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Journal articles
Selective propensity of bovine jugular vein material to bacterial adhesions: An in-vitro study
Abstract : BACKGROUND: Percutaneous pulmonary valve implantation (PPVI) using Melody valve made of bovine jugular vein is safe and effective. However, infective endocarditis has been reported for unclear reasons. We sought to assess the impact of valvular substrates on selective bacterial adhesion. METHODS: Three valved stents (Melody valve, homemade stents with bovine and porcine pericardium) were tested in-vitro for bacterial adhesion using Staphylococcus aureus and Streptococcus sanguinis strains. RESULTS: Bacterial adhesion was higher on bovine jugular venous wall for S. aureus and on Melody valvular leaflets for S. sanguinis in control groups and significantly increased in traumatized Melody valvular leaflets with both bacteria (traumatized vs non traumatized: p=0.05). Bacterial adhesion was lower on bovine pericardial leaflets. CONCLUSION: Selective adhesion of S. aureus and S. sanguinis pathogenic strains to Melody valve tissue was noted on healthy tissue and increased after implantation procedural steps.
Keywords :
Staphylococcus aureus/isolation & purification
Melody valve
Animals
Bacterial Adhesion/*physiology
Bioprosthesis/*microbiology
Cattle
Endocarditis
Fallot
Heart Valve Prosthesis Implantation/*adverse effects
Heart Valve Prosthesis/*microbiology
Humans
Jugular Veins/*microbiology/transplantation
Streptococcus sanguis/isolation & purification
Swine
Transcatheter pulmonary valve
https://hal-pasteur.archives-ouvertes.fr/pasteur-01378736
Contributor : Anne Lassailly-Bondaz Connect in order to contact the contributor
Submitted on : Monday, October 10, 2016 - 4:47:23 PM
Last modification on : Tuesday, October 19, 2021 - 10:27:43 PM
Contributor : Anne Lassailly-Bondaz Connect in order to contact the contributor
Submitted on : Monday, October 10, 2016 - 4:47:23 PM
Last modification on : Tuesday, October 19, 2021 - 10:27:43 PM