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Journal articles
Microtubule dynamics and signal transduction at the immunological synapse: new partners and new connections.
Abstract : Antigen recognition induces T cells to polarize towards antigen presenting cells (APC) generating an organized cell interface named the immunological synapse. T-cell microtubules (MTs) reorient the MT-organizing centre (MTOC) to the immunological synapse central region, while MT irradiate towards the synapse periphery. Martín-Cófreces et al (2012) describe in this issue that the MT plus-end-binding protein 1 (EB1) interacts with TCR cytosolic regions and mediate the organization of an immunological synapse fully functional to transduce activation signals.
Cited literature [11 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01371060
Contributor : Vincenzo Di Bartolo <>
Submitted on : Friday, September 23, 2016 - 6:16:30 PM
Last modification on : Monday, January 13, 2020 - 5:08:07 PM
Contributor : Vincenzo Di Bartolo <>
Submitted on : Friday, September 23, 2016 - 6:16:30 PM
Last modification on : Monday, January 13, 2020 - 5:08:07 PM
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emboj2012276a.pdf
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