 patients from 2 ,
Management of Central Venous Catheters in Patients with Cancer and Candidemia, Clinical Infectious Diseases, vol.38, issue.8, pp.1119-1146, 2004. ,
DOI : 10.1086/382874
Optimal antimicrobial catheter 31 lock solution, using different combinations of minocycline, EDTA, and 25-percent ethanol, 32 rapidly eradicates organisms embedded in biofilm, Antimicrob Agents Chemother, vol.51, pp.33-78, 2007. ,
In Vitro Analyses of Ethanol Activity against Candida albicans Biofilms, Antimicrobial Agents and Chemotherapy, vol.56, issue.8, pp.4487-4496, 2012. ,
DOI : 10.1128/AAC.00263-12
Ethanol Locks Therapy for Resolution of Fungal Catheter Infections, The Pediatric Infectious Disease Journal, vol.30, issue.12, pp.1105-1112, 2011. ,
DOI : 10.1097/INF.0b013e31822c84a4
Venous Access Port???Related Bacteremia in Patients with Acquired Immunodeficiency Syndrome or Cancer: The Reservoir as a Diagnostic and Therapeutic Tool, Clinical Infectious Diseases, vol.32, issue.12, pp.1776-83, 2001. ,
DOI : 10.1086/320746
Bloodstream Infections in Outpatient Oncology Office, Emerging Infectious Diseases, vol.14, issue.7, pp.1046-52, 2008. ,
DOI : 10.3201/eid1407.070894
Incubation Alone Is Adequate as a Culturing Technique for Cardiac Rhythm Management Devices, Journal of Clinical Microbiology, vol.47, issue.12, pp.9-4168, 2009. ,
DOI : 10.1128/JCM.01354-09
Morbidity associated with 11 long-term use of totally implantable ports in patients with AIDS, Clin Infect Dis, vol.29, pp.12-346, 1999. ,
Failure of antibiotic therapy in Staphylococcus epidermidis infection of implantable venous access devices in patients with AIDS, as documented by molecular typing, Clinical Microbiology and Infection, vol.5, issue.4, pp.190-194, 1999. ,
DOI : 10.1111/j.1469-0691.1999.tb00122.x
Catheter- 17 related infection in patients on home parenteral nutrition: results of a prospective survey, Nutr, vol.21, pp.33-41, 2002. ,
Antibiotic Lock-Technique for the Treatment of Catheter-Related Bloodstream Infections, Journal of Chemotherapy, vol.18, issue.2, pp.152-158, 2003. ,
DOI : 10.1097/00003246-200104001-00011
Taurolidine is effective in the treatment of central 22 venous catheter-related bloodstream infections in cancer patients, Int J Antimicrob Agents, vol.23, issue.24, pp.491-496, 2004. ,
Treatment of long-term intravascular catheter-related bacteraemia with antibiotic-lock therapy, Journal of Antimicrobial Chemotherapy, vol.58, issue.4, pp.816-837, 2006. ,
DOI : 10.1093/jac/dkl318
Conclusions., Infection Control & Hospital Epidemiology, vol.44, issue.02, pp.125-155, 2008. ,
DOI : 10.1086/313591
Effectiveness of 31 the antibiotic lock therapy for the treatment of port-related enterococci, Gram-negative, p.32 ,
Ethanol lock therapy for the treatment of catheter-related infections in haemophilia patients, Haemophilia, vol.19, issue.Suppl 2, pp.1267-1302, 2009. ,
DOI : 10.1111/j.1365-2516.2009.02075.x
Ethanol lock therapy for catheter-associated blood stream infections in a pediatric intensive care unit, Pediatric Critical Care Medicine, vol.12, issue.6, pp.292-298, 2011. ,
DOI : 10.1097/PCC.0b013e318219267c