 |
Journal articles
Multicentric Castleman Disease in an HHV8-Infected Child Born to Consanguineous Parents With Systematic Review
S. Leroy
1, 2
D. Moshous
3
O. Cassar
4
Y. Reguerre
5
M. Byun
6
V. Pedergnana
7
D. Canioni
8, 5
A. Gessain
4
E. Oksenhendler
9
C. Fieschi
9
N. Mahlaoui
1
J.-P. Riviere
5
M. Herbigneaux
5
M. Muszlak
10
J.-P. Arnaud
10
A. Fischer
11
C. Picard
11, 1
S. Blanche
S. Plancoulaine
7
J.-L. Casanova
1, 6, 7
C. Picard 11, 1
Author
S. Blanche
Author
S. Plancoulaine 7
Author IdHAL : sabine-plancoulaine ResearcherId : http://www.researcherid.com/rid/E-2824-2017 ORCID : https://orcid.org/0000-0003-0725-8306
J.-L. Casanova 1, 6, 7
Author
1
Assistance Publique-Hôpitaux de Paris, Service d'Immunologie et d'Hématologie Pédiatrique (Hôpital Necker Enfants Malades, 75015 Paris - France)
2
Centre for Statistics in Medicine (United Kingdom)
- University of Oxford [Oxford] (Wellington Square, Oxford OX1 2JD - United Kingdom)
3
Service d'immuno-hématologie pédiatrique [CHU Necker] (149 Rue de Sèvres, 75015 Paris - France)
- AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) (France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
4
EPVO (UMR_3569 / U-Pasteur_3) - Epidémiologie et Physiopathologie des Virus Oncogènes (Département de Virologie, 25-28 rue du Docteur Roux F-75724 Paris Cedex 15 - France)
- CNRS - Centre National de la Recherche Scientifique : UMR_3569 (France)
- UPD7 - Université Paris Diderot - Paris 7 : UMR_3569 (5 rue Thomas-Mann - 75205 Paris cedex 13 - France)
- Institut Pasteur [Paris] : U-Pasteur_3 (25-28, rue du docteur Roux, 75724 Paris cedex 15 - France)
5
Centre hospitalier Félix-Guyon [Saint-Denis, La Réunion] (Site Félix Guyon, Allée des Topazes, 97400, La Réunion - Réunion)
6
St. Giles Laboratory of Human Genetics of Infectious Diseases (1230 York Ave, New York, NY 10065 - United States)
- Rockefeller University [New York] (1230 York Ave, New York, NY 10065, États-Unis - United States)
7
Laboratory of Human Genetics of Infectious Diseases (Institut National de la Santé et de la Recherche Médicale, U550, Paris - France)
- UPD5 - Université Paris Descartes - Paris 5 (12, rue de l'École de Médecine - 75270 Paris cedex 06 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale (101, rue de Tolbiac, 75013 Paris - France)
8
CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
9
Service d'Immunopathologie [Hôpital Saint-Louis, Paris] (France)
- AP-HP - Hopital Saint-Louis [AP-HP] (1 Avenue Claude Vellefaux, 75010 Paris - France)
- UPD7 - Université Paris Diderot - Paris 7 (5 rue Thomas-Mann - 75205 Paris cedex 13 - France)
10
Centre Hospitalier de Mayotte (Mamoudzou, Mayotte - France)
11
Developpement Normal et Pathologique du Système Immunitaire (Gh Necker - Enfants Malades PARIS V
149, Rue de Sèvres
75015 PARIS - France)
- UPD5 - Université Paris Descartes - Paris 5 : UMR-S 768 (12, rue de l'École de Médecine - 75270 Paris cedex 06 - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : UMR-S 768 (101, rue de Tolbiac, 75013 Paris - France)
- CNRS - Centre National de la Recherche Scientifique : UMR-S 768 (France)
Abstract : Childhood multicentric Castleman disease (MCD) is a rare and unexplained lymphoproliferative disorder. We report a human herpesvirus-8 (HHV-8)-infected child, born to consanguineous Comorian parents, who displayed isolated MCD in the absence of any known immunodeficiency. We also systematically review the clinical features of the 32 children previously reported with isolated and unexplained MCD. The characteristics of this patient and the geographic areas of origin of most previous cases suggest that pediatric MCD is associated with HHV-8 infection. Moreover, as previously suggested for Kaposi sarcoma, MCD in childhood may result from inborn errors of immunity to HHV-8 infection.
Document type :
Journal articles
Complete list of metadata
https://hal-pasteur.archives-ouvertes.fr/pasteur-01370956
Contributor : Isma Ziani Connect in order to contact the contributor
Submitted on : Friday, September 23, 2016 - 3:17:58 PM
Last modification on : Wednesday, October 27, 2021 - 3:01:55 PM
Contributor : Isma Ziani Connect in order to contact the contributor
Submitted on : Friday, September 23, 2016 - 3:17:58 PM
Last modification on : Wednesday, October 27, 2021 - 3:01:55 PM
Links full text
Identifiers
- HAL Id : pasteur-01370956, version 1
- DOI : 10.1542/peds.2010-2739
- PUBMED : 22157133
- PUBMEDCENTRAL : PMC3273364
Collections
PASTEUR | CNRS | UNIV-PARIS7 | UNIV-PARIS5 | UNIV-PARIS | UP-SCIENCES
Citation
S. Leroy, D. Moshous, O. Cassar, Y. Reguerre, M. Byun, et al.. Multicentric Castleman Disease in an HHV8-Infected Child Born to Consanguineous Parents With Systematic Review. Pediatrics, American Academy of Pediatrics, 2012, 129 (1), pp.e199 - e203. ⟨10.1542/peds.2010-2739⟩. ⟨pasteur-01370956⟩
Metrics
Les métriques sont temporairement indisponibles